CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma
KAM FAI TSE, JEFFERS, Michael, MACDOUGALL, John R, RASTELLI, Luca, HERRMANN, John, GALLO, Michael, GAZIT-BORNSTEIN, Gadi, SENTER, Peter D, MEYER, Damon L, LICHENSTEIN, Henri S, LAROCHELLE, William J, POLLACK, Vincent A, MCCABE, Denise A, SHADISH, Melanie L, KHRAMTSOV, Nikolai V, HACKETT, Craig S, SHENOY, Suresh G, BING KUANG, BOLDOG, Ferenc L
Published in Clinical cancer research (15.02.2006)
Published in Clinical cancer research (15.02.2006)
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Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB
POLLACK, Vincent A, ALVAREZ, Enrique, HAHNE, William F, SENTER, Peter D, JEFFERS, Michael E, LICHENSTEIN, Henri S, LAROCHELLE, William J, KAM FAI TSE, TORGOV, Michael Y, SAM XIE, SHENOY, Suresh G, MACDOUGALL, John R, ARROL, Sharon, HAIHONG ZHONG, GERWIEN, Robert W
Published in Cancer chemotherapy and pharmacology (01.08.2007)
Published in Cancer chemotherapy and pharmacology (01.08.2007)
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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model
McCann, Christopher K, Growdon, Whitfield B, Kulkarni-Datar, Kashmira, Curley, Michael D, Friel, Anne M, Proctor, Jennifer L, Sheikh, Hana, Deyneko, Igor, Ferguson, Jeanne A, Vathipadiekal, Vinod, Birrer, Michael J, Borger, Darrell R, Mohapatra, Gayatry, Zukerberg, Lawrence R, Foster, Rosemary, Macdougall, John R, Rueda, Bo R
Published in PloS one (29.11.2011)
Published in PloS one (29.11.2011)
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An Infrared Dye-Conjugated Virus-like Particle for the Treatment of Primary Uveal Melanoma
Kines, Rhonda C, Varsavsky, Isabella, Choudhary, Sanghamitra, Bhattacharya, Debaditya, Spring, Sean, McLaughlin, Roger, Kang, Shin J, Grossniklaus, Hans E, Vavvas, Demetrios, Monks, Stephen, MacDougall, John R, de Los Pinos, Elisabet, Schiller, John T
Published in Molecular cancer therapeutics (01.02.2018)
Published in Molecular cancer therapeutics (01.02.2018)
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PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models
Winkler, David G., Faia, Kerrie L., DiNitto, Jonathan P., Ali, Janid A., White, Kerry F., Brophy, Erin E., Pink, Melissa M., Proctor, Jennifer L., Lussier, Jennifer, Martin, Christian M., Hoyt, Jennifer G., Tillotson, Bonnie, Murphy, Erin L., Lim, Alice R., Thomas, Brian D., MacDougall, John R., Ren, Pingda, Liu, Yi, Li, Lian-Sheng, Jessen, Katti A., Fritz, Christian C., Dunbar, Joi L., Porter, James R., Rommel, Christian, Palombella, Vito J., Changelian, Paul S., Kutok, Jeffery L.
Published in Chemistry & biology (21.11.2013)
Published in Chemistry & biology (21.11.2013)
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Recombinant Human FIZZ3/Resistin Stimulates Lipolysis in Cultured Human Adipocytes, Mouse Adipose Explants, and Normal Mice
Ort, Tatiana, Arjona, Anibal A, MacDougall, John R, Nelson, Pam J, Rothenberg, Mark E, Wu, Frank, Eisen, Andrew, Halvorsen, Yuan-Di C
Published in Endocrinology (Philadelphia) (01.05.2005)
Published in Endocrinology (Philadelphia) (01.05.2005)
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Abstract 4946: TOS-358, a first-in-class covalent PI3Kα inhibitor, demonstrates superior efficacy and does not induce significant hyperglycemia at efficacious doses in multiple animal models
MacDougall, John R., Bradley, John, Mak, Raymond, Dhawan, Neil, Chen, Wei
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 4945: Inhibition of wild-type PI3Kα signaling is required for durable efficacy in PI3Kα mutant cancer cells due to robust re-activation of wild-type PI3Kα signaling
MacDougall, John R., Zhong, Mengqi, Merritt, Hanne, Cid, Joselyn S. Del, Bradley, John, Mak, Raymond, Dhawan, Neil, Chen, Wei
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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The Melanoma Vascular Mimicry Phenotype Defined in Gene Expression and Microsome Sequencing Analysis
JINGFANG JU, LUCA RASTELLI, URIEL M. MALYANKER, JAN F. SIMONS, CHUNLI HUANG, JOHN HERRMANN, JOHN R. MACDOUGALL, BRUCE E. TAILLON
Published in Cancer genomics & proteomics (01.09.2004)
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Published in Cancer genomics & proteomics (01.09.2004)
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Abstract 2249: Development and validation of a pharmacodynamic (PD) assay for TOS-358, the first covalent inhibitor of PI3Kα in clinical development
MacDougall, John R., Mak, Raymond, Bradley, John, Simpson, Allison, May, Claire, Wei, Lan, Ouellette, Kendra, Olbrot, Marty, Blair, Jimmy, Dhawan, Neil, Chen, Wei
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 1770: Viral-based nanoparticles: a new therapeutic approach for anticancer therapy
Kines, Rhonda, Bhattacharya, Debaditya, MacDougall, John R., Milenic, Diane, Brechbiel, Martin W., Pinos, Elisabet de los, Schiller, John T.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Demonstration of a splenic cytotoxic effector cell in mice of genotype SCID/SCID.BG/BG
MacDougall, John R., Croy, B.Anne, Chapeau, Christine, Clark, David A.
Published in Cellular immunology (01.10.1990)
Published in Cellular immunology (01.10.1990)
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Abstract 3285: Hedgehog pathway inhibition delays regrowth of ovarian cancer following paclitaxel and carboplatinum only if initiated immediately after completion of chemotherapy
Kulkarni-Datar, Kashmira S., Growdon, Whitfield B., Ferguson, Jeanne A., MacDougall, John R., Foster, Rosemary, Rueda, Bo R.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 5045: The Hh inhibitor IPI-926 inhibits relapse of a non-small cell lung cancer xenograft model following treatment with an EGF-R targeted tyrosine kinase inhibitor
Mandley, Everton, White, Kerry, Faia, Kerrie, Travaglione, Veronica, Read, Margaret, McGovern, Karen, MacDougall, John R.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption
Haro, H, Crawford, H C, Fingleton, B, MacDougall, J R, Shinomiya, K, Spengler, D M, Matrisian, L M
Published in The Journal of clinical investigation (01.01.2000)
Published in The Journal of clinical investigation (01.01.2000)
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Establishment and Characterization of First Trimester Human Trophoblast Cells with Extended Lifespan
Graham, Charles H., Hawley, Teresa S., Hawley, Robert C., MacDougall, John R., Kerbel, Robert S., Khoo, Nelson, Lala, Peeyush K.
Published in Experimental cell research (01.06.1993)
Published in Experimental cell research (01.06.1993)
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