Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain
Machen, Alexandra J, Akkaladevi, Narahari, Trecazzi, Caleb, O'Neil, Pierce T, Mukherjee, Srayanta, Qi, Yifei, Dillard, Rebecca, Im, Wonpil, Gogol, Edward P, White, Tommi A, Fisher, Mark T
Published in Toxins (22.09.2017)
Published in Toxins (22.09.2017)
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The Chaperonin GroEL: A Versatile Tool for Applied Biotechnology Platforms
O'Neil, Pierce T, Machen, Alexandra J, Deatherage, Benjamin C, Trecazzi, Caleb, Tischer, Alexander, Machha, Venkata R, Auton, Matthew T, Baldwin, Michael R, White, Tommi A, Fisher, Mark T
Published in Frontiers in molecular biosciences (15.05.2018)
Published in Frontiers in molecular biosciences (15.05.2018)
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Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV)
Dampalla, Chamandi S., Miller, Matthew J., Kim, Yunjeong, Zabiegala, Alexandria, Nguyen, Harry Nhat, Madden, Trent K., Thurman, Hayden A., Machen, Alexandra J., Cooper, Anne, Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Published in European journal of medicinal chemistry (05.06.2023)
Published in European journal of medicinal chemistry (05.06.2023)
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Crystal structures of NAD(P)H nitroreductases from Klebsiella pneumoniae
Kancherla, Abhishek D, Liu, Lijun, Tillery, Logan, Shek, Roger, Craig, Justin K, Machen, Alexandra J, Seibold, Steve, Battaile, Kevin P, Fradi, Selma, Barrett, Lynn K, Subramanian, Sandhya, Myler, Peter, Van Voorhis, Wesley C, Lovell, Scott
Published in Acta crystallographica. Section F, Structural biology communications (01.08.2024)
Published in Acta crystallographica. Section F, Structural biology communications (01.08.2024)
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Prolongation of islet allograft survival following ex vivo transduction with adenovirus encoding a soluble type 1 TNF receptor-Ig fusion decoy
MACHEN, J, BERTERA, S, CHANG, Y, BOTTINO, R, BALAMURUGAN, A. N, ROBBINS, P. D, TRUCCO, M, GIANNOUKAKIS, N
Published in Gene therapy (01.10.2004)
Published in Gene therapy (01.10.2004)
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Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies
Dampalla, Chamandi S., Nguyen, Harry Nhat, Rathnayake, Athri D., Kim, Yunjeong, Perera, Krishani Dinali, Madden, Trent K., Thurman, Hayden A., Machen, Alexandra J., Kashipathy, Maithri M., Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Published in ACS pharmacology & translational science (13.01.2023)
Published in ACS pharmacology & translational science (13.01.2023)
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Constructing Kinetically Controlled Denaturation Isotherms of Folded Proteins Using Denaturant-Pulse Chaperonin Binding
O'Neil, Pierce T, Machen, Alexandra J, Thompson, Jackie A, Wang, Wei, Hoang, Quyen Q, Baldwin, Michael R, Khar, Karen R, Karanicolas, John, Fisher, Mark T
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Chaperonin-Based Biolayer Interferometry To Assess the Kinetic Stability of Metastable, Aggregation-Prone Proteins
Lea, Wendy A, O’Neil, Pierce T, Machen, Alexandra J, Naik, Subhashchandra, Chaudhri, Tapan, McGinn-Straub, Wesley, Tischer, Alexander, Auton, Matthew T, Burns, Joshua R, Baldwin, Michael R, Khar, Karen R, Karanicolas, John, Fisher, Mark T
Published in Biochemistry (Easton) (06.09.2016)
Published in Biochemistry (Easton) (06.09.2016)
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Analyzing Dynamic Protein Complexes Assembled On and Released From Biolayer Interferometry Biosensor Using Mass Spectrometry and Electron Microscopy
Machen, Alexandra J, O'Neil, Pierce T, Pentelute, Bradley L, Villar, Maria T, Artigues, Antonio, Fisher, Mark T
Published in Journal of visualized experiments (06.08.2018)
Published in Journal of visualized experiments (06.08.2018)
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