Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis
Mehta, Arpan R., Gregory, Jenna M., Dando, Owen, Carter, Roderick N., Burr, Karen, Nanda, Jyoti, Story, David, McDade, Karina, Smith, Colin, Morton, Nicholas M., Mahad, Don J., Hardingham, Giles E., Chandran, Siddharthan, Selvaraj, Bhuvaneish T.
Published in Acta neuropathologica (01.02.2021)
Published in Acta neuropathologica (01.02.2021)
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Journal Article
The central role of mitochondria in axonal degeneration in multiple sclerosis
Campbell, Graham R, Worrall, Joseph T, Mahad, Don J
Published in Multiple Sclerosis Journal (01.12.2014)
Published in Multiple Sclerosis Journal (01.12.2014)
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Book Review
Journal Article
Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis
Campbell, Graham R., Ziabreva, Iryna, Reeve, Amy K., Krishnan, Kim J., Reynolds, Richard, Howell, Owen, Lassmann, Hans, Turnbull, Doug M., Mahad, Don J.
Published in Annals of neurology (01.03.2011)
Published in Annals of neurology (01.03.2011)
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Journal Article
Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons
Ohno, Nobuhiko, Chiang, Hao, Mahad, Don J., Kidd, Grahame J., Liu, LiPing, Ransohoff, Richard M., Sheng, Zu-Hang, Komuro, Hitoshi, Trapp, Bruce D.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
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Journal Article
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis
Licht-Mayer, Simon, Campbell, Graham R., Canizares, Marco, Mehta, Arpan R., Gane, Angus B., McGill, Katie, Ghosh, Aniket, Fullerton, Alexander, Menezes, Niels, Dean, Jasmine, Dunham, Jordon, Al-Azki, Sarah, Pryce, Gareth, Zandee, Stephanie, Zhao, Chao, Kipp, Markus, Smith, Kenneth J., Baker, David, Altmann, Daniel, Anderton, Stephen M., Kap, Yolanda S., Laman, Jon D., Hart, Bert A.‘t, Rodriguez, Moses, Watzlawick, Ralf, Schwab, Jan M., Carter, Roderick, Morton, Nicholas, Zagnoni, Michele, Franklin, Robin J. M., Mitchell, Rory, Fleetwood-Walker, Sue, Lyons, David A., Chandran, Siddharthan, Lassmann, Hans, Trapp, Bruce D., Mahad, Don J.
Published in Acta neuropathologica (01.08.2020)
Published in Acta neuropathologica (01.08.2020)
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Journal Article
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis
Zambonin, Jessica L., Zhao, Chao, Ohno, Nobuhiko, Campbell, Graham R., Engeham, Sarah, Ziabreva, Iryna, Schwarz, Nadine, Lee, Sok Ee, Frischer, Josa M., Turnbull, Doug M., Trapp, Bruce D., Lassmann, Hans, Franklin, Robin J. M., Mahad, Don J.
Published in Brain (London, England : 1878) (01.07.2011)
Published in Brain (London, England : 1878) (01.07.2011)
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Journal Article
Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis
Dunham, Jordon, Bauer, Jan, Campbell, Graham R, Mahad, Don J, van Driel, Nikki, van der Pol, Susanne M A, ‘t Hart, Bert A, Lassmann, Hans, Laman, Jon D, van Horssen, Jack, Kap, Yolanda S
Published in Journal of neuropathology and experimental neurology (01.06.2017)
Published in Journal of neuropathology and experimental neurology (01.06.2017)
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Journal Article
Human Cerebrospinal Fluid Central Memory CD4+T Cells: Evidence for Trafficking through Choroid Plexus and Meninges via P-Selectin
Kivisäkk, Pia, Mahad, Don J., Callahan, Melissa K., Trebst, Corinna, Tucky, Barbara, Wei, Tao, Wu, Lijun, Baekkevold, Espen S., Lassmann, Hans, Staugaitis, Susan M., Campbell, James J., Ransohoff, Richard M.
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2003)
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Journal Article
Clonal expansion of mitochondrial DNA deletions and the progression of multiple sclerosis
Campbell, Graham R, Mahad, Don J
Published in CNS & neurological disorders drug targets (01.08.2012)
Published in CNS & neurological disorders drug targets (01.08.2012)
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Journal Article
Expression of CCR7 in multiple sclerosis: Implications for CNS immunity
Kivisäkk, Pia, Mahad, Don J., Callahan, Melissa K., Sikora, Keith, Trebst, Corinna, Tucky, Barbara, Wujek, Jerome, Ravid, Rivka, Staugaitis, Susan M., Lassmann, Hans, Ransohoff, Richard M.
Published in Annals of neurology (01.05.2004)
Published in Annals of neurology (01.05.2004)
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Journal Article
Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis
Campbell, Graham R., Kraytsberg, Yevgenya, Krishnan, Kim J., Ohno, Nobuhiko, Ziabreva, Iryna, Reeve, Amy, Trapp, Bruce D., Newcombe, Jia, Reynolds, Richard, Lassmann, Hans, Khrapko, Konstantin, Turnbull, Doug M., Mahad, Don J.
Published in Acta neuropathologica (01.08.2012)
Published in Acta neuropathologica (01.08.2012)
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Journal Article
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects
Klotz, Luisa, Eschborn, Melanie, Lindner, Maren, Liebmann, Marie, Herold, Martin, Janoschka, Claudia, Torres Garrido, Belén, Schulte-Mecklenbeck, Andreas, Gross, Catharina C, Breuer, Johanna, Hundehege, Petra, Posevitz, Vilmos, Pignolet, Béatrice, Nebel, Giulia, Glander, Shirin, Freise, Nicole, Austermann, Judith, Wirth, Timo, Campbell, Graham R, Schneider-Hohendorf, Tilman, Eveslage, Maria, Brassat, David, Schwab, Nicholas, Loser, Karin, Roth, Johannes, Busch, Karin B, Stoll, Monika, Mahad, Don J, Meuth, Sven G, Turner, Timothy, Bar-Or, Amit, Wiendl, Heinz
Published in Science translational medicine (01.05.2019)
Published in Science translational medicine (01.05.2019)
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Journal Article
Mitochondrial changes within axons in multiple sclerosis
Mahad, Don J., Ziabreva, Iryna, Campbell, Graham, Lax, Nichola, White, Katherine, Hanson, Peter S., Lassmann, Hans, Turnbull, Douglass M.
Published in Brain (London, England : 1878) (01.05.2009)
Published in Brain (London, England : 1878) (01.05.2009)
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Journal Article
Expression of Chemokine Receptors CCR1 and CCR5 Reflects Differential Activation of Mononuclear Phagocytes in Pattern II and Pattern III Multiple Sclerosis Lesions
MAHAD, DON J, TREBST, CORINNA, KIVISÄKK, PIA, STAUGAITIS, SUSAN M, TUCKY, BARBARA, WEI, TAO, LUCCHINETTI, CLAUDIA F, LASSMANN, HANS, RANSOHOFF, RICHARD M
Published in Journal of neuropathology and experimental neurology (01.03.2004)
Published in Journal of neuropathology and experimental neurology (01.03.2004)
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Journal Article
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
Licht‐Mayer, Simon, Campbell, Graham R., Mehta, Arpan R., McGill, Katie, Symonds, Alex, Al‐Azki, Sarah, Pryce, Gareth, Zandee, Stephanie, Zhao, Chao, Kipp, Markus, Smith, Kenneth J., Baker, David, Altmann, Daniel, Anderton, Stephen M., Kap, Yolanda S., Laman, Jon D., 't Hart, Bert A., Rodriguez, Moses, Franklin, Robin J. M., Chandran, Siddharthan, Lassmann, Hans, Trapp, Bruce D., Mahad, Don J.
Published in Neuropathology and applied neurobiology (01.02.2023)
Published in Neuropathology and applied neurobiology (01.02.2023)
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