A phase II study of the efficacy and safety of the MET inhibitor capmatinib (INC280) in patients with advanced hepatocellular carcinoma
Qin, Shukui, Chan, Stephen Lam, Sukeepaisarnjaroen, Wattana, Han, Guohong, Choo, Su Pin, Sriuranpong, Virote, Pan, Hongming, Yau, Thomas, Guo, Yabing, Chen, Minshan, Ren, Zhenggang, Xu, Jianming, Yen, Chia-Jui, Lin, Zhong-Zhe, Manenti, Luigi, Gu, Yi, Sun, Yongjian, Tiedt, Ralph, Hao, Lu, Song, Wenjie, Tanwandee, Tawesak
Published in Therapeutic advances in medical oncology (2019)
Published in Therapeutic advances in medical oncology (2019)
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Journal Article
Phase I Pharmacokinetic and Pharmacodynamic Dose-Escalation Study of RG7160 (GA201), the First Glycoengineered Monoclonal Antibody Against the Epidermal Growth Factor Receptor, in Patients With Advanced Solid Tumors
PAZ-ARES, Luis G, GOMEZ-ROCA, Carlos, HOLLINGSWORTH, Simon, BASELGA, José, UMANA, Pablo, MANENTI, Luigi, TABERNERO, Josep, DELORD, Jean-Pierre, CERVANTES, Andres, MARKMAN, Ben, CORRAL, Jesus, SORIA, Jean-Charles, BERGE, Yann, RODA, Desamparados, RUSSELL-YARDE, Fiona
Published in Journal of clinical oncology (01.10.2011)
Published in Journal of clinical oncology (01.10.2011)
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Journal Article
Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation
Schadt, Heiko S, Wolf, Armin, Mahl, Joerg Andreas, Wuersch, Kuno, Couttet, Philippe, Schwald, Marianne, Fischer, Audrey, Lienard, Mathilde, Emotte, Corinne, Teng, Chi-Hse, Skuba, Elizabeth, Richardson, Terrilyn A, Manenti, Luigi, Weiss, Andreas, Graus Porta, Diana, Fairhurst, Robin A, Kullak-Ublick, Gerd A, Chibout, Salah-Dine, Pognan, Francois, Kluwe, William, Kinyamu-Akunda, Jacqueline
Published in Toxicological sciences (01.05.2018)
Published in Toxicological sciences (01.05.2018)
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Journal Article
An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients
VIDAL, Claudia I, MINTZ, Paul J, PASQUALINI, Renata, LU, Karen, ELLIS, Lee M, MANENTI, Luigi, GIAVAZZI, Raffaella, GERSHENSON, David M, BROADDUS, Russell, JINSONG LIU, ARAP, Wadih
Published in Oncogene (25.11.2004)
Published in Oncogene (25.11.2004)
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Journal Article
The Combination of the Tyrosine Kinase Receptor Inhibitor SU6668 with Paclitaxel Affects Ascites Formation and Tumor Spread in Ovarian Carcinoma Xenografts Growing Orthotopically
GAROFALO, Angela, NAUMOVA, Elitza, GIAVAZZI, Raffaella, MANENTI, Luigi, GHILARDI, Carmen, GHISLENI, Gabriele, CANIATTI, Mario, COLOMBO, Tina, CHERRINGTON, Julie M, SCANZIANI, Eugenio, NICOLETTI, Maria Ines
Published in Clinical cancer research (15.08.2003)
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Published in Clinical cancer research (15.08.2003)
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Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy
Manenti, Luigi, Riccardi, Elena, Marchini, Sergio, Naumova, Elitza, Floriani, Irene, Garofalo, Angela, Dossi, Romina, Marrazzo, Eleonora, Ribatti, Domenico, Scanziani, Eugenio, Bani, Mariarosa, Belotti, Dorina, Broggini, Massimo, Giavazzi, Raffaella
Published in Molecular cancer therapeutics (01.05.2005)
Published in Molecular cancer therapeutics (01.05.2005)
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Journal Article
Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors
Curigliano, Giuseppe, Gelderblom, Hans, Mach, Nicolas, Doi, Toshihiko, Tai, David, Forde, Patrick M, Sarantopoulos, John, Bedard, Philippe L, Lin, Chia-Chi, Hodi, F Stephen, Wilgenhof, Sofie, Santoro, Armando, Sabatos-Peyton, Catherine A, Longmire, Tyler A, Xyrafas, Alexandros, Sun, Haiying, Gutzwiller, Sabine, Manenti, Luigi, Naing, Aung
Published in Clinical cancer research (01.07.2021)
Published in Clinical cancer research (01.07.2021)
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Journal Article
2837 Novel therapeutic for crescentic glomerulonephritis through targeting CLDN1 in parietal epithelial cells
Delbet, Jean-Daniel, Anquetil, Vincent, Saitoski, Kevin, Toso, Alberto, Baumert, Thomas, Toovey, Stephen, Manenti, Luigi, Iacone, Roberto, Ulinski, Tim, Lenoir, Olivia, Teixeira, Geoffrey, Tharaux, Pierre-Louis
Published in Nephrology, dialysis, transplantation (23.05.2024)
Published in Nephrology, dialysis, transplantation (23.05.2024)
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Journal Article
Phase I Study of Taminadenant (PBF509/NIR178), an Adenosine 2A Receptor Antagonist, with or without Spartalizumab (PDR001), in Patients with Advanced Non-Small Cell Lung Cancer
Chiappori, Alberto A, Creelan, Ben, Tanvetyanon, Tawee, Gray, Jhanelle E, Haura, Eric B, Thapa, Ram, Barlow, Margaret L, Chen, Zhihua, Chen, Dung Tsa, Beg, Amer A, Boyle, Theresa A, Castro, Julio, Morgan, Liza, Morris, Erick, Aregay, Mehreteab, Hurtado, Felipe K, Manenti, Luigi, Antonia, Scott
Published in Clinical cancer research (01.06.2022)
Published in Clinical cancer research (01.06.2022)
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Journal Article
Claudin-1 Is a Therapeutic Target for Crescentic Glomerulonephritis: TH-PO531
Teixeira, Geoffrey, Delbet, Jean-Daniel, Anquetil, Vincent, Toso, Alberto, Toovey, Stephen, Manenti, Luigi, Iacone, Roberto, Kers, Jesper, Rabelink, Ton J., Saitoski, Kevin, Baumert, Thomas F., Benigni, Ariela, Tomasoni, Susanna, Remuzzi, Giuseppe, Cagarelli, Thomas, Prunotto, Marco, Moll, Solange, Tharaux, Pierre-Louis
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Phase II, Randomized Study of Spartalizumab (PDR001), an Anti-PD-1 Antibody, versus Chemotherapy in Patients with Recurrent/Metastatic Nasopharyngeal Cancer
Even, Caroline, Wang, Hung-Ming, Li, Shau-Hsuan, Ngan, Roger K-C, Dechaphunkul, Arunee, Zhang, Li, Yen, Chia-Jui, Chan, Po Chung, Chakrabandhu, Somvilai, Ma, Brigette B Y, Tanasanvimon, Suebpong, Lee, Victor H F, Lou, Pei-Jen, Li, Zujun, Spira, Alexander I, Sukari, Ammar, Guigay, Joël, McCune, Steven, Gonzalez-Maffe, Juan, Szpakowski, Sebastian, Yao, Yao, Liang, Hongzi, Mataraza, Jennifer, Séchaud, Romain, Manenti, Luigi, Lim, Darren W-T
Published in Clinical cancer research (01.12.2021)
Published in Clinical cancer research (01.12.2021)
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Journal Article
Correction: Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors
Curigliano, Giuseppe, Curigliano, Hans, Mach, Nicolas, Doi, Toshihiko, Tai, David, Forde, Patrick M, Sarantopoulos, John, Bedard, Philippe L, Lin, Chia-Chi, Hodi, F Stephen, Wilgenhof, Sofie, Santoro, Armando, Sabatos-Peyton, Catherine A, Longmire, Tyler A, Xyrafas, Alexandros, Sun, Haiying, Gutzwiller, Sabine, Manenti, Luigi, Naing, Aung
Published in Clinical cancer research (03.09.2024)
Published in Clinical cancer research (03.09.2024)
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Journal Article
Phase I study of HFB200301, a first-in-class TNFR2 agonist monoclonal antibody in patients with solid tumors selected via Drug Intelligent Science (DIS)
Spira, Alexander I., Naing, Aung, Babiker, Hani M., Borad, Mitesh J., Garralda, Elena, Leventakos, Konstantinos, Oppelt, Peter John, Roda, Desamparados, Zugazagoitia, Jon, Hatzis, Christos, Chen, Margaret, Gan, Jinping, Raue, Andreas, Adrian, Francisco, Manenti, Luigi, El-Khoueiry, Anthony B.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: Implications for ascites formation
BELOTTI, Dorina, PAGANONI, Paola, MANENTI, Luigi, GAROFALO, Angela, MARCHINI, Sergio, TARABOLETTI, Giulia, GIAVAZZI, Raffaella
Published in Cancer research (Chicago, Ill.) (01.09.2003)
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Published in Cancer research (Chicago, Ill.) (01.09.2003)
Journal Article
Abstract CT183: Phase (Ph) I/II study of MBG453± spartalizumab (PDR001) in patients (pts) with advanced malignancies
Curigliano, Giuseppe, Gelderblom, Hans, Mach, Nicolas, Doi, Toshihiko, Tai, Wai Meng David, Forde, Patrick, Sarantopoulos, John, Bedard, Philippe L., Lin, Chia-Chi, Hodi, Stephen, Wilgenhof, Sofie, Santoro, Armando, Sabatos-Peyton, Catherine, Longmire, Tyler, Wan, Kitty, Nikolopoulos, Panagiotis, Manenti, Luigi, Naing, Aung
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation
Schadt, Heiko S, Wolf, Armin, Mahl, Joerg Andreas, Wuersch, Kuno, Couttet, Philippe, Schwald, Marianne, Fischer, Audrey, Lienard, Mathilde, Emotte, Corinne, Teng, Chi-Hse, Skuba, Elizabeth, Richardson, Terrilyn A, Manenti, Luigi, Weiss, Andreas, Graus Porta, Diana, Fairhurst, Robin A, Kullak-Ublick, Gerd A, Chibout, Salah-Dine, Pognan, Francois, Kluwe, William, Kinyamu-Akunda, Jacqueline
Published in Toxicological sciences (01.05.2018)
Published in Toxicological sciences (01.05.2018)
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Journal Article
Abstract LB284: CLAUDIN-1 targeting antibody ALE.C04 drives single activity and restores anti-PD1 efficacy in solid tumors
Toso, Alberto, Teixeira, Geoffrey, Zimmermann, Tina, Gill, Stefanie Gill, Schmitter, Daniela, Meyer, Markus, Muller, Marion, Mailly, Laurent, Baumert, Thomas, Manenti, Luigi, Iacone, Roberto
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
Abstract CT150: Phase II study of spartalizumab (PDR001) vs chemotherapy (CT) in patients with recurrent/metastatic nasopharyngeal cancer (NPC)
Lim, Darren Wan-Teck, Wang, Hung-Ming, Li, Shau-Hsuan, Ngan, Roger, Dechaphunkul, Arunee, Zhang, Li, Yen, Chia Jui, Chan, Po Chung, Chakrabandhu, Somvilai, Ma, Brigette, Tanasanvimon, Suebpong, Lee, Victor, Lou, Pei-Jen, Li, Zujun, Spira, Alexander, Sukari, Ammar, Guigay, Joël, McCune, Steven, Sun, Yongjian, Szpakowski, Sebastian, Yao, Yao, Fan, Xueqiang, Manenti, Luigi, Even, Caroline
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract LB012: Claudin-1 is a driver and therapeutic target for cholangiocarcinoma
Muller, Marion, Nehme, Zeina, Crouchet, Emilie, Jühling, Frank, Röhlen, Natascha, Pessaux, Patrick, Felli, Emanuele, Goyal, Lipika, Meyer, Markus, Iacone, Roberto, Toso, Alberto, Manenti, Luigi, Laquerriere, Patrice, Venkatasamy, Aïna, Bardeesy, Nabeel, Schuster, Catherine, Mailly, Laurent, Baumert, Thomas F.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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