Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity
Schafer, P.H., Parton, A., Capone, L., Cedzik, D., Brady, H., Evans, J.F., Man, H.-W., Muller, G.W., Stirling, D.I., Chopra, R.
Published in Cellular signalling (01.09.2014)
Published in Cellular signalling (01.09.2014)
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Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis
Schafer, PH, Parton, A, Gandhi, AK, Capone, L, Adams, M, Wu, L, Bartlett, JB, Loveland, MA, Gilhar, A, Cheung, Y‐F, Baillie, GS, Houslay, MD, Man, H‐W, Muller, GW, Stirling, DI
Published in British journal of pharmacology (01.02.2010)
Published in British journal of pharmacology (01.02.2010)
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Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
DREDGE, K, MARRIOTT, J. B, MACDONALD, C. D, MAN, H-W, CHEN, R, MULLER, G. W, STIRLING, D, DALGLEISH, A. G
Published in British journal of cancer (04.11.2002)
Published in British journal of cancer (04.11.2002)
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Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway
Ng, Lui, Chow, Ariel K M, Man, Johnny H W, Yau, Thomas C C, Wan, Timothy M H, Iyer, Deepak N, Kwan, Virginia H T, Poon, Ronnie T P, Pang, Roberta W C, Law, Wai-Lun
Published in BMC cancer (01.06.2018)
Published in BMC cancer (01.06.2018)
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Development of a nomogram for the estimation of long‐term adherence to clozapine therapy using neutrophil fluorescence
Man, W. H., Pérez‐Pitarch, A., Wilting, I., Heerdink, E. R., Solinge, W. W., Egberts, A. C. G., Huitema, A. D. R.
Published in British journal of clinical pharmacology (01.06.2018)
Published in British journal of clinical pharmacology (01.06.2018)
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Impact of infant pneumococcal conjugate vaccination on community acquired pneumonia hospitalization in all ages in the Netherlands
van Deursen, A.M.M., Schurink-van't Klooster, T.M., Man, W.H., van de Kassteele, J., van Gageldonk-Lafeber, A.B., Bruijning-Verhagen, P.C.J.L., de Melker, H.E., Sanders, E.A.M., Knol, M.J.
Published in Vaccine (18.12.2017)
Published in Vaccine (18.12.2017)
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Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies
Jadhav, Prabhakar K, Woerner, Francis J, Lam, Patrick Y. S, Hodge, C. Nicholas, Eyermann, Charles J, Man, Hon-Wah, Daneker, Wayne F, Bacheler, Lee T, Rayner, Marlene M, Meek, James L, Erickson-Viitanen, Susan, Jackson, David A, Calabrese, Joseph C, Schadt, Margaret, Chang, Chong-Hwan
Published in Journal of medicinal chemistry (23.04.1998)
Published in Journal of medicinal chemistry (23.04.1998)
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A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins
MARRIOTT, J. Blake, CLARKE, Ian A, DALGLEISH, Angus G, CZAJKA, Anna, DREDGE, Keith, CHILDS, Kay, MAN, Hon-Wah, SCHAFER, Peter, GOVINDA, Sowmya, MULLER, George W, STIRLING, David I
Published in Cancer research (Chicago, Ill.) (01.02.2003)
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Published in Cancer research (Chicago, Ill.) (01.02.2003)
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Preclinical analysis of the anti-tumor and anti-metastatic effects of Raf265 on colon cancer cells and CD26(+) cancer stem cells in colorectal carcinoma
Chow, Ariel K M, Cheng, Nathan S M, Lam, Colin S C, Ng, Lui, Wong, Sunny K M, Wan, Timothy M H, Man, Johnny H W, Cheung, Alvin H K, Yau, Thomas C C, Poon, Jensen T C, Law, Wai-Lun, Pang, Roberta W C
Published in Molecular cancer (11.04.2015)
Published in Molecular cancer (11.04.2015)
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Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues
PREHN, John L, LANDERS, Carol, MULLER, George W, MAN, Hon-Wah, STIRLING, David I, TARGAN, Stephan R
Published in Journal of clinical immunology (01.09.2001)
Published in Journal of clinical immunology (01.09.2001)
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Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition
GEE, Michael S, MAKONNEN, Sosina, AL-KOFAHI, Khalid, ROYSAM, Badri, PAYVANDI, Faribourz, MAN, Hon-Wah, MULLER, George W, LEE, William M. F
Published in Cancer research (Chicago, Ill.) (01.12.2003)
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Published in Cancer research (Chicago, Ill.) (01.12.2003)
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Understanding SDI; complexity and institutionalization
Erik de Man, W. H.
Published in International journal of geographical information science : IJGIS (01.03.2006)
Published in International journal of geographical information science : IJGIS (01.03.2006)
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Synthesis of 7-membered cyclic hydroxyguanidines: Novel HIV-1 protease inhibitors
Jadhav, Prabhakar K., Woerner, Francis J., Man, Hon-Wah
Published in Bioorganic & medicinal chemistry letters (09.09.1997)
Published in Bioorganic & medicinal chemistry letters (09.09.1997)
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Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
Chung, Francisco, Palmer, Brian D, Muller, George W, Man, Hon-Wah, Kestell, Phillip, Baguley, Bruce C, Ching, Lai-Ming
Published in Oncology research (2003)
Published in Oncology research (2003)
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Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3[beta]/[beta]-catenin pathway
Ng, Lui, Chow, Ariel K. M, Man, Johnny H. W, Yau, Thomas C. C, Wan, Timothy M. H, Iyer, Deepak N, Kwan, Virginia H. T, Poon, Ronnie T. P, Pang, Roberta W. C, Law, Wai-Lun
Published in BMC cancer (01.06.2018)
Published in BMC cancer (01.06.2018)
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Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs
Schafer, Peter H, Gandhi, Anita K, Loveland, Michelle A, Chen, Roger S, Man, Hon-Wah, Schnetkamp, Paul P M, Wolbring, Gregor, Govinda, Sowmya, Corral, Laura G, Payvandi, Faribourz, Muller, George W, Stirling, David I
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
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