CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.
Published in Blood (06.08.2015)
Published in Blood (06.08.2015)
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Journal Article
The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
Lu, Ling, Payvandi, Faribourz, Wu, Lei, Zhang, Ling-Hua, Hariri, Robert J, Man, Hon-Wah, Chen, Roger S., Muller, George W., Hughes, Christopher C.W., Stirling, David I., Schafer, Peter H., Bartlett, J. Blake
Published in Microvascular research (01.03.2009)
Published in Microvascular research (01.03.2009)
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Journal Article
Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity
Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
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Journal Article
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Matyskiela, Mary E, Zhang, Weihong, Man, Hon-Wah, Muller, George, Khambatta, Godrej, Baculi, Frans, Hickman, Matthew, LeBrun, Laurie, Pagarigan, Barbra, Carmel, Gilles, Lu, Chin-Chun, Lu, Gang, Riley, Mariko, Satoh, Yoshitaka, Schafer, Peter, Daniel, Thomas O, Carmichael, James, Cathers, Brian E, Chamberlain, Philip P
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Journal Article
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
Ruchelman, Alexander L., Man, Hon-Wah, Chen, Roger, Liu, Wei, Lu, Ling, Cedzik, Dorota, Zhang, Ling, Leisten, Jim, Collette, Alice, Narla, Rama Krishna, Raymon, Heather K., Muller, George W.
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
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Journal Article
Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs
Schafer, Peter H, Gandhi, Anita K, Loveland, Michelle A, Chen, Roger S, Man, Hon-Wah, Schnetkamp, Paul P M, Wolbring, Gregor, Govinda, Sowmya, Corral, Laura G, Payvandi, Faribourz, Muller, George W, Stirling, David I
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
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Journal Article
Protein Degradation via CRL4(CRBN) Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D., Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Journal Article
Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor
MAN, Hon-Wah, SCHAFER, Peter, BABUSIS, Darius M, CHEN, Roger, STIRLING, Dave, MULLER, George W, LU MIN WONG, PATTERSON, Rebecca T, CORRAL, Laura G, RAYMON, Heather, BLEASE, Kate, LEISTEN, Jim, SHIRLEY, Michael A, YANG TANG
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Journal Article
Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry
Matteson, Donald S, Man, Hon-Wah, Ho, Oliver C
Published in Journal of the American Chemical Society (15.05.1996)
Published in Journal of the American Chemical Society (15.05.1996)
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Journal Article
Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies
Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan
Published in Journal of medicinal chemistry (23.04.1998)
Published in Journal of medicinal chemistry (23.04.1998)
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Journal Article
Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues
PREHN, John L, LANDERS, Carol, MULLER, George W, MAN, Hon-Wah, STIRLING, David I, TARGAN, Stephan R
Published in Journal of clinical immunology (01.09.2001)
Published in Journal of clinical immunology (01.09.2001)
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Journal Article
Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
Chung, Francisco, Palmer, Brian D, Muller, George W, Man, Hon-Wah, Kestell, Phillip, Baguley, Bruce C, Ching, Lai-Ming
Published in Oncology research (2003)
Published in Oncology research (2003)
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Journal Article
Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells
Mouratidis, Petros X E, Colston, Kay W, Bartlett, Jake Blake, Muller, George W, Man, Hon-Wah, Stirling, David, Dalgleish, Angus G
Published in Pancreas (01.01.2009)
Published in Pancreas (01.01.2009)
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Journal Article
α-Fluoro-substituted thalidomide analogues
MAN, Hon-Wah, CORRAL, Laura G, STIRLING, David I, MULLER, George W
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Journal Article
A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins
MARRIOTT, J. Blake, CLARKE, Ian A, DALGLEISH, Angus G, CZAJKA, Anna, DREDGE, Keith, CHILDS, Kay, MAN, Hon-Wah, SCHAFER, Peter, GOVINDA, Sowmya, MULLER, George W, STIRLING, David I
Published in Cancer research (Chicago, Ill.) (01.02.2003)
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Published in Cancer research (Chicago, Ill.) (01.02.2003)
Journal Article
(S)-4--3-플루오로벤조니트릴을 포함하는 고체 형태 및 이의 염, 그리고 이를 포함하는 조성물 및 이의 사용 방법
FERRETTI ANTONIO C, JAIN UDAYKUMAR, HUANG LIANFENG, TAVARES GRECO PAULA A, WU WENJU, ARTMAN III GERALD D, YIN ZHIWEI, TSOU NANCY NIENHUA, MAN HON WAH
Year of Publication 18.10.2021
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Year of Publication 18.10.2021
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