A Third-Generation Lentivirus Vector with a Conditional Packaging System
Dull, T, Zufferey, R, Kelly, M, Mandel, R J, Nguyen, M, Trono, D, Naldini, L
Published in Journal of Virology (01.11.1998)
Published in Journal of Virology (01.11.1998)
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Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
Björklund, A., Kirik, D., Rosenblad, C., Georgievska, B., Lundberg, C., Mandel, R.J.
Published in Brain research (15.12.2000)
Published in Brain research (15.12.2000)
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Conference Proceeding
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
Zufferey, Romain, Nagy, Dea, Mandel, Ron J, Naldini, Luigi, Trono, Didier
Published in Nature biotechnology (01.09.1997)
Published in Nature biotechnology (01.09.1997)
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Midbrain Injection of Recombinant Adeno-Associated Virus Encoding Rat Glial Cell Line-Derived Neurotrophic Factor Protects Nigral Neurons in a Progressive 6-hydroxydopamine-Induced Degeneration Model of Parkinson's Disease in Rats
Mandel, R. J., Spratt, S. K., Snyder, R. O., Leff, S. E.
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
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Characterization of Intrastriatal Recombinant Adeno-Associated Virus-Mediated Gene Transfer of Human Tyrosine Hydroxylase and Human GTP-Cyclohydrolase I in a Rat Model of Parkinson's Disease
Mandel, R. J, Rendahl, K. G, Spratt, S. K, Snyder, R. O, Cohen, L. K, Leff, S. E
Published in The Journal of neuroscience (01.06.1998)
Published in The Journal of neuroscience (01.06.1998)
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Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways
Gombash, S E, Manfredsson, F P, Mandel, R J, Collier, T J, Fischer, D L, Kemp, C J, Kuhn, N M, Wohlgenant, S L, Fleming, S M, Sortwell, C E
Published in Gene therapy (01.07.2014)
Published in Gene therapy (01.07.2014)
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Voluntary exercise delays monogenetic obesity and overcomes reproductive dysfunction of the melanocortin-4 receptor knockout mouse
Irani, B.G., Xiang, Z., Moore, M.C., Mandel, R.J., Haskell-Luevano, C.
Published in Biochemical and biophysical research communications (21.01.2005)
Published in Biochemical and biophysical research communications (21.01.2005)
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Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration
MANDEL, R. J, GAGE, F. H, CLEVENGER, D. G, SPRATT, S. K, SNYDER, R. O, LEFF, S. E
Published in Experimental neurology (1999)
Published in Experimental neurology (1999)
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Regulation of gene expression in vivo following transduction by two separate rAAV vectors
Rendahl, Katherine G, Leff, Stuart E, Otten, Gillis R, Spratt, S. Kaye, Bohl, Delphine, Van Roey, Melinda, Donahue, Brian A, Cohen, Lawrence K, Mandel, Ronald J, Danos, Olivier, Snyder, Richard O
Published in Nature biotechnology (01.08.1998)
Published in Nature biotechnology (01.08.1998)
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Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of alpha -Synuclein in the Nigrostriatal System
Kirik, Deniz, Rosenblad, Carl, Burger, Corinna, Lundberg, Cecilia, Johansen, Teit E, Muzyczka, Nicholas, Mandel, Ronald J, Bjorklund, Anders
Published in The Journal of neuroscience (01.04.2002)
Published in The Journal of neuroscience (01.04.2002)
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Nigrostriatal α-Synucleinopathy Induced by Viral Vector-Mediated Overexpression of Human α-Synuclein: A New Primate Model of Parkinson's Disease
Kirik, Deniz, Annett, Lucy E., Burger, Corinna, Muzyczka, Nicholas, Mandel, Ronald J., Björklund, Anders
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.2003)
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Characterization of gaba release from intrastriatal striatal transplants: Dependence on host-derived afferents
Campbell, K., Kalén, P., Wictorin, K., Lundberg, C., Mandel, R.J., Björklund, A.
Published in Neuroscience (01.03.1993)
Published in Neuroscience (01.03.1993)
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In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase
LEFF, S. E, RENDAHL, K. G, SPRATT, S. K, KANG, U. J, MANDEL, R. J
Published in Experimental neurology (01.06.1998)
Published in Experimental neurology (01.06.1998)
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Journal Article
Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery
Zufferey, R, Dull, T, Mandel, R J, Bukovsky, A, Quiroz, D, Naldini, L, Trono, D
Published in Journal of Virology (01.12.1998)
Published in Journal of Virology (01.12.1998)
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