Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine
Udler, Miriam S, McCarthy, Mark I, Florez, Jose C, Mahajan, Anubha
Published in Endocrine reviews (01.12.2019)
Published in Endocrine reviews (01.12.2019)
Get full text
Journal Article
Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases
Sanna, Serena, van Zuydam, Natalie R., Mahajan, Anubha, Kurilshikov, Alexander, Vich Vila, Arnau, Võsa, Urmo, Mujagic, Zlatan, Masclee, Ad A. M., Jonkers, Daisy M. A. E., Oosting, Marije, Joosten, Leo A. B., Netea, Mihai G., Franke, Lude, Zhernakova, Alexandra, Fu, Jingyuan, Wijmenga, Cisca, McCarthy, Mark I.
Published in Nature genetics (01.04.2019)
Published in Nature genetics (01.04.2019)
Get full text
Journal Article
Using human genetics to understand the disease impacts of testosterone in men and women
Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.
Published in Nature medicine (01.02.2020)
Published in Nature medicine (01.02.2020)
Get full text
Journal Article
Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution
Mägi, Reedik, Horikoshi, Momoko, Sofer, Tamar, Mahajan, Anubha, Kitajima, Hidetoshi, Franceschini, Nora, McCarthy, Mark I, Morris, Andrew P
Published in Human molecular genetics (15.09.2017)
Published in Human molecular genetics (15.09.2017)
Get full text
Journal Article
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
Thurner, Matthias, van de Bunt, Martijn, Torres, Jason M, Mahajan, Anubha, Nylander, Vibe, Bennett, Amanda J, Gaulton, Kyle J, Barrett, Amy, Burrows, Carla, Bell, Christopher G, Lowe, Robert, Beck, Stephan, Rakyan, Vardhman K, Gloyn, Anna L, McCarthy, Mark I
Published in eLife (07.02.2018)
Published in eLife (07.02.2018)
Get full text
Journal Article
Genome-wide association study of toxic metals and trace elements reveals novel associations
Ng, Esther, Lind, P Monica, Lindgren, Cecilia, Ingelsson, Erik, Mahajan, Anubha, Morris, Andrew, Lind, Lars
Published in Human molecular genetics (15.08.2015)
Published in Human molecular genetics (15.08.2015)
Get full text
Journal Article
Causal relationships between obesity and the leading causes of death in women and men
Censin, Jenny C, Peters, Sanne A E, Bovijn, Jonas, Ferreira, Teresa, Pulit, Sara L, Mägi, Reedik, Mahajan, Anubha, Holmes, Michael V, Lindgren, Cecilia M
Published in PLoS genetics (24.10.2019)
Published in PLoS genetics (24.10.2019)
Get full text
Journal Article
RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
Loh, Nellie Y., Minchin, James E. N., Pinnick, Katherine E., Verma, Manu, Todorčević, Marijana, Denton, Nathan, Moustafa, Julia El-Sayed, Kemp, John P., Gregson, Celia L., Evans, David M., Neville, Matt J., Small, Kerrin S., McCarthy, Mark I., Mahajan, Anubha, Rawls, John F., Karpe, Fredrik, Christodoulides, Constantinos
Published in Nature communications (03.06.2020)
Published in Nature communications (03.06.2020)
Get full text
Journal Article
Analysis of overlapping genetic association in type 1 and type 2 diabetes
Inshaw, Jamie R. J., Sidore, Carlo, Cucca, Francesco, Stefana, M. Irina, Crouch, Daniel J. M., McCarthy, Mark I., Mahajan, Anubha, Todd, John A.
Published in Diabetologia (01.06.2021)
Published in Diabetologia (01.06.2021)
Get full text
Journal Article
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults
Lu, Ling, Bennett, Derrick A, Millwood, Iona Y, Parish, Sarah, McCarthy, Mark I, Mahajan, Anubha, Lin, Xu, Bragg, Fiona, Guo, Yu, Holmes, Michael V, Afzal, Shoaib, Nordestgaard, Børge G, Bian, Zheng, Hill, Michael, Walters, Robin G, Li, Liming, Chen, Zhengming, Clarke, Robert
Published in PLoS medicine (02.05.2018)
Published in PLoS medicine (02.05.2018)
Get full text
Journal Article
Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals
Wesolowska-Andersen, Agata, Zhuo Yu, Grace, Nylander, Vibe, Abaitua, Fernando, Thurner, Matthias, Torres, Jason M, Mahajan, Anubha, Gloyn, Anna L, McCarthy, Mark I
Published in eLife (27.01.2020)
Published in eLife (27.01.2020)
Get full text
Journal Article
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
Wainberg, Michael, Mahajan, Anubha, Kundaje, Anshul, McCarthy, Mark I, Ingelsson, Erik, Sinnott-Armstrong, Nasa, Rivas, Manuel A
Published in PLoS medicine (10.12.2019)
Published in PLoS medicine (10.12.2019)
Get full text
Journal Article
The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population
Wedekind, Lauren E., Mahajan, Anubha, Hsueh, Wen-Chi, Chen, Peng, Olaiya, Muideen T., Kobes, Sayuko, Sinha, Madhumita, Baier, Leslie J., Knowler, William C., McCarthy, Mark I., Hanson, Robert L.
Published in Diabetologia (01.05.2023)
Published in Diabetologia (01.05.2023)
Get full text
Journal Article
The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians
Kim, Young Jin, Moon, Sanghoon, Hwang, Mi Yeong, Han, Sohee, Jang, Hye-Mi, Kong, Jinhwa, Shin, Dong Mun, Yoon, Kyungheon, Kim, Sung Min, Lee, Jong-Eun, Mahajan, Anubha, Park, Hyun-Young, McCarthy, Mark I., Cho, Yoon Shin, Kim, Bong-Jo
Published in Nature communications (04.11.2022)
Published in Nature communications (04.11.2022)
Get full text
Journal Article
Impact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians
CHAUHAN, Ganesh, SPURGEON, Charles J, GHOSH, Saurabh, YAJNIK, Chittaranjan S, TANDON, Nikhil, BHARADWAJ, Dwaipayan, CHANDAK, Giriraj R, TABASSUM, Rubina, BHASKAR, Seema, KULKARNI, Smita R, MAHAJAN, Anubha, CHAVALI, Sreenivas, KRANTHI KUMAR, M. V, PRAKASH, Swami, OM PRAKASH DWIVEDI
Published in Diabetes (New York, N.Y.) (01.08.2010)
Published in Diabetes (New York, N.Y.) (01.08.2010)
Get full text
Journal Article
Common variants of FTO and the risk of obesity and type 2 diabetes in Indians
Chauhan, Ganesh, Tabassum, Rubina, Mahajan, Anubha, Dwivedi, Om Prakash, Mahendran, Yuvaraj, Kaur, Ismeet, Nigam, Shubhanchi, Dubey, Himanshu, Varma, Binuja, Madhu, Sri Venkata, Mathur, Sandeep K, Ghosh, Saurabh, Tandon, Nikhil, Bharadwaj, Dwaipayan
Published in Journal of human genetics (01.10.2011)
Published in Journal of human genetics (01.10.2011)
Get full text
Journal Article
Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data
Fernández-Tajes, Juan, Gaulton, Kyle J, van de Bunt, Martijn, Torres, Jason, Thurner, Matthias, Mahajan, Anubha, Gloyn, Anna L, Lage, Kasper, McCarthy, Mark I
Published in Genome medicine (26.03.2019)
Published in Genome medicine (26.03.2019)
Get full text
Journal Article
Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives
Richardson, Tom G, Wang, Qin, Sanderson, Eleanor, Mahajan, Anubha, McCarthy, Mark I, Frayling, Timothy M, Ala-Korpela, Mika, Sniderman, Allan, Davey Smith, George, Holmes, Michael V
Published in The Lancet. Healthy longevity (01.06.2021)
Published in The Lancet. Healthy longevity (01.06.2021)
Get full text
Journal Article
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank
Gan, Wei, Walters, Robin G., Holmes, Michael V., Bragg, Fiona, Millwood, Iona Y., Banasik, Karina, Chen, Yiping, Du, Huaidong, Iona, Andri, Mahajan, Anubha, Yang, Ling, Bian, Zheng, Guo, Yu, Clarke, Robert J., Li, Liming, McCarthy, Mark I., Chen, Zhengming
Published in Diabetologia (01.07.2016)
Published in Diabetologia (01.07.2016)
Get full text
Journal Article