Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
Chang, Joan, Lucas, Morghan C, Leonte, Lidia E, Garcia-Montolio, Marc, Singh, Lukram Babloo, Findlay, Alison D, Deodhar, Mandar, Foot, Jonathan S, Jarolimek, Wolfgang, Timpson, Paul, Erler, Janine T, Cox, Thomas R
Published in Oncotarget (18.04.2017)
Published in Oncotarget (18.04.2017)
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Journal Article
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
Findlay, Alison, Turner, Craig, Schilter, Heidi, Deodhar, Mandar, Zhou, Wenbin, Perryman, Lara, Foot, Jonathan, Zahoor, Amna, Yao, Yimin, Hamilton, Ross, Brock, Mary, Raso, Christina, Stolp, Jessica, Galati, Marie, Hamprecht, Dieter, Charlton, Brett, Jarolimek, Wolfgang
Published in Clinical and translational medicine (01.11.2021)
Published in Clinical and translational medicine (01.11.2021)
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Journal Article
The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1)
Foot, Jonathan S., Deodhar, Mandar, Turner, Craig I., Yin, Ping, van Dam, Ellen M., Silva, Diego G., Olivieri, Aldo, Holt, Andrew, McDonald, Ian A.
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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Journal Article
SYNTHESIS OF SOME NEW BIHETEROCYCLES BY A ONE-POT SUZUKI-MIYAURA COUPLING REACTION
Deodhar, Mandar, Black, David StC, Chan, Daniel Shiu-Hin, Kumar, Naresh
Published in Heterocycles (01.03.2010)
Published in Heterocycles (01.03.2010)
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Journal Article
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis
Schilter, Heidi, Findlay, Alison D., Perryman, Lara, Yow, Tin T., Moses, Joshua, Zahoor, Amna, Turner, Craig I., Deodhar, Mandar, Foot, Jonathan S., Zhou, Wenbin, Greco, Angelique, Joshi, Amar, Rayner, Benjamin, Townsend, Sarah, Buson, Alberto, Jarolimek, Wolfgang
Published in Journal of cellular and molecular medicine (01.03.2019)
Published in Journal of cellular and molecular medicine (01.03.2019)
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Journal Article
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3
Findlay, Alison D, Foot, Jonathan S, Buson, Alberto, Deodhar, Mandar, Jarnicki, Andrew G, Hansbro, Philip M, Liu, Gang, Schilter, Heidi, Turner, Craig I, Zhou, Wenbin, Jarolimek, Wolfgang
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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Journal Article
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease
Foot, Jonathan S., Buson, Alberto, Deodhar, Mandar, Findlay, Alison D., Robertson, Alan D., Turner, Craig I., Yow, Tin, Zhou, Wenbin, Jarolimek, Wolfgang
Published in Bioorganic & medicinal chemistry letters (15.10.2022)
Published in Bioorganic & medicinal chemistry letters (15.10.2022)
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Journal Article
Synthesis of oxygenated 4-arylisoflavans and 4-arylflavans
Deodhar, Mandar, Wood, Kasey, Black, David StC, Kumar, Naresh
Published in Tetrahedron letters (05.12.2012)
Published in Tetrahedron letters (05.12.2012)
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Journal Article
PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo
Foot, Jonathan S, Yow, Tin T, Schilter, Heidi, Buson, Alberto, Deodhar, Mandar, Findlay, Alison D, Guo, Lily, McDonald, Ian A, Turner, Craig I, Zhou, Wenbin, Jarolimek, Wolfgang
Published in The Journal of pharmacology and experimental therapeutics (01.11.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2013)
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Journal Article
The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF- beta 1 pathway in human lung fibroblasts
Schilter, Heidi, Cantemir-Stone, Carmen Z, Leksa, Vladimir, Ohradanova-Repic, Anna, Findlay, Alison D, Deodhar, Mandar, Stockinger, Hannes, Song, Xiaomin, Molloy, Mark, Marsh, Clay B, Jarolimek, Wolfgang
Published in Immunology letters (01.06.2015)
Published in Immunology letters (01.06.2015)
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Journal Article
The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts
Schilter, Heidi, Cantemir-Stone, Carmen Z, Leksa, Vladimir, Ohradanova-Repic, Anna, Findlay, Alison D, Deodhar, Mandar, Stockinger, Hannes, Song, Xiaomin, Molloy, Mark, Marsh, Clay B, Jarolimek, Wolfgang
Published in Immunology letters (01.06.2015)
Published in Immunology letters (01.06.2015)
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Journal Article
Oxidative Dimerisation of Isoflavones: Synthesis of Kudzuisoflavone A and Related Compounds
Deodhar, Mandar, Wood, Kasey, Black, David StClair, Kumar, Naresh
Published in Australian journal of chemistry (01.01.2012)
Published in Australian journal of chemistry (01.01.2012)
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Journal Article
NOVEL SELECTIVE INHIBITORS OF LYSYL OXIDASES
HAMPRECHT, Dieter Wolfgang, JAROLIMEK, Wolfgang, DEODHAR, Mandar, FINDLAY, Alison Dorothy
Year of Publication 07.03.2024
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Year of Publication 07.03.2024
Patent
DIFLUOROHALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES, METHODS OF PREPARATION, AND USES THEREOF
MANDAR DEODHAR, ALISON DOROTHY FINDLAY, CRAIG IVAN TURNER, WOLFGANG JAROLIMEK, DIETER WOLFGANG HAMPRECHT, WENBIN ZHOU, ANGELIQUE ELSA GRECO
Year of Publication 29.11.2023
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Year of Publication 29.11.2023
Patent