STUDIES ON ORALLY ACTIVE CEPHALOSPORINS: I. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF NEW 3-SUBSTITUTED CARBAMOYLOXYMETHYL CEPHALOSPORINS
NEGI, SHIGETO, YAMANAKA, MOTOSUKE, SUGIYAMA, ISAO, KOMATSU, YUKI, SASHO, MANABU, TSURUOKA, AKIHIKO, KAMADA, ATSUSHI, TSUKADA, ITARU, HIRUMA, RYOICHI, KATSU, KANEMASA, MACHIDA, YOSHIMASA
Published in Journal of antibiotics (1994)
Published in Journal of antibiotics (1994)
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A Practical Synthetic Method for 3-(N,N-Disubstituted Carbamoyloxy)methyl Cephems without Generating the .DELTA.2-Isomers
NEGI, Shigeto, YAMANAKA, Motosuke, KOMATSU, Yuki, TSURUOKA, Akihiko, KAMADA, Atsushi, TSUKADA, Itaru, MACHIDA, Yoshimasa
Published in Chemical & pharmaceutical bulletin (1995)
Published in Chemical & pharmaceutical bulletin (1995)
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Studies on orally active cephalosporins. II. Synthesis and structure-activity relations of new ((E) or (Z) 3-substituted carbamoyloxy)-1-propenyl cephalosporins
NEGI, SHIGETO, SASHO, MANABU, YAMANAKA, MOTOSUKE, SUGIYAMA, ISAO, KOMATSU, YUKI, TSURUOKA, AKIHIKO, KAMADA, ATSUSHI, TSUKADA, ITARU, HIRUMA, RYOICHI, KATSU, KANEMASA, MACHIDA, YOSHIMASA
Published in Journal of antibiotics (1994)
Published in Journal of antibiotics (1994)
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Hapten Synthesis for (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimethyl-2,3,4,5-tetrahydro-8H-phyido(4',3':4,5)thieno(3,2-f)triazolo(4,3-a)(1,4)diazepine (E6123)
MIYAZAWA, Shuhei, OKANO, Kazuo, KAWAHARA, Tetsuya, MACHIDA, Yoshimasa, YAMATSU, Isao
Published in Chemical & pharmaceutical bulletin (1992)
Published in Chemical & pharmaceutical bulletin (1992)
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Structure-activity studies on triazolothienodiazepine derivatives as platelet-activating factor antagonists
Miyazawa, S, Okano, K, Shimomura, N, Clark, R S, Kawahara, T, Asano, O, Yoshimura, H, Miyamoto, M, Sakuma, Y, Muramoto, K
Published in Chemical & pharmaceutical bulletin (1991)
Published in Chemical & pharmaceutical bulletin (1991)
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A Practical Synthesis of Optically Active Platelet-Activating Factor Antagonist, (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8,11-dimetyl-2,3,4,5-tetrahydro-8H-pyrido(4',3':4,5)thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine(E6123), and Its Absolute Configuration
MIYAZAWA, Shuhei, OKANO, Kazuo, SHIMOMURA, Naoyuki, KAWAHARA, Tetsuya, ASANO, Osamu, YOSHIMURA, Hiroyuki, KAWAI, Takatoshi, SOUDA, Shigeru, YOSHIDA, Yutaka, SATO, Tadashi, MACHIDA, Yoshimasa, YAMATSU, Isao
Published in Chemical & pharmaceutical bulletin (1992)
Published in Chemical & pharmaceutical bulletin (1992)
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Complex Formation between Mycobacterial Polysaccharides and Fatty Acyl-CoA Derivatives
Machida, Yoshimasa, Bloch, Konrad
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1973)
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1973)
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Effects of Cyclodextrins on Fatty Acid Synthesis
Machida, Yoshimasa, Bergeron, Ray, Flick, Parke, Bloch, Konrad
Published in The Journal of biological chemistry (10.09.1973)
Published in The Journal of biological chemistry (10.09.1973)
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PROCESS FOR PREPARING CEPHEM DERIVATIVES
SAITO, ISAO, YAMAUCHI, HIROSHI, MACHIDA, YOSHIMASA, NOMOTO, SEICHIRO, KAMIYA, TAKASHI, SUKIYAMA, ISAO, NEKI, SHIGETO
Year of Publication 19.05.1993
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Year of Publication 19.05.1993
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CEPHALOSPORIN DERIVATIVES
NAITO, TOSHIHIKO, MACHIDA, YOSHIMASA, YAMAUCHI, HIROSHI, KAMIYA, TAKASHI, KOMATSU, YUUKI, NOMOTO, SEIICHIRO, NEGI, SHIGETO, SUGIYAMA, ISAO
Year of Publication 02.07.1987
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Year of Publication 02.07.1987
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PROCESS FOR PREPARING 7-METHOXY-CEPHALOSPORIN DERIVATIVES
SAITO, ISAO, IKUTA, JIRONORI, MACHIDA, YOSHIMASA, NEGI, SHIGTO, KITOH, KYOSUKE, NOMOTO, SEIICHIRO
Year of Publication 24.11.1984
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Year of Publication 24.11.1984
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BIPHENYL DERIVATIVES
AKASAKA, KOZO, UENO, KOHSHI, KOMATSU, YUKI, KAJIWARA AKIHARU, SHIMIZU, TOSHIKAZU, MACHIDA, YOSHIMASA, YONAGA, MASAHIRO, KOMATSU, MAKOTO, UENO, MASATAKA, NAGAOKA, ATSUSHI, NAGATO, SATOSHI, HIGURASHI, KUNIZO, MINAMI, NORIO, YAMANISHI, YOSHIHARU, SHIMOMURA, NAOYUKI, KITAZAWA, NORITAKA
Year of Publication 15.06.1999
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Year of Publication 15.06.1999
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3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICA INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE
KATSU, KANEMASA, NAITO, TOSHIHIKO, MACHIDA, YOSHIMASA, KITO, KYOSUKE, YAMAUCHI, HIROSHI, KOMATU, YUUKI, KAI, YASUNOBU, KAMIYA, TAKASHI, NOMOTO, SEICHIRO, NAKAMURA, TAKAHARU, NEGI, SHIGETO, SUGIYAMA, ISAO
Year of Publication 09.10.1995
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Year of Publication 09.10.1995
Patent
NAPHTHALENE DERIVATIVE
YAMATSU, ISAO, KAYAYAMA, KOUICHI, MACHIDA, YOSHIMASA, SAKURAI, HIDEKI, CHIBA, KENICHI, NOMOTO, SEIICHRO, OHHARA, HIDETO, TAGAKA, MASAYUKI, OKAMOTO, YASUSHI, GOTO, MASAKI, SOUDA, SHIGERU, ONO, HIDEKI, OKITA, MAKOTO, TAGAMI, KATSUYA, SUZUKI, TAKESHI
Year of Publication 18.04.1992
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Year of Publication 18.04.1992
Patent
A Practical Synthetic Method for 3-(N, N-Disubstituted Carbamoyloxy)-methyl Cephems without Generating the [delta]2-Isomers
NEGI, Shigeto, YAMANAKA, Motosuke, KOMATSU, Yuki, TSURUOKA, Akihiko, KAMADA, Atsushi, TSUKADA, Itaru, MACHIDA, Yoshimasa
Published in Chemical & pharmaceutical bulletin (01.06.1995)
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Published in Chemical & pharmaceutical bulletin (01.06.1995)
Journal Article
Hapten Synthesis for (+)-6-(2-Chlorophenyl)-3-cyclopropanecarbonyl-8, 11-dimethyl-2, 3, 4, 5-tetrahydro-8H-pyrido[4', 3' : 4, 5]thieno[3, 2-f]triazolo[4, 3-a][1, 4]diazepine(E6123)
MIYAZAWA, Shuhei, OKANO, Kazuo, KAWAHARA, Tetsuya, MACHIDA, Yoshimasa, YAMATSU, Isao
Published in Chemical and Pharmaceutical Bulletin (25.03.1992)
Published in Chemical and Pharmaceutical Bulletin (25.03.1992)
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