Anti-infective potential of natural products: How to develop a stronger in vitro ‘proof-of-concept’
Cos, Paul, Vlietinck, Arnold J., Berghe, Dirk Vanden, Maes, Louis
Published in Journal of ethnopharmacology (19.07.2006)
Published in Journal of ethnopharmacology (19.07.2006)
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Journal Article
Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness
Hulpia, Fabian, Mabille, Dorien, Campagnaro, Gustavo D., Schumann, Gabriela, Maes, Louis, Roditi, Isabel, Hofer, Anders, de Koning, Harry P., Caljon, Guy, Van Calenbergh, Serge
Published in Nature communications (05.12.2019)
Published in Nature communications (05.12.2019)
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Journal Article
Structural Optimization of BIPPO Analogs as Potent Antimalarials
Zheng, Yang, Matheeussen, An, Maes, Louis, Caljon, Guy, Sterk, Geert Jan, Leurs, Rob
Published in Molecules (Basel, Switzerland) (23.06.2023)
Published in Molecules (Basel, Switzerland) (23.06.2023)
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Journal Article
Impact of pulmonary African trypanosomes on the immunology and function of the lung
Mabille, Dorien, Dirkx, Laura, Thys, Sofie, Vermeersch, Marjorie, Montenye, Daniel, Govaerts, Matthias, Hendrickx, Sarah, Takac, Peter, Van Weyenbergh, Johan, Pintelon, Isabel, Delputte, Peter, Maes, Louis, Pérez-Morga, David, Timmermans, Jean-Pierre, Caljon, Guy
Published in Nature communications (18.11.2022)
Published in Nature communications (18.11.2022)
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Journal Article
Genomic and Molecular Characterization of Miltefosine Resistance in Leishmania infantum Strains with Either Natural or Acquired Resistance through Experimental Selection of Intracellular Amastigotes
Mondelaers, Annelies, Sanchez-Cañete, Maria P, Hendrickx, Sarah, Eberhardt, Eline, Garcia-Hernandez, Raquel, Lachaud, Laurence, Cotton, James, Sanders, Mandy, Cuypers, Bart, Imamura, Hideo, Dujardin, Jean-Claude, Delputte, Peter, Cos, Paul, Caljon, Guy, Gamarro, Francisco, Castanys, Santiago, Maes, Louis
Published in PloS one (28.04.2016)
Published in PloS one (28.04.2016)
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Journal Article
Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp
Brackman, Gilles, Celen, Shari, Hillaert, Ulrik, Van Calenbergh, Serge, Cos, Paul, Maes, Louis, Nelis, Hans J, Coenye, Tom
Published in PloS one (13.01.2011)
Published in PloS one (13.01.2011)
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Journal Article
Optimization and Characterization of a Galleria mellonella Larval Infection Model for Virulence Studies and the Evaluation of Therapeutics Against Streptococcus pneumoniae
Cools, Freya, Torfs, Eveline, Aizawa, Juliana, Vanhoutte, Bieke, Maes, Louis, Caljon, Guy, Delputte, Peter, Cappoen, Davie, Cos, Paul
Published in Frontiers in microbiology (21.02.2019)
Published in Frontiers in microbiology (21.02.2019)
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Journal Article
Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids
Kaiser, Marcel, Maes, Louis, Tadoori, Leela Pavan, Spangenberg, Thomas, Ioset, Jean-Robert
Published in Journal of biomolecular screening (01.06.2015)
Published in Journal of biomolecular screening (01.06.2015)
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Journal Article
Advancing drug innovation for neglected diseases-criteria for lead progression
Nwaka, Solomon, Ramirez, Bernadette, Brun, Reto, Maes, Louis, Douglas, Frank, Ridley, Robert
Published in PLoS neglected tropical diseases (25.08.2009)
Published in PLoS neglected tropical diseases (25.08.2009)
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Journal Article
In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific Differences
VERMEERSCH, Marieke, INOCENCIO DA LUZ, Raquel, TOTE, Kim, TIMMERMANS, Jean-Pierre, COS, Paul, MAES, Louis
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
Published in Antimicrobial Agents and Chemotherapy (01.09.2009)
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Journal Article
Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition
Bulté, Dimitri, Van Bockstal, Lieselotte, Dirkx, Laura, Van den Kerkhof, Magali, De Trez, Carl, Timmermans, Jean-Pierre, Hendrickx, Sarah, Maes, Louis, Caljon, Guy
Published in PLoS neglected tropical diseases (01.07.2021)
Published in PLoS neglected tropical diseases (01.07.2021)
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Journal Article
Animal models of invasive aspergillosis for drug discovery
Paulussen, Caroline, Boulet, Gaëlle A.V., Cos, Paul, Delputte, Peter, Maes, Louis J.R.M.
Published in Drug discovery today (01.09.2014)
Published in Drug discovery today (01.09.2014)
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Journal Article
Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites
Dirkx, Laura, Van Acker, Sara I, Nicolaes, Yasmine, Cunha, João Luís Reis, Ahmad, Rokaya, Hendrickx, Rik, Caljon, Ben, Imamura, Hideo, Ebo, Didier G, Jeffares, Daniel C, Sterckx, Yann G-J, Maes, Louis, Hendrickx, Sarah, Caljon, Guy
Published in PLoS pathogens (01.04.2024)
Published in PLoS pathogens (01.04.2024)
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Journal Article
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
Imamura, Hideo, Downing, Tim, Van den Broeck, Frederik, Sanders, Mandy J, Rijal, Suman, Sundar, Shyam, Mannaert, An, Vanaerschot, Manu, Berg, Maya, De Muylder, Géraldine, Dumetz, Franck, Cuypers, Bart, Maes, Ilse, Domagalska, Malgorzata, Decuypere, Saskia, Rai, Keshav, Uranw, Surendra, Bhattarai, Narayan Raj, Khanal, Basudha, Prajapati, Vijay Kumar, Sharma, Smriti, Stark, Olivia, Schönian, Gabriele, De Koning, Harry P, Settimo, Luca, Vanhollebeke, Benoit, Roy, Syamal, Ostyn, Bart, Boelaert, Marleen, Maes, Louis, Berriman, Matthew, Dujardin, Jean-Claude, Cotton, James A
Published in eLife (22.03.2016)
Published in eLife (22.03.2016)
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Journal Article
Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones
Gendron, Thibault, Lanfranchi, Don Antoine, Wenzel, Nicole I., Kessedjian, Hripsimée, Jannack, Beate, Maes, Louis, Cojean, Sandrine, Müller, Thomas J. J., Loiseau, Philippe M., Davioud-Charvet, Elisabeth
Published in Molecules (Basel, Switzerland) (04.04.2024)
Published in Molecules (Basel, Switzerland) (04.04.2024)
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Web Resource
Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity
Mowbray, Charles E, Braillard, Stéphanie, Speed, William, Glossop, Paul A, Whitlock, Gavin A, Gibson, Karl R, Mills, James E. J, Brown, Alan D, Gardner, J. Mark F, Cao, Yafeng, Hua, Wen, Morgans, Garreth L, Feijens, Pim-Bart, Matheeussen, An, Maes, Louis J
Published in Journal of medicinal chemistry (24.12.2015)
Published in Journal of medicinal chemistry (24.12.2015)
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