Most gene fusions in cancer are stochastic events
Johansson, Bertil, Mertens, Fredrik, Schyman, Tommy, Björk, Jonas, Mandahl, Nils, Mitelman, Felix
Published in Genes chromosomes & cancer (01.09.2019)
Published in Genes chromosomes & cancer (01.09.2019)
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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Killela, Patrick J., Reitman, Zachary J., Jiao, Yuchen, Bettegowda, Chetan, Agrawal, Nishant, Diaz, Luis A., Friedman, Allan H., Friedman, Henry, Gallia, Gary L., Giovanella, Beppino C., Grollman, Arthur P., He, Tong-Chuan, He, Yiping, Hruban, Ralph H., Jallo, George I., Mandahl, Nils, Meeker, Alan K., Mertens, Fredrik, Netto, George J., Rasheed, B. Ahmed, Riggins, Gregory J., Rosenquist, Thomas A., Schiffman, Mark, Shih, Ie-Ming, Theodorescu, Dan, Torbenson, Michael S., Velculescu, Victor E., Wang, Tian-Li, Wentzensen, Nicolas, Wood, Laura D., Zhang, Ming, McLendon, Roger E., Bigner, Darell D., Kinzler, Kenneth W., Vogelstein, Bert, Papadopoulos, Nickolas, Yan, Hai
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2013)
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Journal Article
Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor
Mohajeri, Arezoo, Tayebwa, Johnbosco, Collin, Anna, Nilsson, Jenny, Magnusson, Linda, von Steyern, Fredrik Vult, Brosjö, Otte, Domanski, Henryk A., Larsson, Olle, Sciot, Raf, Debiec-Rychter, Maria, Hornick, Jason L., Mandahl, Nils, Nord, Karolin H., Mertens, Fredrik
Published in Genes chromosomes & cancer (01.10.2013)
Published in Genes chromosomes & cancer (01.10.2013)
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Journal Article
Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
Hofvander, Jakob, Viklund, Björn, Isaksson, Anders, Brosjö, Otte, Vult von Steyern, Fredrik, Rissler, Pehr, Mandahl, Nils, Mertens, Fredrik
Published in Nature communications (10.09.2018)
Published in Nature communications (10.09.2018)
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Journal Article
Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas
Joseph, Christine G., Hwang, Heejung, Jiao, Yuchen, Wood, Laura D., Kinde, Isaac, Wu, Jian, Mandahl, Nils, Luo, Jinyong, Hruban, Ralph H., Diaz Jr, Luis A., He, Tong-Chuan, Vogelstein, Bert, Kinzler, Kenneth W., Mertens, Fredrik, Papadopoulos, Nickolas
Published in Genes chromosomes & cancer (01.01.2014)
Published in Genes chromosomes & cancer (01.01.2014)
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Journal Article
Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis
Walther, Charles, Mayrhofer, Markus, Nilsson, Jenny, Hofvander, Jakob, Jonson, Tord, Mandahl, Nils, Øra, Ingrid, Gisselsson, David, Mertens, Fredrik
Published in Genes chromosomes & cancer (01.01.2016)
Published in Genes chromosomes & cancer (01.01.2016)
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Journal Article
Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis
Gisselsson, David, Jin, Yuesheng, Lindgren, David, Persson, Johan, Gisselsson, Lennart, Hanks, Sandra, Sehic, Daniel, Mengelbier, Linda Holmquist, Øra, Ingrid, Rahman, Nazneen, Mertens, Fredrik, Mitelman, Felix, Mandahl, Nils, Klein, George
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2010)
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Journal Article
Structural and Numerical Chromosome Changes in Colon Cancer Develop through Telomere-Mediated Anaphase Bridges, Not through Mitotic Multipolarity
Stewénius, Ylva, Gorunova, Ludmila, Jonson, Tord, Larsson, Nina, Höglund, Mattias, Mandahl, Nils, Mertens, Fredrik, Mitelman, Felix, Gisselsson, David, Vogelstein, Bert
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
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Journal Article
Clinicopathologic and molecular genetic characterization of low-grade fibromyxoid sarcoma, and cloning of a novel FUS/CREB3L1 fusion gene
MERTENS, Fredrik, FLETCHER, Christopher D. M, REID, Robin, ROSAI, Juan, SCIOT, Raf, MANDAHL, Nils, PANAGOPOULOS, Ioannis, ANTONESCU, Cristina R, COINDRE, Jean-Michel, COLECCHIA, Maurizio, DOMANSKI, Henryk A, DOWNS-KELLY, Erinn, FISHER, Cyril, GOLDBLUM, John R, GUILLOU, Louis
Published in Laboratory investigation (01.03.2005)
Published in Laboratory investigation (01.03.2005)
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Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma
Nord, Karolin H., Magnusson, Linda, Isaksson, Margareth, Nilsson, Jenny, Lilljebjörn, Henrik, Domanski, Henryk A., Kindblom, Lars-Gunnar, Mandahl, Nils, Mertens, Fredrik, Rowley, Janet D.
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2010)
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Journal Article
Scattered genomic amplification in dedifferentiated liposarcoma
Mandahl, Nils, Magnusson, Linda, Nilsson, Jenny, Viklund, Björn, Arbajian, Elsa, von Steyern, Fredrik Vult, Isaksson, Anders, Mertens, Fredrik
Published in Molecular cytogenetics (24.06.2017)
Published in Molecular cytogenetics (24.06.2017)
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Journal Article
Telomere Dysfunction Triggers Extensive DNA Fragmentation and Evolution of Complex Chromosome Abnormalities in Human Malignant Tumors
Gisselsson, David, Jonson, Tord, Petersén, Åsa, Strömbeck, Bodil, Cin, Paola Dal, Höglund, Mattias, Mitelman, Felix, Mertens, Fredrik, Mandahl, Nils
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (23.10.2001)
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Journal Article
Retained Heterodisomy Is Associated with High Gene Expression in Hyperhaploid Inflammatory Leiomyosarcoma
Nord, Karolin H, Paulsson, Kajsa, Veerla, Srinivas, Wejde, Johan, Brosjö, Otte, Mandahl, Nils, Mertens, Fredrik
Published in Neoplasia (New York, N.Y.) (01.09.2012)
Published in Neoplasia (New York, N.Y.) (01.09.2012)
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Journal Article
Chromosomal Breakage-Fusion-Bridge Events Cause Genetic Intratumor Heterogeneity
Gisselsson, David, Pettersson, Louise, Hoglund, Mattias, Heidenblad, Markus, Gorunova, Ludmila, Wiegant, Joop, Mertens, Fredrik, Cin, Paola Dal, Mitelman, Felix, Mandahl, Nils
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (09.05.2000)
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Journal Article
The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma
Panagopoulos, Ioannis, Tiziana Storlazzi, Clelia, Fletcher, Christopher D.M., Fletcher, Jonathan A., Nascimento, Antonio, Domanski, Henryk A., Wejde, Johan, Brosjö, Otte, Rydholm, Anders, Isaksson, Margareth, Mandahl, Nils, Mertens, Fredrik
Published in Genes chromosomes & cancer (01.07.2004)
Published in Genes chromosomes & cancer (01.07.2004)
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Journal Article
Genomic Changes in Chromosomes 10, 16, and X in Malignant Peripheral Nerve Sheath Tumors Identify a High-Risk Patient Group
BREKKE, Helge R, RIBEIRO, Franclim R, MANDAHL, Nils, SMELAND, Sigbjørn, MERTENS, Fredrik, SKOTHEIM, Rolf I, LOTHE, Ragnhild A, KOLBERG, Matthias, AGESEN, Trude H, LIND, Guro E, EKNOES, Mette, HALL, Kirsten S, BJERKEHAGEN, Bodil, VAN DEN BERG, Eva, TEIXEIRA, Manuel R
Published in Journal of clinical oncology (20.03.2010)
Published in Journal of clinical oncology (20.03.2010)
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Journal Article
Genomic Profiling of Chondrosarcoma: Chromosomal Patterns in Central and Peripheral Tumors
HALLOR, Karolin H, STAAF, Johan, VULT VON STEYERN, Fredrik, JONSSON, Kjell, SKORPIL, Mikael, MANDAHL, Nils, MERTENS, Fredrik, BOVEE, Judith V. M. G, HOGENDOORN, Pancras C. W, CLETON-JANSEN, Anne-Marie, KNUUTILA, Sakari, SAVOLA, Suvi, NIINI, Tarja, BROSJÖ, Otte, BAUER, Henrik C. F
Published in Clinical cancer research (15.04.2009)
Published in Clinical cancer research (15.04.2009)
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Journal Article
Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera
Panagopoulos, Ioannis, Möller, Emely, Dahlén, Anna, Isaksson, Margareth, Mandahl, Nils, Vlamis-Gardikas, Alexios, Mertens, Fredrik
Published in Genes chromosomes & cancer (01.02.2007)
Published in Genes chromosomes & cancer (01.02.2007)
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