Search Results - "MAN, Hon-wah" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

by Hagner, Patrick R., Man, Hon-Wah, Fontanillo, Celia, Wang, Maria, Couto, Suzana, Breider, Mike, Bjorklund, Chad, Havens, Courtney G., Lu, Gang, Rychak, Emily, Raymon, Heather, Narla, Rama Krishna, Barnes, Leo, Khambatta, Gody, Chiu, Hsiling, Kosek, Jolanta, Kang, Jian, Amantangelo, Michael D., Waldman, Michelle, Lopez-Girona, Antonia, Cai, Ti, Pourdehnad, Michael, Trotter, Matthew, Daniel, Thomas O., Schafer, Peter H., Klippel, Anke, Thakurta, Anjan, Chopra, Rajesh, Gandhi, Anita K.
Published in Blood (06.08.2015)

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The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions

The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions

by Lu, Ling, Payvandi, Faribourz, Wu, Lei, Zhang, Ling-Hua, Hariri, Robert J, Man, Hon-Wah, Chen, Roger S., Muller, George W., Hughes, Christopher C.W., Stirling, David I., Schafer, Peter H., Bartlett, J. Blake
Published in Microvascular research (01.03.2009)

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Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity

by Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.
Published in Bioorganic & medicinal chemistry letters (01.01.2013)

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A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

by Matyskiela, Mary E, Zhang, Weihong, Man, Hon-Wah, Muller, George, Khambatta, Godrej, Baculi, Frans, Hickman, Matthew, LeBrun, Laurie, Pagarigan, Barbra, Carmel, Gilles, Lu, Chin-Chun, Lu, Gang, Riley, Mariko, Satoh, Yoshitaka, Schafer, Peter, Daniel, Thomas O, Carmichael, James, Cathers, Brian E, Chamberlain, Philip P
Published in Journal of medicinal chemistry (25.01.2018)

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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4

by Ruchelman, Alexander L., Man, Hon-Wah, Chen, Roger, Liu, Wei, Lu, Ling, Cedzik, Dorota, Zhang, Ling, Leisten, Jim, Collette, Alice, Narla, Rama Krishna, Raymon, Heather K., Muller, George W.
Published in Bioorganic & medicinal chemistry (01.11.2011)

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Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs

Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs

by Schafer, Peter H, Gandhi, Anita K, Loveland, Michelle A, Chen, Roger S, Man, Hon-Wah, Schnetkamp, Paul P M, Wolbring, Gregor, Govinda, Sowmya, Corral, Laura G, Payvandi, Faribourz, Muller, George W, Stirling, David I
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)

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Protein Degradation via CRL4(CRBN) Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Protein Degradation via CRL4(CRBN) Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

by Hansen, Joshua D., Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)

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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor

Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor

by MAN, Hon-Wah, SCHAFER, Peter, BABUSIS, Darius M, CHEN, Roger, STIRLING, Dave, MULLER, George W, LU MIN WONG, PATTERSON, Rebecca T, CORRAL, Laura G, RAYMON, Heather, BLEASE, Kate, LEISTEN, Jim, SHIRLEY, Michael A, YANG TANG
Published in Journal of medicinal chemistry (26.03.2009)

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Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry

Asymmetric Synthesis of Stegobinone via Boronic Ester Chemistry

by Matteson, Donald S, Man, Hon-Wah, Ho, Oliver C
Published in Journal of the American Chemical Society (15.05.1996)

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A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters

A Highly Enantioselective and Diastereoselective Synthesis of Cyclobutanes via Boronic Esters

by Man, Hon-Wah, Hiscox, William C, Matteson, Donald S
Published in Organic letters (12.08.1999)

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Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies

Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies

by Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan
Published in Journal of medicinal chemistry (23.04.1998)

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Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion

Enantioselective Capture and Retroracemization of (1-Bromoalkyl)boronic Esters by an N-Propanoyloxazolidinone Enolate and Iodide Ion

by Matteson, Donald S, Man, Hon-Wah
Published in Journal of organic chemistry (01.09.1994)

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Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues

Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues

by PREHN, John L, LANDERS, Carol, MULLER, George W, MAN, Hon-Wah, STIRLING, David I, TARGAN, Stephan R
Published in Journal of clinical immunology (01.09.2001)

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Journal Article

Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

by Chung, Francisco, Palmer, Brian D, Muller, George W, Man, Hon-Wah, Kestell, Phillip, Baguley, Bruce C, Ching, Lai-Ming
Published in Oncology research (2003)

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Journal Article

ISOTOPOLOGUES OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE AND METHODS OF PREPARATION THEREOF

ISOTOPOLOGUES OF 3-(5-AMINO-2-METHYL-4-OXOQUINAZOLIN-3(4H)-YL)PIPERIDINE-2,6-DIONE AND METHODS OF PREPARATION THEREOF

by WILLIAM W LEONG, MAN HON-WAH
Year of Publication 09.08.2018

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Patent

Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells

Antiproliferative effects of CC-8062 and CC-8075 in pancreatic cancer cells

by Mouratidis, Petros X E, Colston, Kay W, Bartlett, Jake Blake, Muller, George W, Man, Hon-Wah, Stirling, David, Dalgleish, Angus G
Published in Pancreas (01.01.2009)

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Journal Article

α-Fluoro-substituted thalidomide analogues

α-Fluoro-substituted thalidomide analogues

by MAN, Hon-Wah, CORRAL, Laura G, STIRLING, David I, MULLER, George W
Published in Bioorganic & medicinal chemistry letters (20.10.2003)

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A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins

by MARRIOTT, J. Blake, CLARKE, Ian A, DALGLEISH, Angus G, CZAJKA, Anna, DREDGE, Keith, CHILDS, Kay, MAN, Hon-Wah, SCHAFER, Peter, GOVINDA, Sowmya, MULLER, George W, STIRLING, David I
Published in Cancer research (Chicago, Ill.) (01.02.2003)

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4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME

4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME

by MULLER GEORG W, ALEXANDER L RUCHELMAN, MAN HON-WAH
Year of Publication 08.02.2018

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Patent

(S)-4--3-플루오로벤조니트릴을 포함하는 고체 형태 및 이의 염, 그리고 이를 포함하는 조성물 및 이의 사용 방법

(S)-4--3-플루오로벤조니트릴을 포함하는 고체 형태 및 이의 염, 그리고 이를 포함하는 조성물 및 이의 사용 방법

by FERRETTI ANTONIO C, JAIN UDAYKUMAR, HUANG LIANFENG, TAVARES GRECO PAULA A, WU WENJU, ARTMAN III GERALD D, YIN ZHIWEI, TSOU NANCY NIENHUA, MAN HON WAH
Year of Publication 18.10.2021

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Patent

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