Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors
Corbett, Jeffrey W, Ko, Soo S, Rodgers, James D, Gearhart, Lisa A, Magnus, Nicholas A, Bacheler, Lee T, Diamond, Sharon, Jeffrey, Susan, Klabe, Ronald M, Cordova, Beverly C, Garber, Sena, Logue, Kelly, Trainor, George L, Anderson, Paul S, Erickson-Viitanen, Susan K
Published in Journal of medicinal chemistry (18.05.2000)
Published in Journal of medicinal chemistry (18.05.2000)
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Journal Article
An Efficient Chiral Moderator Prepared from Inexpensive (+)-3-Carene: Synthesis of the HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor DPC 963
Kauffman, Goss S, Harris, Gregory D, Dorow, Roberta L, Stone, Benjamin R. P, Parsons, Rodney L, Pesti, Jaan A, Magnus, Nicholas A, Fortunak, Joseph M, Confalone, Pat N, Nugent, William A
Published in Organic letters (05.10.2000)
Published in Organic letters (05.10.2000)
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Journal Article
Optimized Catalytic Enantioselective Aryl Transfer Process Gives Access to mGlu2 Receptor Potentiators
Magnus, Nicholas A, Anzeveno, Peter B, Coffey, D. Scott, Hay, David A, Laurila, Michael E, Schkeryantz, Jeffrey M, Shaw, Bruce W, Staszak, Michael A
Published in Organic process research & development (01.05.2007)
Published in Organic process research & development (01.05.2007)
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Journal Article
Cyclization of Methyl-Coumalate-Derived Methyl 1‑Benzamido-6-oxo-1,6-dihydropyridine-3-carboxylates: Assembly of the [1,2,4]Triazolo[1,5‑a]pyridine Ring System
Moloney, Harold, Magnus, Nicholas A, Buser, Jonas Y, Embry, Matthew C
Published in Journal of organic chemistry (16.06.2017)
Published in Journal of organic chemistry (16.06.2017)
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Journal Article
Exploring the Scope of Asymmetric Synthesis of β‑Hydroxy-γ-lactams via Noyori-type Reductions
Lynch, Denis, Deasy, Rebecca E, Clarke, Leslie-Ann, Slattery, Catherine N, Khandavilli, U. B. Rao, Lawrence, Simon E, Maguire, Anita R, Magnus, Nicholas A, Moynihan, Humphrey A
Published in Organic letters (07.10.2016)
Published in Organic letters (07.10.2016)
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Journal Article
Synthesis, Crystallization, and Biological Evaluation of an Orally Active Prodrug of Gemcitabine
Bender, David M, Bao, Jingqi, Dantzig, Anne H, Diseroad, William D, Law, Kevin L, Magnus, Nicholas A, Peterson, Jeffrey A, Perkins, Everett J, Pu, Yangwei J, Reutzel-Edens, Susan M, Remick, David M, Starling, James J, Stephenson, Gregory A, Vaid, Radhe K, Zhang, Deyi, McCarthy, James R
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Journal Article
Additives Promote Noyori-type Reductions of a β‑Keto-γ-lactam: Asymmetric Syntheses of Serotonin Norepinephrine Reuptake Inhibitors
Magnus, Nicholas A, Astleford, Bret A, Laird, Dana L. T, Maloney, Todd D, McFarland, Adam D, Rizzo, John R, Ruble, J. Craig, Stephenson, Gregory A, Wepsiec, James P
Published in Journal of organic chemistry (07.06.2013)
Published in Journal of organic chemistry (07.06.2013)
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Journal Article
Synthesis of an ORL‑1 Receptor Antagonist via a Radical Bromination and Deoxyfluorination to Afford a gem-Difluorospirocycle
DeBaillie, Amy C, Jones, Chauncey D, Magnus, Nicholas A, Mateos, Carlos, Torrado, Alicia, Wepsiec, James P, Tokala, Ramachandar, Raje, Prasad
Published in Organic process research & development (20.11.2015)
Published in Organic process research & development (20.11.2015)
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Journal Article
Diastereomeric Salt Resolution Based Synthesis of LY503430, an AMPA (α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid) Potentiator
Magnus, Nicholas A, Aikins, James A, Cronin, Jason S, Diseroad, William D, Hargis, Amy D, LeTourneau, Michael E, Parker, Bruce E, Reutzel-Edens, Susan M, Schafer, John P, Staszak, Michael A, Stephenson, Gregory A, Tameze, Shella L, Zollars, Lisa M. H
Published in Organic process research & development (01.09.2005)
Published in Organic process research & development (01.09.2005)
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Leveraging an Industrial–Academic Partnership To Optimize Small Molecule Process Development within the Pharmaceutical Industry
Deasy, Rebecca E, Slattery, Catherine N, Kissane, Marie, McNamara, Orla A, Lynch, Denis, Maguire, Anita R, Moynihan, Humphrey A, O’Keeffe, Sarah, Kopach, Michael E, Mitchell, David, Magnus, Nicholas A, Kjell, Douglas P, Moher, Eric D
Published in Organic process research & development (20.02.2015)
Published in Organic process research & development (20.02.2015)
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Journal Article
Pictet−Spengler Based Synthesis of a Bisarylmaleimide Glycogen Synthase Kinase-3 Inhibitor
Magnus, Nicholas A, Ley, Christopher P, Pollock, Patrick M, Wepsiec, James P
Published in Organic letters (20.08.2010)
Published in Organic letters (20.08.2010)
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Journal Article
Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate
Laurila, Michael L, Magnus, Nicholas A, Staszak, Michael A
Published in Organic process research & development (20.11.2009)
Published in Organic process research & development (20.11.2009)
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Journal Article
Development of an Enantioselective Hydrogenation Based Synthesis of a Glucokinase Activator
Magnus, Nicholas A, Braden, Timothy M, Buser, Jonas Y, DeBaillie, Amy C, Heath, Perry C, Ley, Christopher P, Remacle, Jacob R, Varie, David L, Wilson, Thomas M
Published in Organic process research & development (18.05.2012)
Published in Organic process research & development (18.05.2012)
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Journal Article
The Development of Practical Synthetic Routes to a CB2 Agonist: Efficient Construction of a Densely Substituted Purine Core
DeBaillie, Amy C, Jones, Chauncey D, Laurila, Michael E, Magnus, Nicholas A, Staszak, Michael A
Published in Organic process research & development (15.02.2013)
Published in Organic process research & development (15.02.2013)
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Journal Article
An Asymmetric Synthesis of a Chiral Sulfone Acid with Concomitant Hydrolysis and Oxidation to Enable the Preparation of a Glucokinase Activator
DeBaillie, Amy C, Magnus, Nicholas A, Laurila, Michael E, Wepsiec, James P, Ruble, J. Craig, Petkus, Jeffrey J, Vaid, Radhe K, Niemeier, Jeffry K, Mick, Joseph F, Gunter, Thomas Z
Published in Organic process research & development (21.09.2012)
Published in Organic process research & development (21.09.2012)
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Journal Article
Synthesis of 4-Cyano Pyrroles via Mild Knorr Reactions with β-Ketonitriles
Magnus, Nicholas A, Staszak, Michael A, Udodong, Uko E, Wepsiec, James P
Published in Organic process research & development (15.09.2006)
Published in Organic process research & development (15.09.2006)
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Journal Article
Quaternary Chiral Center via Diastereoselective Enolate Amination Enables the Synthesis of an Anti-inflammatory Agent
Magnus, Nicholas A, Campagna, Silvio, Confalone, Pat N, Savage, Scott, Meloni, David J, Waltermire, Robert E, Wethman, Robert G, Yates, Mathew
Published in Organic process research & development (15.01.2010)
Published in Organic process research & development (15.01.2010)
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Journal Article
The Synthesis of a 5HT2C Receptor Agonist
Hobson, Lindsay A, Nugent, William A, Anderson, Stephen R, Deshmukh, Subodh S, Haley III, James J, Liu, Pingli, Magnus, Nicholas A, Sheeran, Patrick, Sherbine, James P, Stone, Benjamin R. P, Zhu, Jiang
Published in Organic process research & development (16.11.2007)
Published in Organic process research & development (16.11.2007)
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Journal Article
Syntheses of a Selective Peroxisome Proliferator Activated Receptor Modulator and Practical New Preparations of 2-(4-Alkoxyphenyl)ethylamines
Magnus, Nicholas A, Astleford, Bret A, Brennan, John, Stout, James R, Tharp-Taylor, Roger W
Published in Organic process research & development (20.03.2009)
Published in Organic process research & development (20.03.2009)
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