Sulfonamide carboxamide compounds
Van Wiltenburg, Jimmy, Shannon, Jonathan, Thom, Stephen, Macleod, Angus, St-Gallay, Stephen, Miller, David
Year of Publication 06.12.2022
Get full text
Year of Publication 06.12.2022
Patent
Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R, Braun, Matthew P, Cato, Brian P, Chambers, Mark S, O'Connor, Desmond, Cook, Susan M, Hobbs, Sarah C, Maxey, Robert, Szekeres, Helen J, Szeto, Nicola, Wafford, Keith A, MacLeod, Angus M
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Journal Article
Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2- (1-methyl-1H-1,2,4-triazol-5-ylme thoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA sub(A) alpha 5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R, Braun, Matthew P, Cato, Brian P, Chambers, Mark S, O'Connor, Desmond, Cook, Susan M, Hobbs, Sarah C, Maxey, Robert, Szekeres, Helen J, Szeto, Nicola, Wafford, Keith A, MacLeod, Angus M
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Get full text
Journal Article
Sulfonamide carboxamide compounds
MacLeod, Angus, Van Wiltenburg, Jimmy, Shannon, Jonathan, Thom, Stephen, Cooper, Matthew, St-Gallay, Stephen, Miller, David
Year of Publication 11.10.2022
Get full text
Year of Publication 11.10.2022
Patent
Pharmacokinetics and metabolism studies on (3- tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1 H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5- d][1,2,4]triazine, a functionally selective GABA A α5 inverse agonist for cognitive dysfunction
Jones, Philip, Atack, John R., Braun, Matthew P., Cato, Brian P., Chambers, Mark S., O’Connor, Desmond, Cook, Susan M., Hobbs, Sarah C., Maxey, Robert, Szekeres, Helen J., Szeto, Nicola, Wafford, Keith A., MacLeod, Angus M.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Journal Article
Pharmacokinetics and metabolism studies on 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction
JONES, Philip, ATACK, John R, SZETO, Nicola, WAFFORD, Keith A, MACLEOD, Angus M, BRAUN, Matthew P, CATO, Brian P, CHAMBERS, Mark S, O'CONNOR, Desmond, COOK, Susan M, HOBBS, Sarah C, MAXEY, Robert, SZEKERES, Helen J
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (2006)
Journal Article
Novel sulfonamide carboxamide compounds
Van Wiltenburg, Jimmy, Shannon, Jonathan, Thom, Stephen, Cooper, Matthew, Macleod, Angus, St-Gallay, Stephen, Miller, David
Year of Publication 11.08.2022
Get full text
Year of Publication 11.08.2022
Patent
Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
Van Wiltenburg, Jimmy, Shannon, Jonathan, Thom, Stephen, Cooper, Matthew, Macleod, Angus, St-Gallay, Stephen, Miller, David
Year of Publication 28.06.2022
Get full text
Year of Publication 28.06.2022
Patent
COMPOUNDS
INCERTI-PRADILLOS, Celia Amparo, SABBATANI, Juliette, COOPER, Matthew, SHANNON, Jonathan, MILLER, David, ALANINE, Thomas, THOM, Stephen, JOHNSTONE, Shawn, MACLEOD, Angus
Year of Publication 20.04.2023
Get full text
Year of Publication 20.04.2023
Patent
An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties
Chambers, Mark S, Atack, John R, Carling, Robert W, Collinson, Neil, Cook, Susan M, Dawson, Gerard R, Ferris, Pushpindar, Hobbs, Sarah C, O'connor, Desmond, Marshall, George, Rycroft, W, Macleod, Angus M
Published in Journal of medicinal chemistry (18.11.2004)
Get full text
Published in Journal of medicinal chemistry (18.11.2004)
Journal Article
An Orally Bioavailable, Functionally Selective Inverse Agonist at the Benzodiazepine Site of GABA A α5 Receptors with Cognition Enhancing Properties
Chambers, Mark S., Atack, John R., Carling, Robert W., Collinson, Neil, Cook, Susan M., Dawson, Gerard R., Ferris, Pushpindar, Hobbs, Sarah C., O'Connor, Desmond, Marshall, George, Rycroft, W., MacLeod, Angus M.
Published in Journal of medicinal chemistry (01.11.2004)
Published in Journal of medicinal chemistry (01.11.2004)
Get full text
Journal Article
NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS
Van Wiltenburg, Jimmy, Shannon, Jonathan, Thom, Stephen, Cooper, Matthew, Macleod, Angus, St-Gallay, Stephen, Miller, David
Year of Publication 15.04.2022
Get full text
Year of Publication 15.04.2022
Patent
NOVEL SULFONEUREA COMPOUNDS
SHANNON, Jonathan, ALANINE, Thomas, THOM, Stephen, CARRILLO ARREGUI, Jokin, MACLEOD, Angus
Year of Publication 07.04.2022
Get full text
Year of Publication 07.04.2022
Patent
Optical constants derivation for an inhomogeneous thin film from in situ transmission measurements
Bovard, B, Van Milligen, F J, Messerly, M J, Saxe, S G, Macleod, H A
Published in Applied optics (2004) (15.06.1985)
Published in Applied optics (2004) (15.06.1985)
Get more information
Journal Article
A new pyridazine series of GABAA alpha5 ligands
van Niel, Monique B, Wilson, Kevin, Adkins, Charles H, Atack, John R, Castro, José L, Clarke, Dawn E, Fletcher, Stephen, Gerhard, Ute, Mackey, Mark M, Malpas, Sallie, Maubach, Karen, Newman, Robert, O'Connor, Desmond, Pillai, Gopalan V, Simpson, Peter B, Thomas, Steven R, MacLeod, Angus M
Published in Journal of medicinal chemistry (22.09.2005)
Get full text
Published in Journal of medicinal chemistry (22.09.2005)
Journal Article
NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS
VAN WILTENBURG, Jimmy, ST-GALLAY, Stephen, COOPER, Matthew, SHANNON, Jonathan, MILLER, David, THOM, Stephen, MACLEOD, Angus
Year of Publication 02.02.2023
Get full text
Year of Publication 02.02.2023
Patent
A New Pyridazine Series of GABA A α5 Ligands
van Niel, Monique B., Wilson, Kevin, Adkins, Charles H., Atack, John R., Castro, José L., Clarke, Dawn E., Fletcher, Stephen, Gerhard, Ute, Mackey, Mark M., Malpas, Sallie, Maubach, Karen, Newman, Robert, O'Connor, Desmond, Pillai, Gopalan V., Simpson, Peter B., Thomas, Steven R., MacLeod, Angus M.
Published in Journal of medicinal chemistry (01.09.2005)
Published in Journal of medicinal chemistry (01.09.2005)
Get full text
Journal Article
3,4-Dihydronaphthalen-1(2H)-ones: novel ligands for the benzodiazepine site of alpha5-containing GABAA receptors
Szekeres, Helen J, Atack, John R, Chambers, Mark S, Cook, Susan M, Macaulay, Alison J, Pillai, Gopalan V, MacLeod, Angus M
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Get full text
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Journal Article