Novel Synthesis of the Hexahydroimidazo[1,5b]isoquinoline Scaffold: Application to the Synthesis of Glucocorticoid Receptor Modulators
Xiao, Hai-Yun, Wu, Dauh-Rurng, Malley, Mary F, Gougoutas, Jack Z, Habte, Sium F, Cunningham, Mark D, Somerville, John E, Dodd, John H, Barrish, Joel C, Nadler, Steven G, Dhar, T. G. Murali
Published in Journal of medicinal chemistry (11.02.2010)
Published in Journal of medicinal chemistry (11.02.2010)
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Discovery of Potent, Orally-Active, and Muscle-Selective Androgen Receptor Modulators Based on an N-Aryl-hydroxybicyclohydantoin Scaffold
Sun, Chongqing, Robl, Jeffrey A, Wang, Tammy C, Huang, Yanting, Kuhns, Joyce E, Lupisella, John A, Beehler, Blake C, Golla, Rajasree, Sleph, Paul G, Seethala, Ramakrishna, Fura, Aberra, Krystek, Stanley R, An, Yongmi, Malley, Mary F, Sack, John S, Salvati, Mark E, Grover, Gary J, Ostrowski, Jacek, Hamann, Lawrence G
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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Synthesis, characterization, and crystal structures of M(DO3A) (M = iron, gadolinium) and Na[M(DOTA)] (M = Fe, yttrium, Gd)
Chang, C. Allen, Francesconi, Lynn C, Malley, Mary F, Kumar, Krishan, Gougoutas, Jack Z, Tweedle, Michael F, Lee, Daniel W, Wilson, Lon J
Published in Inorganic chemistry (01.08.1993)
Published in Inorganic chemistry (01.08.1993)
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Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2
Yang, Michael G, Xiao, Zili, Zhao, Rulin, Tebben, Andrew J, Wang, Bei, Cherney, Robert J, Batt, Douglas G, Brown, Gregory D, Cvijic, Mary Ellen, Duncia, John V, Gallela, Michael A, Gardner, Daniel S, Khandelwal, Purnima, Malley, Mary F, Pang, Jian, Rose, Anne V, Santella, Joseph B, Sarjeant, Amy A, Xu, Songmei, Mathur, Arvind, Mandlekar, Sandhya, Vuppugalla, Ragini, Zhao, Qihong, Carter, Percy H
Published in ACS medicinal chemistry letters (10.06.2021)
Published in ACS medicinal chemistry letters (10.06.2021)
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Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672
Yang, Michael G, Xiao, Zili, Cherney, Robert J, Tebben, Andrew J, Batt, Douglas G, Brown, Gregory D, Chen, Jing, Cvijic, Mary Ellen, Dabros, Marta, Duncia, John V, Galella, Michael, Gardner, Daniel S, Khandelwal, Purnima, Ko, Soo S, Malley, Mary F, Mo, Ruowei, Pang, Jian, Rose, Anne V, Santella, Joseph B, Shi, Hong, Srivastava, Anurag, Traeger, Sarah C, Wang, Bei, Xu, Songmei, Zhao, Rulin, Barrish, Joel C, Mandlekar, Sandhya, Zhao, Qihong, Carter, Percy H
Published in ACS medicinal chemistry letters (14.03.2019)
Published in ACS medicinal chemistry letters (14.03.2019)
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Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents
Rovnyak, George C, Atwal, Karnail S, Hedberg, Anders, Kimball, S. David, Moreland, Suzanne, Gougoutas, Jack Z, O'Reilly, Brian C, Schwartz, Joseph, Malley, Mary F
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
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Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists
Sheppeck, James E., Gilmore, John L., Xiao, Hai-Yun, Dhar, T.G. Murali, Nirschl, David, Doweyko, Arthur M., Sack, Jack S., Corbett, Martin J., Malley, Mary F., Gougoutas, Jack Z., Mckay, Lorraine, Cunningham, Mark D., Habte, Sium F., Dodd, John H., Nadler, Steven G., Somerville, John E., Barrish, Joel C.
Published in Bioorganic & medicinal chemistry letters (01.10.2013)
Published in Bioorganic & medicinal chemistry letters (01.10.2013)
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Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines
Atwal, Karnail S, Rovnyak, George C, Schwartz, Joseph, Moreland, Suzanne, Hedberg, Anders, Gougoutas, Jack Z, Malley, Mary F, Floyd, David M
Published in Journal of medicinal chemistry (01.05.1990)
Published in Journal of medicinal chemistry (01.05.1990)
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Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors
Lin, Shuqun, Wrobleski, Stephen T., Hynes, John, Pitt, Sidney, Zhang, Rosemary, Fan, Yi, Doweyko, Arthur M., Kish, Kevin F., Sack, John S., Malley, Mary F., Kiefer, Susan E., Newitt, John A., McKinnon, Murray, Trzaskos, James, Barrish, Joel C., Dodd, John H., Schieven, Gary L., Leftheris, Katerina
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
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Characterization of NADP + binding to perdeuterated MurB: backbone atom NMR assignments and chemical-shift changes
Constantine, Keith L, Mueller, Luciano, Goldfarb, Valentina, Wittekind, Michael, Metzler, William J, Yanchunas, Joseph, Robertson, James G, Malley, Mary F, Friedrichs, Mark S, Farmer, Bennett T
Published in Journal of molecular biology (18.04.1997)
Published in Journal of molecular biology (18.04.1997)
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Synthesis of Novel Potent Dipeptidyl Peptidase IV Inhibitors with Enhanced Chemical Stability: Interplay between the N-Terminal Amino Acid Alkyl Side Chain and the Cyclopropyl Group of α-Aminoacyl-l-cis-4,5-methanoprolinenitrile-Based Inhibitors
Magnin, David R, Robl, Jeffrey A, Sulsky, Richard B, Augeri, David J, Huang, Yanting, Simpkins, Ligaya M, Taunk, Prakash C, Betebenner, David A, Robertson, James G, Abboa-Offei, Benoni E, Wang, Aiying, Cap, Michael, Xin, Li, Tao, Li, Sitkoff, Doree F, Malley, Mary F, Gougoutas, Jack Z, Khanna, Ashish, Huang, Qi, Han, Song-Ping, Parker, Rex A, Hamann, Lawrence G
Published in Journal of medicinal chemistry (06.05.2004)
Published in Journal of medicinal chemistry (06.05.2004)
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Cannabinoid CB1 receptor ligand binding and function examined through mutagenesis studies of F200 and S383
Sitkoff, Doree F., Lee, Ning, Ellsworth, Bruce A., Huang, Qi, Kang, Liya, Baska, RoseAnn, Huang, Yanting, Sun, Chongqing, Pendri, Annapurna, Malley, Mary F., Scaringe, Raymond P., Gougoutas, Jack Z., Reggio, Patricia H., Ewing, William R., Pelleymounter, Mary Ann, Carlson, Kenneth E.
Published in European journal of pharmacology (25.01.2011)
Published in European journal of pharmacology (25.01.2011)
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Discovery of (R)-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a Selective, Orally Active Agonist of the 5-HT2C Receptor
Wacker, Dean A, Varnes, Jeffrey G, Malmstrom, Sarah E, Cao, Xueying, Hung, Chen-Pin, Ung, Thao, Wu, Ginger, Zhang, Ge, Zuvich, Eva, Thomas, Michael A, Keim, William J, Cullen, Mary Jane, Rohrbach, Kenneth W, Qu, Qinling, Narayanan, Rangaraj, Rossi, Karen, Janovitz, Evan, Lehman-McKeeman, Lois, Malley, Mary F, Devenny, James, Pelleymounter, Mary Ann, Miller, Keith J, Robl, Jeffrey A
Published in Journal of medicinal chemistry (22.03.2007)
Published in Journal of medicinal chemistry (22.03.2007)
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Urea based CCR3 antagonists employing a tetrahydro-1,3-oxazin-2-one spacer
Dhar, T.G. Murali, Yang, Guchen, Davies, Paul, Malley, Mary F., Gougoutas, Jack Z., Wu, Dauh-Rurng, Barrish, Joel C., Carter, Percy H.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs
Bisacchi, Gregory S, Braitman, Abbe, Cianci, Christopher W, Clark, Junius M, Field, A. Kirk, Hagen, Moira E, Hockstein, Deborah R, Malley, Mary F, Mitt, Toomas
Published in Journal of medicinal chemistry (01.04.1991)
Published in Journal of medicinal chemistry (01.04.1991)
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Novel 1,4-Homofragmentation via an α-Lactone
Godfrey, Jollie D, Fox, Rita T, Buono, Frederic G, Gougoutas, Jack Z, Malley, Mary F
Published in Journal of organic chemistry (27.10.2006)
Published in Journal of organic chemistry (27.10.2006)
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Practical synthesis of an enantiomerically pure synthon for the preparation of mevinic acid analogs
Karanewsky, Donald S, Malley, Mary F, Gougoutas, Jack Z
Published in Journal of organic chemistry (01.05.1991)
Published in Journal of organic chemistry (01.05.1991)
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Neutral, seven-coordinate dioxime complexes of technetium(III): synthesis and characterization
Linder, Karen E, Malley, Mary F, Gougoutas, Jack Z, Unger, Steve E, Nunn, Adrian D
Published in Inorganic chemistry (01.06.1990)
Published in Inorganic chemistry (01.06.1990)
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