Ubiquitin Signaling: Chemistry Comes to the Rescue
Mali, Sachitanand M, Singh, Sumeet K, Eid, Emad, Brik, Ashraf
Published in Journal of the American Chemical Society (12.04.2017)
Published in Journal of the American Chemical Society (12.04.2017)
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Journal Article
Activity‐Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α‐Globin‐Modulating Deubiquitinase
Meledin, Roman, Mali, Sachitanand M., Kleifeld, Oded, Brik, Ashraf
Published in Angewandte Chemie International Edition (14.05.2018)
Published in Angewandte Chemie International Edition (14.05.2018)
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Journal Article
The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag
Sahu, Indrajit, Mali, Sachitanand M., Sulkshane, Prasad, Xu, Cong, Rozenberg, Andrey, Morag, Roni, Sahoo, Manisha Priyadarsini, Singh, Sumeet K., Ding, Zhanyu, Wang, Yifan, Day, Sharleen, Cong, Yao, Kleifeld, Oded, Brik, Ashraf, Glickman, Michael H.
Published in Nature communications (26.10.2021)
Published in Nature communications (26.10.2021)
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Journal Article
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles
Sun, Hao, Mali, Sachitanand M., Singh, Sumeet K., Meledin, Roman, Brik, Ashraf, Kwon, Yong Tae, Kravtsova-Ivantsiv, Yelena, Bercovich, Beatrice, Ciechanover, Aaron
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
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Journal Article
Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis
Bissey, Pierre-Antoine, Mathot, Pauline, Guix, Catherine, Jasmin, Mélissa, Goddard, Isabelle, Costechareyre, Clélia, Gadot, Nicolas, Delcros, Jean-Guy, Mali, Sachitanand M, Fasan, Rudi, Arrigo, André-Patrick, Dante, Robert, Ichim, Gabriel, Mehlen, Patrick, Fombonne, Joanna
Published in Cancer research (Chicago, Ill.) (15.05.2020)
Published in Cancer research (Chicago, Ill.) (15.05.2020)
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Journal Article
Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors
Chavali, Sai Shashank, Mali, Sachitanand M., Jenkins, Jermaine L., Fasan, Rudi, Wedekind, Joseph E.
Published in The Journal of biological chemistry (04.12.2020)
Published in The Journal of biological chemistry (04.12.2020)
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Journal Article
De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains
Nawatha, Mickal, Rogers, Joseph M., Bonn, Steven M., Livneh, Ido, Lemma, Betsegaw, Mali, Sachitanand M., Vamisetti, Ganga B., Sun, Hao, Bercovich, Beatrice, Huang, Yichao, Ciechanover, Aaron, Fushman, David, Suga, Hiroaki, Brik, Ashraf
Published in Nature chemistry (01.07.2019)
Published in Nature chemistry (01.07.2019)
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Journal Article
Synthetic Uncleavable Ubiquitinated Proteins Dissect Proteasome Deubiquitination and Degradation, and Highlight Distinctive Fate of Tetraubiquitin
Singh, Sumeet K, Sahu, Indrajit, Mali, Sachitanand M, Hemantha, Hosahalli P, Kleifeld, Oded, Glickman, Michael H, Brik, Ashraf
Published in Journal of the American Chemical Society (14.12.2016)
Published in Journal of the American Chemical Society (14.12.2016)
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Journal Article
Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells
Chavali, Sai Shashank, Mali, Sachitanand M., Bonn, Rachel, Saseendran Anitha, Abhijith, Bennett, Ryan P., Smith, Harold C., Fasan, Rudi, Wedekind, Joseph E.
Published in The Journal of biological chemistry (01.12.2021)
Published in The Journal of biological chemistry (01.12.2021)
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Journal Article
Thioacids Mediated Selective and Mild N‑Acylation of Amines
Mali, Sachitanand M, Bhaisare, Rupal D, Gopi, Hosahudya N
Published in Journal of organic chemistry (07.06.2013)
Published in Journal of organic chemistry (07.06.2013)
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Journal Article
Copper(II) mediated facile and ultra fast peptide synthesis in methanol
Mali, Sachitanand M., Jadhav, Sandip V., Gopi, Hosahudya N.
Published in Chemical communications (Cambridge, England) (18.07.2012)
Published in Chemical communications (Cambridge, England) (18.07.2012)
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Journal Article
Design of Stable β‑Hairpin Mimetics through Backbone Disulfide Bonds
Ganesh Kumar, Mothukuri, Mali, Sachitanand M, Raja, K. Muruga Poopathi, Gopi, Hosahudya N
Published in Organic letters (16.01.2015)
Published in Organic letters (16.01.2015)
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Journal Article
HBTU mediated 1-hydroxybenzotriazole (HOBt) conjugate addition: synthesis and stereochemical analysis of beta-benzotriazole N-oxide substituted gamma-amino acids and hybrid peptides
Mali, Sachitanand M., Kumar, Mothukuri Ganesh, Katariya, Mona M., Gopi, Hosahudya N.
Published in Organic & biomolecular chemistry (14.11.2014)
Published in Organic & biomolecular chemistry (14.11.2014)
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Journal Article
Synthesis of alpha, beta-unsaturated gamma-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides
Mali, Sachitanand M., Bandyopadhyay, Anupam, Jadhav, Sandip V., Kumar, Mothukuri Ganesh, Gopi, Hosahudya N.
Published in Organic & biomolecular chemistry (07.10.2011)
Published in Organic & biomolecular chemistry (07.10.2011)
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Journal Article