Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1
Blackaby, Wesley P, Lewis, Richard T, Thomson, Joanne L, Jennings, Andrew S. R, Goodacre, Simon C, Street, Leslie J, MacLeod, Angus M, Pike, Andrew, Wood, Suzanne, Thomas, Steve, Brown, Terry A, Smith, Alison, Pillai, Gopalan, Almond, Sarah, Guscott, Martin R, Burns, H. Donald, Eng, Waisi, Ryan, Christine, Cook, Jacquelynn, Hamill, Terence G
Published in ACS medicinal chemistry letters (14.10.2010)
Published in ACS medicinal chemistry letters (14.10.2010)
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A new class of selective, non-basic 5-HT2A receptor antagonists
LADDUWAHETTY, Tammy, BOASE, Amanda L, MITCHINSON, Andrew, QUIN, Caroline, PATEL, Smita, CHAPMAN, Kerry, MACLEOD, Angus M
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
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Fluorination of 3-(3-(Piperidin-1-yl)propyl)indoles and 3-(3-(Piperazin-1-yl)propyl)indoles Gives Selective Human 5-HT1D Receptor Ligands with Improved Pharmacokinetic Profiles
van Niel, Monique B, Collins, Ian, Beer, Margaret S, Broughton, Howard B, Cheng, Susan K. F, Goodacre, Simon C, Heald, Anne, Locker, Karen L, MacLeod, Angus M, Morrison, Denise, Moyes, Christopher R, O'Connor, Desmond, Pike, Andrew, Rowley, Michael, Russell, Michael G. N, Sohal, Balbinder, Stanton, Josephine A, Thomas, Steven, Verrier, Hugh, Watt, Alan P, Castro, José L
Published in Journal of medicinal chemistry (17.06.1999)
Published in Journal of medicinal chemistry (17.06.1999)
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4-Fluorosulfonylpiperidines: selective 5-HT2A ligands for the treatment of insomnia
Fish, L Rebecca, Gilligan, Myra T, Humphries, Alexander C, Ivarsson, Magnus, Ladduwahetty, Tammy, Merchant, Kevin J, O'Connor, Desmond, Patel, Smita, Philipps, Elisabeth, Vargas, Hugo M, Hutson, Peter H, MacLeod, Angus M
Published in Bioorganic & medicinal chemistry letters (15.08.2005)
Published in Bioorganic & medicinal chemistry letters (15.08.2005)
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A New Pyridazine Series of GABAA α5 Ligands
van Niel, Monique B, Wilson, Kevin, Adkins, Charles H, Atack, John R, Castro, José L, Clarke, Dawn E, Fletcher, Stephen, Gerhard, Ute, Mackey, Mark M, Malpas, Sallie, Maubach, Karen, Newman, Robert, O'Connor, Desmond, Pillai, Gopalan V, Simpson, Peter B, Thomas, Steven R, MacLeod, Angus M
Published in Journal of medicinal chemistry (22.09.2005)
Published in Journal of medicinal chemistry (22.09.2005)
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PREDICTORS OF INSTITUTIONALISATION IN PARKINSON'S DISEASE
Macleod, Angus, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
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MORTALITY IN PARKINSON'S DISEASE AND ATYPICAL PARKINSONIAN DISORDERS
Macleod, Angus, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
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THE PREDICTIVE VALUE OF DIFFERENT MOTOR FEATURES IN PARKINSON'S
Macleod, Angus, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
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129 Validating a new dependency measurement for parkinson’s disease
Ramsay, Neil, Macleod, Angus, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2019)
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2019)
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4-(Phenylsulfonyl)piperidines: Novel, Selective, and Bioavailable 5-HT2A Receptor Antagonists
Fletcher, Stephen R, Burkamp, Frank, Blurton, Peter, Cheng, Susan K. F, Clarkson, Robert, O'Connor, Desmond, Spinks, Daniel, Tudge, Matthew, van Niel, Monique B, Patel, Smita, Chapman, Kerry, Marwood, Rose, Shepheard, Sara, Bentley, Graham, Cook, Gina P, Bristow, Linda J, Castro, Jose L, Hutson, Peter H, MacLeod, Angus M
Published in Journal of medicinal chemistry (17.01.2002)
Published in Journal of medicinal chemistry (17.01.2002)
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6,7-Dihydro-2-benzothiophen-4(5H)-ones: A Novel Class of GABA-A α5 Receptor Inverse Agonists
Chambers, Mark S, Atack, John R, Bromidge, Frances A, Broughton, Howard B, Cook, Susan, Dawson, Gerard R, Hobbs, Sarah C, Maubach, Karen A, Reeve, Austin J, Seabrook, Guy R, Wafford, Keith, MacLeod, Angus M
Published in Journal of medicinal chemistry (14.03.2002)
Published in Journal of medicinal chemistry (14.03.2002)
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Chiral Base-Mediated Asymmetric Synthesis of Tricarbonyl(.eta.6-arene)chromium Complexes
Price, David A, Simpkins, Nigel S, MacLeod, Angus M, Watt, Alan P
Published in Journal of organic chemistry (01.04.1994)
Published in Journal of organic chemistry (01.04.1994)
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Optimisation of rear reflectance in ultra-thin CIGS solar cells towards >20% efficiency
Poncelet, Olivier, Kotipalli, Ratan, Vermang, Bart, Macleod, Angus, Francis, Laurent A., Flandre, Denis
Published in Solar energy (01.04.2017)
Published in Solar energy (01.04.2017)
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3,4-Dihydronaphthalen-1(2H)-ones: novel ligands for the benzodiazepine site of α5-containing GABAA receptors
SZEKERES, Helen J, ATACK, John R, CHAMBERS, Mark S, COOK, Susan M, MACAULAY, Alison J, PILLAI, Gopalan V, MACLEOD, Angus M
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
Published in Bioorganic & medicinal chemistry letters (07.06.2004)
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CO-MORBIDITY BURDEN IN PARKINSON'S DISEASE AND MATCHED CONTROLS
Goddard, Hannah, Macleod, Angus, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2015)
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Journal Article
PROGRESSION OF DISABILITY IN PD: A SYSTEMATIC REVIEW
Macleod, Angus, Grieve, Kerr, Counsell, Carl
Published in Journal of neurology, neurosurgery and psychiatry (01.10.2014)
Published in Journal of neurology, neurosurgery and psychiatry (01.10.2014)
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Journal Article
Tryptophan-Derived NK1 Antagonists: Conformationally Constrained Heterocyclic Bioisosteres of the Ester Linkage
Lewis, Richard T, Macleod, Angus M, Merchant, Kevin J, Kelleher, Fintan, Sanderson, Ian, Herbert, Richard H, Cascieri, Margaret A, Sadowski, Sharon, Ball, Richard G, Hoogsteen, Karst
Published in Journal of medicinal chemistry (01.03.1995)
Published in Journal of medicinal chemistry (01.03.1995)
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Journal Article
Novel quinuclidine-based ligands for the muscarinic cholinergic receptor
Saunders, John, Cassidy, Mark, Freedman, Stephen B, Harley, Elizabeth A, Iversen, Leslie L, Kneen, Clare, MacLeod, Angus M, Merchant, Kevin J, Snow, Roger J, Baker, Raymond
Published in Journal of medicinal chemistry (01.04.1990)
Published in Journal of medicinal chemistry (01.04.1990)
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