Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine
Malysz, John, Gibbons, Simon J, Saravanaperumal, Siva A, Du, Peng, Eisenman, Seth T, Cao, Chike, Oh, Uhtaek, Saur, Dieter, Klein, Sabine, Ordog, Tamas, Farrugia, Gianrico
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2017)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2017)
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Journal Article
Distinct Profiles of α7 nAChR Positive Allosteric Modulation Revealed by Structurally Diverse Chemotypes
Halvard Grønlien, Jens, Håkerud, Monika, Ween, Hilde, Thorin-Hagene, Kirsten, Briggs, Clark A., Gopalakrishnan, Murali, Malysz, John
Published in Molecular pharmacology (01.09.2007)
Published in Molecular pharmacology (01.09.2007)
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Journal Article
An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
Timmermann, Daniel B., Grønlien, Jens Halvard, Kohlhaas, Kathy L., Nielsen, Elsebet Ø., Dam, Eva, Jørgensen, Tino D., Ahring, Philip K., Peters, Dan, Holst, Dorte, Chrsitensen, Jeppe K., Malysz, John, Briggs, Clark A., Gopalakrishnan, Murali, Olsen, Gunnar M.
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
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Journal Article
Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function
Hristov, Kiril L, Smith, Amy C, Parajuli, Shankar P, Malysz, John, Rovner, Eric S, Petkov, Georgi V
Published in American Journal of Physiology: Cell Physiology (01.04.2016)
Published in American Journal of Physiology: Cell Physiology (01.04.2016)
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Journal Article
Differential effects of TRPM4 channel inhibitors on Guinea pig urinary bladder smooth muscle excitability and contractility: Novel 4‐chloro‐2‐[2‐(2‐chloro‐phenoxy)‐acetylamino]‐benzoic acid (CBA) versus classical 9‐phenanthrol
Malysz, John, Maxwell, Sarah E., Petkov, Georgi V.
Published in Pharmacology research & perspectives (01.08.2022)
Published in Pharmacology research & perspectives (01.08.2022)
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Journal Article
Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology
Smith, Amy C, Hristov, Kiril L, Cheng, Qiuping, Xin, Wenkuan, Parajuli, Shankar P, Earley, Scott, Malysz, John, Petkov, Georgi V
Published in American Journal of Physiology: Cell Physiology (01.03.2013)
Published in American Journal of Physiology: Cell Physiology (01.03.2013)
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Journal Article
TRPM4 channel: a new player in urinary bladder smooth muscle function in rats
Smith, Amy C, Parajuli, Shankar P, Hristov, Kiril L, Cheng, Qiuping, Soder, Rupal P, Afeli, Serge A Y, Earley, Scott, Xin, Wenkuan, Malysz, John, Petkov, Georgi V
Published in American journal of physiology. Renal physiology (01.04.2013)
Published in American journal of physiology. Renal physiology (01.04.2013)
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Journal Article
Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor
Faghih, Ramin, Gopalakrishnan, Sujatha M, Gronlien, Jens Halvard, Malysz, John, Briggs, Clark A, Wetterstrand, Caroline, Ween, Hilde, Curtis, Michael P, Sarris, Kathy A, Gfesser, Gregory A, El-Kouhen, Rachid, Robb, Holly M, Radek, Richard J, Marsh, Kennan C, Bunnelle, William H, Gopalakrishnan, Murali
Published in Journal of medicinal chemistry (28.05.2009)
Published in Journal of medicinal chemistry (28.05.2009)
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Journal Article
Control of urinary bladder smooth muscle excitability by the TRPM4 channel modulator 9-phenanthrol
Parajuli, Shankar P, Hristov, Kiril L, Sullivan, Michelle N, Xin, Wenkuan, Smith, Amy C, Earley, Scott, Malysz, John, Petkov, Georgi V
Published in Channels (Austin, Tex.) (02.11.2013)
Published in Channels (Austin, Tex.) (02.11.2013)
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Journal Article
Local presentation of Steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture
Rich, Adam, Miller, Steven M, Gibbons, Simon J, Malysz, John, Szurszewski, Joseph H, Farrugia, G
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2003)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2003)
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Journal Article
Characterization of human ASIC2a homomeric channels stably expressed in murine Ltk − cells
Malysz, John, Scott, Victoria E., Faltynek, Connie, Gopalakrishnan, Murali
Published in Life sciences (1973) (02.01.2008)
Published in Life sciences (1973) (02.01.2008)
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Journal Article
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity
Hulzinga, Jan D, Thuneberg, Lars, Klüppel, Michael, Malysz, John, Mikkelsen, Hanne B, Bernstein, Alan
Published in Nature (London) (26.01.1995)
Published in Nature (London) (26.01.1995)
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Journal Article
Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle
Malysz, John, Buckner, Steven A, Daza, Anthony V, Milicic, Ivan, Perez-Medrano, Arturo, Gopalakrishnan, Murali
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.05.2004)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.05.2004)
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