Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I
Cubero, Elena, Ruano, Ana, Delgado, Aida, Barril, Xavier, Morales, Sara, Trapero, Ana, Leoni, Lorenzo, Bellotto, Manolo, Maj, Roberto, Guzmán, Beatriz Calvo-Flores, Pérez-Carmona, Natalia, Garcia-Collazo, Ana Maria
Published in PloS one (20.05.2024)
Published in PloS one (20.05.2024)
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Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers
Schantl, Antonia E, Verhulst, Anja, Neven, Ellen, Behets, Geert J, D'Haese, Patrick C, Maillard, Marc, Mordasini, David, Phan, Olivier, Burnier, Michel, Spaggiari, Dany, Decosterd, Laurent A, MacAskill, Mark G, Alcaide-Corral, Carlos J, Tavares, Adriana A S, Newby, David E, Beindl, Victoria C, Maj, Roberto, Labarre, Anne, Hegde, Chrismita, Castagner, Bastien, Ivarsson, Mattias E, Leroux, Jean-Christophe
Published in Nature communications (05.02.2020)
Published in Nature communications (05.02.2020)
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Journal Article
Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer
Hayashi, Tomoko, Crain, Brian, Corr, Maripat, Chan, Michael, Cottam, Howard B, Maj, Roberto, Barberis, Alcide, Leoni, Lorenzo, Carson, Dennis A
Published in International journal of urology (01.05.2010)
Published in International journal of urology (01.05.2010)
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Journal Article
PNU-151774E protects against kainate-induced status epilepticus and hippocampal lesions in the rat
Maj, Roberto, Fariello, Ruggero G, Ukmar, Giorgio, Varasi, Mario, Pevarello, Paolo, McArthur, Robert A, Salvati, Patricia
Published in European journal of pharmacology (16.10.1998)
Published in European journal of pharmacology (16.10.1998)
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Journal Article
Brain penetrant structurally targeted allosteric regulators for treating GLB1-related disorders
Bellotto, Manolo, Maj, Roberto, García-Collazo, Ana María, Ruano, Ana, Delgado, Aida, Morales, Sara, Cubero, Elena, Pérez-Carmona, Natalia, Barril, Xavier
Published in Molecular genetics and metabolism (01.02.2020)
Published in Molecular genetics and metabolism (01.02.2020)
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A placebo-controlled efficacy study of the intravesical immunomodulators TMX-101 and TMX-202 in an orthotopic bladder cancer rat model
Falke, Johannes, Hulsbergen-van de Kaa, Christina A., Maj, Roberto, Oosterwijk, Egbert, Witjes, J. Alfred
Published in World journal of urology (01.11.2018)
Published in World journal of urology (01.11.2018)
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Journal Article
Abstract 2568: Application of novel phospholipid conjugated Toll like receptor 7 ligands for cancer therapy by topical and systemic administration
Carson, Dennis A., Hayashi, Tomoko, Crain, Brian, Yao, Shiyin, Cheng, Jeffrey, Passini, Nadia, Maj, Roberto, Mura, Emanuela, Cottam, Howard, Holldack, Johanna, Barberis, Alcide
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Monocyte targeting and activation by cationic liposomes formulated with a TLR7 agonist
Johansen, Pia T, Zucker, Daniel, Parhamifar, Ladan, Pourhassan, Houman, Madsen, Ditte Villum, Henriksen, Jonas R, Gad, Monika, Barberis, Alcide, Maj, Roberto, Andresen, Thomas L, Jensen, Simon S
Published in Expert opinion on drug delivery (01.07.2015)
Published in Expert opinion on drug delivery (01.07.2015)
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Potential of PEGylated Toll-Like Receptor 7 Ligands for Controlling Inflammation and Functional Changes in Mouse Models of Asthma and Silicosis
Ferreira, Tatiana Paula Teixeira, Mariano, Lívia Lacerda, Ghilosso-Bortolini, Roberta, de Arantes, Ana Carolina Santos, Fernandes, Andrey Junior, Berni, Michelle, Cecchinato, Valentina, Uguccioni, Mariagrazia, Maj, Roberto, Barberis, Alcide, Silva, Patricia Machado Rodrigues E, Martins, Marco Aurélio
Published in Frontiers in immunology (11.03.2016)
Published in Frontiers in immunology (11.03.2016)
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Journal Article
Inhibition of keratinocyte proliferation by phospholipid-conjugates of a TLR7 ligand in a Myc-induced hyperplastic actinic keratosis model in the absence of systemic side effects
Crain, Brian, Yao, Shiyin, Keophilaone, Vina, Promessi, Victor, Kang, McNancy, Barberis, Alcide, Maj, Roberto, Mura, Emanuela, Passini, Nadia, Holldack, Johanna, Ochoa, Ricardo, Cottam, Howard B, Carson, Dennis A, Hayashi, Tomoko
Published in EJD. European journal of dermatology (01.09.2013)
Published in EJD. European journal of dermatology (01.09.2013)
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Journal Article
Pharmacokinetics and toxicity of intravesical TMX‐101: a preclinical study in pigs
Arentsen, Harm C., Hulsbergen‐Van de Kaa, Christina A., Jansen, Cornelius F.J., Maj, Roberto, Leoni, Lorenzo M., Oosterwijk, Egbert, Witjes, J. Alfred
Published in BJU international (01.10.2011)
Published in BJU international (01.10.2011)
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Journal Article
Whole blood targeting and activation of monocytes with TLR7 agonist formulated in cationic liposomes
Jensen, Simon S, Johansen, Pia T, Zucker, Daniel, Henriksen, Jonas, Andresen, Thomas, Barberis, Alcide, Maj, Roberto, Pourhassan, Houman, Wern, Jeanette, Gad, Monika
Published in Journal for immunotherapy of cancer (07.11.2013)
Published in Journal for immunotherapy of cancer (07.11.2013)
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Journal Article
Pressor response to intravenous tyramine in healthy subjects after safinamide, a novel neuroprotectant with selective, reversible monoamine oxidase B inhibition
Cattaneo, Carlo, Caccia, Carla, Marzo, Antonio, Maj, Roberto, Fariello, Ruggero G
Published in Clinical neuropharmacology (01.07.2003)
Published in Clinical neuropharmacology (01.07.2003)
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Journal Article
Biochemical and Electrophysiological Studies on the Mechanism of Action of PNU-151774E, A Novel Antiepileptic Compound
Salvati, P, Maj, R, Caccia, C, Cervini, M A, Fornaretto, M G, Lamberti, E, Pevarello, P, Skeen, G A, White, H S, Wolf, H H, Faravelli, L, Mazzanti, M, Mancinelli, E, Varasi, M, Fariello, R G
Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1999)
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