High-Resolution Ex Vivo Tissue Clearing, Lightsheet Imaging, and Data Analysis to Support Macromolecular Drug and Biomarker Distribution in Whole Organs and Tumors
Kumar, Niyanta, Hrobař, Petr, Vagenknecht, Martin, Soukup, Jindrich, Bloomingdale, Peter, Freshwater, Tomoko, Bardehle, Sophia, Peter, Roman, Patterson, Nadia, Mangadu, Ruban, Pastuskovas, Cinthia, Cancilla, Mark
Published in Microscopy and microanalysis (01.08.2022)
Published in Microscopy and microanalysis (01.08.2022)
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Journal Article
Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells
Sukumar, Selvakumar, Wilson, Douglas C, Yu, Ying, Wong, Jerelyn, Naravula, Saraswathi, Ermakov, Grigori, Riener, Romina, Bhagwat, Bhagyashree, Necheva, Antoaneta S, Grein, Jeff, Churakova, Tatyana, Mangadu, Ruban, Georgiev, Peter, Manfra, Denise, Pinheiro, Elaine M, Sriram, Venkataraman, Bailey, Wendy J, Herzyk, Danuta, McClanahan, Terrill K, Willingham, Aarron, Beebe, Amy M, Sadekova, Svetlana
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Published in Cancer research (Chicago, Ill.) (15.08.2017)
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Journal Article
STUB1 is an intracellular checkpoint for interferon gamma sensing
Ng, Simon, Lim, Shuhui, Sim, Adrian Chong Nyi, Mangadu, Ruban, Lau, Ally, Zhang, Chunsheng, Martinez, Sarah Bollinger, Chandramohan, Arun, Lim, U-Ming, Ho, Samantha Shu Wen, Chang, Shih Chieh, Gopal, Pooja, Hong, Lewis Z., Schwaid, Adam, Fernandis, Aaron Zefrin, Loboda, Andrey, Li, Cai, Phan, Uyen, Henry, Brian, Partridge, Anthony W.
Published in Scientific reports (18.08.2022)
Published in Scientific reports (18.08.2022)
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A T-cell-dependent antibody response study using a murine surrogate anti-PD-1 monoclonal antibody as an alternative to a non-human primate model
Plitnick, Lisa M., Hutchins, Beth, Dubey, Sheri, Li, Nianyu, Amin, Rupesh P., Born, Stephanie, Mangadu, Ruban, Phillips, Joseph H., Sriram, Venkataraman, Herzyk, Danuta J.
Published in Journal of immunotoxicology (01.01.2020)
Published in Journal of immunotoxicology (01.01.2020)
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Journal Article
p38 MAPK inhibition reduces diabetes-induced impairment of wound healing
Medicherla, Satyanarayana, Wadsworth, Scott, Cullen, Breda, Silcock, Derek, Ma, Jing Y, Mangadu, Ruban, Kerr, Irene, Chakravarty, Sarvajit, Luedtke, Gregory L, Dugar, Sundeep, Protter, Andrew A, Higgins, Linda S
Published in Diabetes, metabolic syndrome and obesity (23.06.2009)
Published in Diabetes, metabolic syndrome and obesity (23.06.2009)
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Journal Article
Selective p38α mitogen-activated protein kinase inhibitor attenuates lung inflammation and fibrosis in IL-13 transgenic mouse model of asthma
Ma, Jing Ying, Medicherla, Satyanarayana, Kerr, Irene, Mangadu, Ruban, Protter, Andrew A, Higgins, Linda S
Published in Journal of asthma and allergy (16.11.2008)
Published in Journal of asthma and allergy (16.11.2008)
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Journal Article
Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
Chang, Shih Chieh, Gopal, Pooja, Lim, Shuhui, Wei, Xiaona, Chandramohan, Arun, Mangadu, Ruban, Smith, Jeffrey, Ng, Simon, Gindy, Marian, Phan, Uyen, Henry, Brian, Partridge, Anthony William
Published in Cell chemical biology (17.11.2022)
Published in Cell chemical biology (17.11.2022)
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Journal Article
SD-208, a novel transforming growth factor β receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo
UHL, Martin, AULWURM, Steffen, MURPHY, Alison, WONG, Darren H, WICK, Wolfgang, HIGGINS, Linda S, WELLER, Michael, WISCHHUSEN, Jörg, WEILER, Markus, JING YING MA, ALMIREZ, Ramona, MANGADU, Ruban, LIU, Yu-Wang, PLATTEN, Michael, HERRLINGER, Ulrich
Published in Cancer research (Chicago, Ill.) (01.11.2004)
Published in Cancer research (Chicago, Ill.) (01.11.2004)
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Journal Article
In vivo anti-tumor efficacy of afucosylated anti-CS1 monoclonal antibody produced in glycoengineered Pichia pastoris
Gomathinayagam, Sujatha, Laface, Drake, Houston-Cummings, Nga Rewa, Mangadu, Ruban, Moore, Renee, Shandil, Ishaan, Sharkey, Nathan, Li, Huijuan, Stadheim, Terrance A., Zha, Dongxing
Published in Journal of biotechnology (20.08.2015)
Published in Journal of biotechnology (20.08.2015)
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Abstract 543: Preclinical combination strategies to enhance the efficacy of the anti-PD-1 antibody pembrolizumab
Pinheiro, Elaine M., Hinton, Marlene, Mangadu, Ruban, Cai, Mingmei, Phan, Uyen, Nebozhyn, Michael, Hirsch, Heather, Loboda, Andrey, Javaid, Sarah, Wang, Yaolin, Sriram, Venkataraman, Phillips, Joseph H., McClanahan, Terri, Long, Brian
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 269: Evaluation of the antitumor activity of anti-PD-1 immunotherapy as a single agent and in combination with approved agents in preclinical tumor models
Pinheiro, Elaine M., Mangadu, Ruban, Phan, Uyen T., Cai, Mingmei, Ma, Yanhong, Hirsch, Heather A., McClanahan, Terrill K., Moniz, Raymond J., Al-Assaad, Ali-Samer, Basu, Samik, Wang, Yaolin, Sriram, Venkataraman, Phillips, Joseph H., Long, Brian J.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis
Medicherla, Satyanarayana, Ma, Jing Ying, Mangadu, Ruban, Jiang, Yebin, Zhao, Jenny J, Almirez, Ramona, Kerr, Irene, Stebbins, Elizabeth G, O'Young, Gilbert, Kapoun, Ann M, Luedtke, Gregory, Chakravarty, Sarvajit, Dugar, Sundeep, Genant, Harry K, Protter, Andrew A
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Journal Article
Antitumor Activity of TGF-β Inhibitor is Dependent on the Microenvironment
MEDICHERLA, Satyanarayana, LINGYUN LI, WONG, Darren H, HIGGINS, Linda S, JING YING MA, KAPOUN, Ann M, GASPAR, Nicholas J, LIU, Yu-Wang, MANGADU, Ruban, O'YOUNG, Gilbert, PROTTER, Andrew A, SCHREINER, George F
Published in Anticancer research (01.11.2007)
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Published in Anticancer research (01.11.2007)
Journal Article
Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes
Medicherla, Satyanarayana, Protter, Andrew A, Ma, Jing Ying, Mangadu, Ruban, Almirez, Ramona, Koppelman, Bruce, Kerr, Irene, Navas, Tony A, Movius, Fabiola, Reddy, Mamatha, Liu, Yu-Wang, Luedtke, Gregory, Perumattam, John, Mavunkel, Babu, Dugar, Sundeep, Schreiner, George F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Journal Article
Antitumor Activity of TGF-β, Inhibitor is Dependent on the Microenvironment
SATYANARAYANA MEDICHERLA, LINGYUN LI, JING YING MA, ANN M. KAPOUN, NICHOLAS J. GASPAR, YU-WANG LIU, RUBAN MANGADU, GILBERT O'YOUNG, ANDREW A. PROTTER, GEORGE F. SCHREINER, DARREN H. WONG, LINDA S. HIGGINS
Published in Anticancer research (01.11.2007)
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Published in Anticancer research (01.11.2007)
Journal Article
A Selective p38α Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis
Satyanarayana Medicherla, Jing Ying Ma, Ruban Mangadu, Yebin Jiang, Jenny J. Zhao, Ramona Almirez, Irene Kerr, Elizabeth G. Stebbins, Gilbert O'Young, Ann M. Kapoun, Gregory Luedtke, Sarvajit Chakravarty, Sundeep Dugar, Harry K. Genant, Andrew A. Protter
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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Journal Article
Preventive and Therapeutic Potential of p38α-Selective Mitogen-Activated Protein Kinase Inhibitor in Nonobese Diabetic Mice with Type 1 Diabetes
Satyanarayana Medicherla, Andrew A. Protter, Jing Ying Ma, Ruban Mangadu, Ramona Almirez, Bruce Koppelman, Irene Kerr, Tony A. Navas, Fabiola Movius, Mamatha Reddy, Yu-Wang Liu, Gregory Luedtke, John Perumattam, Babu Mavunkel, Sundeep Dugar, George F. Schreiner
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2006)
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