A new antibiotic selectively kills Gram-negative pathogens
Imai, Yu, Meyer, Kirsten J., Iinishi, Akira, Favre-Godal, Quentin, Green, Robert, Manuse, Sylvie, Caboni, Mariaelena, Mori, Miho, Niles, Samantha, Ghiglieri, Meghan, Honrao, Chandrashekhar, Ma, Xiaoyu, Guo, Jason J., Makriyannis, Alexandros, Linares-Otoya, Luis, Böhringer, Nils, Wuisan, Zerlina G., Kaur, Hundeep, Wu, Runrun, Mateus, André, Typas, Athanasios, Savitski, Mikhail M., Espinoza, Josh L., O’Rourke, Aubrie, Nelson, Karen E., Hiller, Sebastian, Noinaj, Nicholas, Schäberle, Till F., D’Onofrio, Anthony, Lewis, Kim
Published in Nature (London) (01.12.2019)
Published in Nature (London) (01.12.2019)
Get full text
Journal Article
Crystal structures of agonist-bound human cannabinoid receptor CB1
Hua, Tian, Vemuri, Kiran, Nikas, Spyros P., Laprairie, Robert B., Wu, Yiran, Qu, Lu, Pu, Mengchen, Korde, Anisha, Jiang, Shan, Ho, Jo-Hao, Han, Gye Won, Ding, Kang, Li, Xuanxuan, Liu, Haiguang, Hanson, Michael A., Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie
Published in Nature (London) (27.07.2017)
Published in Nature (London) (27.07.2017)
Get full text
Journal Article
Chronic Cannabinoid Receptor 2 Activation Reverses Paclitaxel Neuropathy Without Tolerance or Cannabinoid Receptor 1–Dependent Withdrawal
Deng, Liting, Guindon, Josée, Cornett, Benjamin L, Makriyannis, Alexandros, Mackie, Ken, Hohmann, Andrea G
Published in Biological psychiatry (1969) (01.03.2015)
Published in Biological psychiatry (1969) (01.03.2015)
Get full text
Journal Article
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures
Hua, Tian, Li, Xiaoting, Wu, Lijie, Iliopoulos-Tsoutsouvas, Christos, Wang, Yuxia, Wu, Meng, Shen, Ling, Brust, Christina A., Nikas, Spyros P., Song, Feng, Song, Xiyong, Yuan, Shuguang, Sun, Qianqian, Wu, Yiran, Jiang, Shan, Grim, Travis W., Benchama, Othman, Stahl, Edward L., Zvonok, Nikolai, Zhao, Suwen, Bohn, Laura M., Makriyannis, Alexandros, Liu, Zhi-Jie
Published in Cell (20.02.2020)
Published in Cell (20.02.2020)
Get full text
Journal Article
Crystal Structure of the Human Cannabinoid Receptor CB1
Hua, Tian, Vemuri, Kiran, Pu, Mengchen, Qu, Lu, Han, Gye Won, Wu, Yiran, Zhao, Suwen, Shui, Wenqing, Li, Shanshan, Korde, Anisha, Laprairie, Robert B., Stahl, Edward L., Ho, Jo-Hao, Zvonok, Nikolai, Zhou, Han, Kufareva, Irina, Wu, Beili, Zhao, Qiang, Hanson, Michael A., Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie
Published in Cell (20.10.2016)
Published in Cell (20.10.2016)
Get full text
Journal Article
Crystal Structure of the Human Cannabinoid Receptor CB2
Li, Xiaoting, Hua, Tian, Vemuri, Kiran, Ho, Jo-Hao, Wu, Yiran, Wu, Lijie, Popov, Petr, Benchama, Othman, Zvonok, Nikolai, Locke, K’ara, Qu, Lu, Han, Gye Won, Iyer, Malliga R., Cinar, Resat, Coffey, Nathan J., Wang, Jingjing, Wu, Meng, Katritch, Vsevolod, Zhao, Suwen, Kunos, George, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie
Published in Cell (24.01.2019)
Published in Cell (24.01.2019)
Get full text
Journal Article
Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity
Tam, Joseph, Vemuri, V Kiran, Liu, Jie, Bátkai, Sándor, Mukhopadhyay, Bani, Godlewski, Grzegorz, Osei-Hyiaman, Douglas, Ohnuma, Shinobu, Ambudkar, Suresh V, Pickel, James, Makriyannis, Alexandros, Kunos, George
Published in The Journal of clinical investigation (01.08.2010)
Published in The Journal of clinical investigation (01.08.2010)
Get full text
Journal Article
Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase
Benchama, Othman, Tyukhtenko, Sergiy, Malamas, Michael S., Williams, Mark K., Makriyannis, Alexandros, Avraham, Hava Karsenty
Published in Scientific reports (29.03.2022)
Published in Scientific reports (29.03.2022)
Get full text
Journal Article
Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages
Ruiz de Azua, Inigo, Mancini, Giacomo, Srivastava, Raj Kamal, Rey, Alejandro Aparisi, Cardinal, Pierre, Tedesco, Laura, Zingaretti, Cristina Maria, Sassmann, Antonia, Quarta, Carmelo, Schwitter, Claudia, Conrad, Andrea, Wettschureck, Nina, Vemuri, V Kiran, Makriyannis, Alexandros, Hartwig, Jens, Mendez-Lago, Maria, Bindila, Laura, Monory, Krisztina, Giordano, Antonio, Cinti, Saverio, Marsicano, Giovanni, Offermanns, Stefan, Nisoli, Enzo, Pagotto, Uberto, Cota, Daniela, Lutz, Beat
Published in The Journal of clinical investigation (01.11.2017)
Published in The Journal of clinical investigation (01.11.2017)
Get full text
Journal Article
peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome
Bowles, Nicole P., Karatsoreos, Ilia N., Li, Xiaosong, Vemuri, V. Kiran, Wood, Jodi-Anne, Li, Zhiying, Tamashiro, Kellie L. K., Schwartz, Gary J., Makriyannis, Alexandros M., Kunos, George, Hillard, Cecilia J., McEwen, Bruce S., Hill, Matthew N.
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.01.2015)
Get full text
Journal Article
N-acylethanolamine-hydrolyzing acid amidase and fatty acid amide hydrolase inhibition differentially affect N-acylethanolamine levels and macrophage activation
Alhouayek, Mireille, Bottemanne, Pauline, Makriyannis, Alexandros, Muccioli, Giulio G.
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.05.2017)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.05.2017)
Get full text
Journal Article
Structural basis for activation of CB1 by an endocannabinoid analog
Krishna Kumar, Kaavya, Robertson, Michael J., Thadhani, Elina, Wang, Haoqing, Suomivuori, Carl-Mikael, Powers, Alexander S., Ji, Lipin, Nikas, Spyros P., Dror, Ron O., Inoue, Asuka, Makriyannis, Alexandros, Skiniotis, Georgios, Kobilka, Brian
Published in Nature communications (09.05.2023)
Published in Nature communications (09.05.2023)
Get full text
Journal Article
Biochemical and Proteomic Characterization of Recombinant Human α/β Hydrolase Domain 6
Shields, Christina Miyabe, Zvonok, Nikolai, Zvonok, Alexander, Makriyannis, Alexandros
Published in Scientific reports (29.01.2019)
Published in Scientific reports (29.01.2019)
Get full text
Journal Article
Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina
Papadogkonaki, Sofia, Spyridakos, Dimitris, Lapokonstantaki, Emmanouela, Chaniotakis, Nikos, Makriyannis, Alexandros, Malamas, Michael S, Thermos, Kyriaki
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
Get full text
Journal Article
N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance
Congiu, Mauro, Micheli, Laura, Santoni, Michele, Sagheddu, Claudia, Muntoni, Anna Lisa, Makriyannis, Alexandros, Malamas, Michael S., Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Pistis, Marco
Published in Neurotherapeutics (01.10.2021)
Published in Neurotherapeutics (01.10.2021)
Get full text
Journal Article
Blockade of CB1 or Activation of CB2 Cannabinoid Receptors Is Differentially Efficacious in the Treatment of the Early Pathological Events in Streptozotocin-Induced Diabetic Rats
Spyridakos, Dimitris, Mastrodimou, Niki, Vemuri, Kiran, Ho, Thanh C, Nikas, Spyros P, Makriyannis, Alexandros, Thermos, Kyriaki
Published in International journal of molecular sciences (23.12.2022)
Published in International journal of molecular sciences (23.12.2022)
Get full text
Journal Article
Correction: Eid et al. Interference with TGFβ1-Mediated Inflammation and Fibrosis Underlies Reno-Protective Effects of the CB1 Receptor Neutral Antagonists AM6545 and AM4113 in a Rat Model of Metabolic Syndrome. Molecules 2021, 26 , 866
Eid, Basma G, Neamatallah, Thikryat, Hanafy, Abeer, El-Bassossy, Hany M, Binmahfouz, Lenah, Aldawsari, Hibah M, Hasan, Atif, Abd El-Aziz, Gamal, Vemuri, Kiran, Makriyannis, Alexandros
Published in Molecules (Basel, Switzerland) (19.02.2024)
Published in Molecules (Basel, Switzerland) (19.02.2024)
Get full text
Journal Article