GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy
Kasiewicz, Lisa N., Biswas, Souvik, Beach, Aaron, Ren, Huilan, Dutta, Chaitali, Mazzola, Anne Marie, Rohde, Ellen, Chadwick, Alexandra, Cheng, Christopher, Garcia, Sara P., Iyer, Sowmya, Matsumoto, Yuri, Khera, Amit V., Musunuru, Kiran, Kathiresan, Sekar, Malyala, Padma, Rajeev, Kallanthottathil G., Bellinger, Andrew M.
Published in Nature communications (15.05.2023)
Published in Nature communications (15.05.2023)
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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Sharp, Fiona A, Ruane, Darren, Claass, Benjamin, Creagh, Emma, Harris, James, Malyala, Padma, Singh, Manomohan, O'Hagan, Derek T, Pétrilli, Virginie, Tschopp, Jurg, O'Neill, Luke A.J, Lavelle, Ed C
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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Rational design of small molecules as vaccine adjuvants
Wu, Tom Y-H, Singh, Manmohan, Miller, Andrew T, De Gregorio, Ennio, Doro, Francesco, D'Oro, Ugo, Skibinski, David A G, Mbow, M Lamine, Bufali, Simone, Herman, Ann E, Cortez, Alex, Li, Yongkai, Nayak, Bishnu P, Tritto, Elaine, Filippi, Christophe M, Otten, Gillis R, Brito, Luis A, Monaci, Elisabetta, Li, Chun, Aprea, Susanna, Valentini, Sara, Calabrό, Samuele, Laera, Donatello, Brunelli, Brunella, Caproni, Elena, Malyala, Padma, Panchal, Rekha G, Warren, Travis K, Bavari, Sina, O'Hagan, Derek T, Cooke, Michael P, Valiante, Nicholas M
Published in Science translational medicine (19.11.2014)
Published in Science translational medicine (19.11.2014)
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Journal Article
Enhancing the therapeutic efficacy of CpG oligonucleotides using biodegradable microparticles
Malyala, Padma, O'Hagan, Derek T., Singh, Manmohan
Published in Advanced drug delivery reviews (28.03.2009)
Published in Advanced drug delivery reviews (28.03.2009)
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Journal Article
Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs
Francica, Joseph R., Zak, Daniel E., Linde, Caitlyn, Siena, Emilio, Johnson, Carrie, Juraska, Michal, Yates, Nicole L., Gunn, Bronwyn, De Gregorio, Ennio, Flynn, Barbara J., Valiante, Nicholas M., Malyala, Padma, Barnett, Susan W., Sarkar, Pampi, Singh, Manmohan, Jain, Siddhartha, Ackerman, Margaret, Alam, Munir, Ferrari, Guido, Salazar, Andres, Tomaras, Georgia D., O'Hagan, Derek T., Aderem, Alan, Alter, Galit, Seder, Robert A.
Published in Blood advances (28.11.2017)
Published in Blood advances (28.11.2017)
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Journal Article
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Musunuru, Kiran, Chadwick, Alexandra C., Mizoguchi, Taiji, Garcia, Sara P., DeNizio, Jamie E., Reiss, Caroline W., Wang, Kui, Iyer, Sowmya, Dutta, Chaitali, Clendaniel, Victoria, Amaonye, Michael, Beach, Aaron, Berth, Kathleen, Biswas, Souvik, Braun, Maurine C., Chen, Huei-Mei, Colace, Thomas V., Ganey, John D., Gangopadhyay, Soumyashree A., Garrity, Ryan, Kasiewicz, Lisa N., Lavoie, Jennifer, Madsen, James A., Matsumoto, Yuri, Mazzola, Anne Marie, Nasrullah, Yusuf S., Nneji, Joseph, Ren, Huilan, Sanjeev, Athul, Shay, Madeleine, Stahley, Mary R., Fan, Steven H. Y., Tam, Ying K., Gaudelli, Nicole M., Ciaramella, Giuseppe, Stolz, Leslie E., Malyala, Padma, Cheng, Christopher J., Rajeev, Kallanthottathil G., Rohde, Ellen, Bellinger, Andrew M., Kathiresan, Sekar
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Journal Article
CMC Regulatory Considerations for Antibody-Drug Conjugates
Bechtold-Peters, Karoline, Ruggiero, Andrea, Vriezen, Nienke, Ihle, Nathan, Klein, Armin, Morgan, Charles, Schweizer, Daniel, Liu, Dengfeng, Jacobson, Fred, Buecheler, Jakob, Panek, Mark, Duggan, Naomi, Malyala, Padma, Dupraz, Philippe, Desai, Priyanka, Niu, Shufang, Feng, Yiqing, Wang, Xiangyang
Published in Journal of pharmaceutical sciences (01.12.2023)
Published in Journal of pharmaceutical sciences (01.12.2023)
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Journal Article
The Preparation and Physicochemical Characterization of Aluminum Hydroxide/TLR7a, a Novel Vaccine Adjuvant Comprising a Small Molecule Adsorbed to Aluminum Hydroxide
Malyala, Padma, Laera, Donatello, Cianetti, Simona, Bufali, Simone, Aggravi, Marianna, Ianni, Elvira, Judge, Casey, Otten, Gillis, Singh, Manmohan, O'Hagan, Derek T.
Published in Journal of pharmaceutical sciences (01.06.2018)
Published in Journal of pharmaceutical sciences (01.06.2018)
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Journal Article
Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines
Buonsanti, Cecilia, Balocchi, Cristiana, Harfouche, Carole, Corrente, Federica, Galli Stampino, Luisa, Mancini, Francesca, Tontini, Marta, Malyala, Padma, Bufali, Simone, Baudner, Barbara, De Gregorio, Ennio, Valiante, Nicholas M., O’Hagan, Derek T., Rappuoli, Rino, D’Oro, Ugo
Published in Scientific reports (21.07.2016)
Published in Scientific reports (21.07.2016)
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Journal Article
Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization
Francica, Joseph R., Sheng, Zizhang, Zhang, Zhenhai, Nishimura, Yoshiaki, Shingai, Masashi, Ramesh, Akshaya, Keele, Brandon F., Schmidt, Stephen D., Flynn, Barbara J., Darko, Sam, Lynch, Rebecca M., Yamamoto, Takuya, Matus-Nicodemos, Rodrigo, Wolinsky, David, Nason, Martha, Valiante, Nicholas M., Malyala, Padma, De Gregorio, Ennio, Barnett, Susan W., Singh, Manmohan, O’Hagan, Derek T., Koup, Richard A., Mascola, John R., Martin, Malcolm A., Kepler, Thomas B., Douek, Daniel C., Shapiro, Lawrence, Seder, Robert A.
Published in Nature communications (10.04.2015)
Published in Nature communications (10.04.2015)
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Journal Article
표적화된 RNA 전달을 위한 조성물 및 방법
KASIEWICZ LISA N, BISWAS SOUVIK, RAJEEV KALLANTHOTTATHIL G, REISS CAROLINE, MALYALA PADMA, CHADWICK ALEXANDRA
Year of Publication 25.01.2023
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Year of Publication 25.01.2023
Patent
Gaps in knowledge and prospects for research of adjuvanted vaccines
Seder, Robert, Reed, Steven G, O’Hagan, Derek, Malyala, Padma, D’Oro, Ugo, Laera, Donatello, Abrignani, Sergio, Cerundolo, Vincenzo, Steinman, Lawrence, Bertholet, Sylvie
Published in Vaccine (08.06.2015)
Published in Vaccine (08.06.2015)
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Journal Article
Conference Proceeding
Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant
Wen, Yingxia, Trinh, Hung V, Linton, Christine E, Tani, Chiara, Norais, Nathalie, Martinez-Guzman, DeeAnn, Ramesh, Priyanka, Sun, Yide, Situ, Frank, Karaca-Griffin, Selen, Hamlin, Christopher, Onkar, Sayali, Tian, Sai, Hilt, Susan, Malyala, Padma, Lodaya, Rushit, Li, Ning, Otten, Gillis, Palladino, Giuseppe, Friedrich, Kristian, Aggarwal, Yukti, LaBranche, Celia, Duffy, Ryan, Shen, Xiaoying, Tomaras, Georgia D, Montefiori, David C, Fulp, William, Gottardo, Raphael, Burke, Brian, Ulmer, Jeffrey B, Zolla-Pazner, Susan, Liao, Hua-Xin, Haynes, Barton F, Michael, Nelson L, Kim, Jerome H, Rao, Mangala, O'Connell, Robert J, Carfi, Andrea, Barnett, Susan W
Published in PloS one (26.04.2018)
Published in PloS one (26.04.2018)
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Journal Article
Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum‐containing adjuvants on the immune response
Hansen, Bethany, Malyala, Padma, Singh, Manmohan, Sun, Yide, Srivastava, Indresh, Hogenesch, Harm, Hem, Stanley L.
Published in Journal of pharmaceutical sciences (01.08.2011)
Published in Journal of pharmaceutical sciences (01.08.2011)
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