Evaluation of the hepatotoxicity of the novel GPR40 (FFAR1) agonist CPL207280 in the rat and monkey
Bazydlo-Guzenda, Katarzyna, Buda, Pawel, Mach, Mateusz, Pieczykolan, Jerzy, Kozlowska, Izabela, Janiszewski, Michal, Drzazga, Ewa, Dominowski, Jakub, Ziolkowski, Hubert, Wieczorek, Maciej, Gad, Shayne Cox
Published in PloS one (23.09.2021)
Published in PloS one (23.09.2021)
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Journal Article
Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II—Benzimidazole Derivatives
Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (27.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (27.07.2022)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
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Journal Article
Comparing n-pentenyl orthoesters and n-pentenyl glycosides as alternative glycosyl donors
Mach, Mateusz, Schlueter, Urs, Mathew, Felix, Fraser-Reid, Bert, Hazen, Kevin C
Published in Tetrahedron (02.09.2002)
Published in Tetrahedron (02.09.2002)
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Journal Article
Evaluation of the hepatotoxicity of the novel GPR40
Bazydlo-Guzenda, Katarzyna, Buda, Pawel, Mach, Mateusz, Pieczykolan, Jerzy, Kozlowska, Izabela, Janiszewski, Michal, Drzazga, Ewa, Dominowski, Jakub, Ziolkowski, Hubert, Wieczorek, Maciej, Gad, Shayne Cox
Published in PloS one (23.09.2021)
Published in PloS one (23.09.2021)
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Journal Article
CPL207280, a Novel G Protein–Coupled Receptor 40/Free Fatty Acid Receptor 1–Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals
Bazydlo-Guzenda, Katarzyna, Buda, Pawel, Matloka, Mikolaj, Mach, Mateusz, Stelmach, Filip, Dzida, Radoslaw, Smuga, Damian, Hucz-Kalitowska, Joanna, Teska-Kaminska, Malgorzata, Vialichka, Varvara, Dubiel, Krzysztof, Kaminska, Bozena, Wieczorek, Maciej, Pieczykolan, Jerzy
Published in Molecular pharmacology (01.10.2021)
Published in Molecular pharmacology (01.10.2021)
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Journal Article
Discovery and development of CPL207280 as new GPR40/FFA1 agonist
Mach, Mateusz, Bazydło-Guzenda, Katarzyna, Buda, Paweł, Matłoka, Mikołaj, Dzida, Radosław, Stelmach, Filip, Gałązka, Kinga, Wąsińska-Kałwa, Małgorzata, Smuga, Damian, Hołowińska, Dagmara, Dawid, Urszula, Gurba-Bryśkiewicz, Lidia, Wiśniewski, Krzysztof, Dubiel, Krzysztof, Pieczykolan, Jerzy, Wieczorek, Maciej
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
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Journal Article
Discovery of CPL207-280CA, an Effective and Safe GPR40 Agonist for the Treatment of Type 2 Diabetes
BAZYDLO, KATARZYNA, BUDA, PAWEL, MACH, MATEUSZ, DZIDA, RADOSłAW, STELMACH, FILIP, DUBIEL, KRZYSZTOF K., PIECZYKOLAN, JERZY S., WIECZOREK, MACIEJ
Published in Diabetes (New York, N.Y.) (01.07.2018)
Published in Diabetes (New York, N.Y.) (01.07.2018)
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Journal Article
Esketamine inhaled as dry powder: Pharmacokinetic, pharmacodynamic and safety assessment in a preclinical study
Matłoka, Mikołaj, Janowska, Sylwia, Gajos-Draus, Anna, Ziółkowski, Hubert, Janicka, Monika, Perko, Przemysław, Kamil, Kisło, Pankiewicz, Piotr, Moszczyński-Pętkowski, Rafał, Mach, Mateusz, Dera, Paulina, Abramski, Krzysztof, Teska-Kamińska, Małgorzata, Tratkiewicz, Ewa, Wieczorek, Maciej, Pieczykolan, Jerzy
Published in Pulmonary pharmacology & therapeutics (01.06.2022)
Published in Pulmonary pharmacology & therapeutics (01.06.2022)
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Journal Article
2333-PUB: CPL207-280, a Potent and Safe GPR40 Agonist for the treatment of Type 2 Diabetes
BAZYDLO-GUZENDA, KATARZYNA, BUDA, PAWEL, KOZLOWSKA, IZABELA, MACH, MATEUSZ, TESKA-KAMINSKA, MALGORZATA, STELMACH, FILIP, WASINSKA-KALWA, MALGORZATA, GALAZKA, KINGA, DUBIEL, KRZYSZTOF K., PIECZYKOLAN, JERZY S., WIECZOREK, MACIEJ
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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Journal Article
Design, Synthesis, and Development of Pyrazolo[1,5-Ia/I]pyrimidine Derivatives as a Novel Series of Selective PI3KIδ/I Inhibitors: Part II—Benzimidazole Derivatives
Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-Ia/I]pyrimidine Derivatives as a Novel Series of Selective PI3KIδ/I Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
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Journal Article
GPR40 작용제로서 3-페닐-4-헥신산 유도체
MACH MATEUSZ, STELMACH FILIP, DZIDA RADOSLAW, BAZYDLO KATARZYNA, MATLOKA MIKOLAJ, WIECZOREK MACIEJ, PIECZYKOLAN JERZY, DUBIEL KRZYSZTOF, SMUGA DAMIAN
Year of Publication 17.09.2020
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Year of Publication 17.09.2020
Patent
Unexpected Role of O-2 “Protecting” Groups of Glycosyl Donors in Mediating Regioselective Glycosidation
Fraser-Reid, Bert, Lopez, J. Cristobal, Radhakrishnan, K. V, Mach, Mateusz, Schlueter, Urs, Gomez, Ana M, Uriel, Clara
Published in Journal of the American Chemical Society (03.04.2002)
Published in Journal of the American Chemical Society (03.04.2002)
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Journal Article
Derivados del ácido 3-fenil-4-hexinoico como agonistas de GPR40
MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 04.06.2024
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Year of Publication 04.06.2024
Patent
3-PHENYL-4-HEXYNSYREDERIVATER SOM GPR40-AGONISTER
MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 27.05.2024
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Year of Publication 27.05.2024
Patent
3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS
MACH, Mateusz, SMUGA, Damian, STELMACH, Filip, DUBIEL, Krzysztof, DZIDA, Radoslaw, PIECZYKOLAN, Jerzy, MATLOKA, Mikolaj, BAZYDLO, Katarzyna, WIECZOREK, Maciej
Year of Publication 15.05.2024
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Year of Publication 15.05.2024
Patent