Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10
Wang, Xiang, Negrou, Elvira, Maloney, Michael T., Bondar, Vitaliy V., Andrews, Shan V., Montalban, Manuel, Llapashtica, Ceyda, Maciuca, Romeo, Nguyen, Hoang, Solanoy, Hilda, Arguello, Annie, Przybyla, Laralynne, Moerke, Nathan J., Huntwork-Rodriguez, Sarah, Henry, Anastasia G.
Published in Scientific reports (18.06.2021)
Published in Scientific reports (18.06.2021)
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LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease
Jennings, Danna, Huntwork‐Rodriguez, Sarah, Vissers, Maurits F.J.M., Daryani, Vinay M., Diaz, Dolores, Goo, Marisa S., Chen, John J., Maciuca, Romeo, Fraser, Kyle, Mabrouk, Omar S., Wetering de Rooij, Jeroen, Heuberger, Jules A.A.C., Groeneveld, Geert Jan, Borin, Marie T., Cruz‐Herranz, Andrés, Graham, Danielle, Scearce‐Levie, Kimberly, De Vicente, Javier, Henry, Anastasia G., Chin, Peter, Ho, Carole, Troyer, Matthew D.
Published in Movement disorders (01.03.2023)
Published in Movement disorders (01.03.2023)
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A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma
Harris, Jeffrey M, Maciuca, Romeo, Bradley, Mary S, Cabanski, Christopher R, Scheerens, Heleen, Lim, Jeremy, Cai, Fang, Kishnani, Mona, Liao, X Charlene, Samineni, Divya, Zhu, Rui, Cochran, Colette, Soong, Weily, Diaz, Joseph D, Perin, Patrick, Tsukayama, Miguel, Dimov, Dimo, Agache, Ioana, Kelsen, Steven G
Published in Respiratory research (18.03.2016)
Published in Respiratory research (18.03.2016)
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Lupus Nephritis: Induction Therapy in Severe Lupus Nephritis—Should MMF Be Considered the Drug of Choice?
Rovin, Brad H, Parikh, Samir V, Hebert, Lee A, Chan, Tak Mao, Mok, Chi Chiu, Ginzler, Ellen M, Hooi, Lai Seong, Brunetta, Paul, Maciuca, Romeo, Solomons, Neil
Published in Clinical journal of the American Society of Nephrology (01.01.2013)
Published in Clinical journal of the American Society of Nephrology (01.01.2013)
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Journal Article
Peripheral blood gene expression predicts clinical benefit from anti–IL-13 in asthma
Choy, David F., BS, Jia, Guiquan, MD, Abbas, Alexander R., PhD, Morshead, Katrina B., PhD, Lewin-Koh, Nicholas, PhD, Dua, Rajiv, PhD, Rivera, Pauline, MS, Moonsamy, Priscilla, BS, Fontecha, Marcel, BS, Balasubramanyam, Aarthi, MS, Santini, Chris, BS, Bassett, Ekaterina, PhD, Ray, Jill M., PhD, Cabanski, Christopher R., PhD, Bradley, Mary S., PhD, Maciuca, Romeo, PhD, Mosesova, Sofia, PhD, Scheerens, Heleen, PhD, Arron, Joseph R., MD, PhD
Published in Journal of allergy and clinical immunology (01.10.2016)
Published in Journal of allergy and clinical immunology (01.10.2016)
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Efficacy and Safety of Lebrikizumab in Severe Uncontrolled Asthma: Results from the Lute and Verse Phase II Randomized, Double-Blind, Placebo-Controlled Trials
Hanania, Nicola A., MD, Noonan, Michael J., MD, Corren, Jonathan, MD, Korenblat, Phillip, MD, FAAAAI, Zheng, Yanan, PhD, Putnam, Wendy, PhD, Murray, Elaine, MD, Abelardo, Connie, MD, Scheerens, Heleen, PhD, Maciuca, Romeo, PhD, Gray, Sarah, PhD, Doyle, Ramona, MD, McClintock, Dana, MD, Matthews, John G., MBBS, MRSCP, PhD, Yen, Karl, MD, MMSc, FAAP
Published in Journal of allergy and clinical immunology (01.02.2014)
Published in Journal of allergy and clinical immunology (01.02.2014)
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Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies
Hanania, Nicola A, Noonan, Michael, Corren, Jonathan, Korenblat, Phillip, Zheng, Yanan, Fischer, Saloumeh K, Cheu, Melissa, Putnam, Wendy S, Murray, Elaine, Scheerens, Heleen, Holweg, Cecile TJ, Maciuca, Romeo, Gray, Sarah, Doyle, Ramona, McClintock, Dana, Olsson, Julie, Matthews, John G, Yen, Karl
Published in Thorax (01.08.2015)
Published in Thorax (01.08.2015)
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A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)
Kalunian, Kenneth C, Merrill, Joan T, Maciuca, Romeo, McBride, Jacqueline M, Townsend, Michael J, Wei, Xiaohui, Davis, John C, Kennedy, William P
Published in Annals of the rheumatic diseases (01.01.2016)
Published in Annals of the rheumatic diseases (01.01.2016)
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Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study
Rovin, Brad H., Furie, Richard, Latinis, Kevin, Looney, R. John, Fervenza, Fernando C., Sanchez-Guerrero, Jorge, Maciuca, Romeo, Zhang, David, Garg, Jay P., Brunetta, Paul, Appel, Gerald
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2012)
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Efficacy and Safety of Ocrelizumab in Active Proliferative Lupus Nephritis: Results From a Randomized, Double‐Blind, Phase III Study
Mysler, Eduardo F., Spindler, Alberto J., Guzman, Renato, Bijl, Marc, Jayne, David, Furie, Richard A., Houssiau, Frédéric A., Drappa, Jorn, Close, David, Maciuca, Romeo, Rao, Kajal, Shahdad, Saba, Brunetta, Paul
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2013)
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Randomized Phase I Healthy Volunteer Study of UTTR1147A (IL-22Fc): A Potential Therapy for Epithelial Injury
Rothenberg, Michael E, Wang, Yehong, Lekkerkerker, Annemarie, Danilenko, Dimitry M, Maciuca, Romeo, Erickson, Rich, Herman, Ann, Stefanich, Eric, Lu, Timothy T
Published in Clinical pharmacology and therapeutics (01.01.2019)
Published in Clinical pharmacology and therapeutics (01.01.2019)
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Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study
McBride, Jacqueline M., Jiang, Jenny, Abbas, Alexander R., Morimoto, Alyssa, Li, Jing, Maciuca, Romeo, Townsend, Michael, Wallace, Daniel J., Kennedy, William P., Drappa, Jorn
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2012)
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Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease
Jennings, Danna, Huntwork-Rodriguez, Sarah, Henry, Anastasia G, Sasaki, Jennifer C, Meisner, René, Diaz, Dolores, Solanoy, Hilda, Wang, Xiang, Negrou, Elvira, Bondar, Vitaliy V, Ghosh, Rajarshi, Maloney, Michael T, Propson, Nicholas E, Zhu, Yuda, Maciuca, Romeo D, Harris, Laura, Kay, Angela, LeWitt, Peter, King, T Alex, Kern, Drew, Ellenbogen, Aaron, Goodman, Ira, Siderowf, Andrew, Aldred, Jason, Omidvar, Omid, Masoud, Shababa T, Davis, Sonnet S, Arguello, Annie, Estrada, Anthony A, de Vicente, Javier, Sweeney, Zachary K, Astarita, Giuseppe, Borin, Marie T, Wong, Bradley K, Wong, Harvey, Nguyen, Hoang, Scearce-Levie, Kimberly, Ho, Carole, Troyer, Matthew D
Published in Science translational medicine (08.06.2022)
Published in Science translational medicine (08.06.2022)
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Journal Article
Association of caffeine and related analytes with resistance to Parkinson disease among LRRK2 mutation carriers: A metabolomic study
Crotty, Grace F, Maciuca, Romeo, Macklin, Eric A, Wang, Junhua, Montalban, Manuel, Davis, Sonnet S, Alkabsh, Jamal I, Bakshi, Rachit, Chen, Xiqun, Ascherio, Alberto, Astarita, Giuseppe, Huntwork-Rodriguez, Sarah, Schwarzschild, Michael A
Published in Neurology (15.12.2020)
Published in Neurology (15.12.2020)
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Su1938 - Colonic Treg Levels are Reduced in Patients with UC Achieving Clinical Remission, but are not Differentially Affected by Etrolizumab Dose
Fuh, Franklin, Tew, Wei, Keir, Mary, Looney, Caroline, Maciuca, Romeo, McBride, Jacqueline, Ramirez-Montagut, Teresa
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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Su1935 - Etrolizumab Demonstrated no Difference Among Doses in Symptomatic and Endoscopic-Based Evaluation of Remission in Anti-TNF-α Naïve Patients in a Post hoc Analysis of the Phase 2 Ulcerative Colitis Trial (Eucalyptus)
Sandborn, William J., Schreiber, Stefan, Tang, Meina, Tatro, Amanda, Oh, Young S., Maciuca, Romeo
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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Journal Article
Colonic Treg Levels are Reduced in Patients with UC Achieving Clinical Remission, but are not Differentially Affected by Etrolizumab Dose
Fuh, Franklin, Tew, Wei, Keir, Mary, Looney, Caroline, Maciuca, Romeo, McBride, Jacqueline, Ramirez-Montagut, Teresa
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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Development of a Disease Progression Model for Leucine-Rich Repeat Kinase 2 in Parkinson's Disease to Inform Clinical Trial Designs
Ahamadi, Malidi, Conrado, Daniela J, Macha, Sreeraj, Sinha, Vikram, Stone, Julie, Burton, Jackson, Nicholas, Timothy, Gallagher, Jill, Dexter, David, Bani, Massimo, Boroojerdi, Babak, Smit, Hans, Weidemann, Jonas, Chen, Chao, Yang, Minhua, Maciuca, Romeo, Lawson, Rachael, Burn, David, Marek, Kenneth, Venuto, Charles, Stafford, Bob, Akalu, Mussie, Stephenson, Diane, Romero, Klaus
Published in Clinical pharmacology and therapeutics (01.03.2020)
Published in Clinical pharmacology and therapeutics (01.03.2020)
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Su1692 ANALYSIS OF VARIOUS CENTRAL ENDOSCOPY READING METHODOLOGIES IN THE BERGAMOT EXPLORATORY INDUCTION COHORT EVALUATING ETROLIZUMAB IN CROHN’S DISEASE
Reinisch, Walter, Mishkin, Daniel, Oh, Young S., Schreiber, Stefan, Maciuca, Romeo, Jacob, Rhian, Hassanali, Azra, Arulmani, Udayasankar, Daperno, Marco
Published in Gastrointestinal endoscopy (01.06.2018)
Published in Gastrointestinal endoscopy (01.06.2018)
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Etrolizumab Treatment Improves Histologic Activity as Assessed by Both the Robarts Histopathology and Nancy Histological Indices: P-105
Laurent, Peyrin-Biroulet, Brian, Feagan, De Hertogh, Gert, Rubin, David T., Romeo, Maciuca, Jacqueline, McBride, Udayasankar, Arulmani, Alexis, Scherl
Published in The American journal of gastroenterology (01.02.2018)
Published in The American journal of gastroenterology (01.02.2018)
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