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Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib
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Abstract 4956: Functional characterization of the ivosidenib (AG-120) and azacitidine combination in a mutant IDH1 AML cell model
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CC-486 Mechanism Imparted By Extended Exposure of Azacitidine Upregulates Myeloid Differentiation Markers and Induces Cell Death in AML Cells
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Effect of Luspatercept on Biomarkers of Erythropoiesis in Patients (Pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the Medalist Trial
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Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia
Acar, Melih, Jupelli, Madhulika, Abbiati, Roberto A., Ramanathan, Harish N., Santini, Cristina C., Ratushny, Alexander, Dunshee, Diana R., Lopes de Menezes, Daniel, MacBeth, Kyle, Suragani, Rajasekhar N.V.S., Loos, Remco, Schwickart, Martin
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Combination of Enasidenib and Venetoclax Shows Superior Anti-Leukemic Activity Against IDH2 Mutated AML in Patient-Derived Xenograft Models
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Year of Publication 01.08.2022
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Luspatercept Significantly Reduces Red Blood Cell (RBC) Transfusion Burden, Regardless of Gene Mutation Frequency, Spectrum, and Prognostic Significance, Among Patients (Pts) with LR-MDS Enrolled in the MEDALIST Trial
Platzbecker, Uwe, Dunshee, Diana, Komrokji, Rami S., Mufti, Ghulam J., Garcia-Manero, Guillermo, Buckstein, Rena, Santini, Valeria, Díez-Campelo, María, Sekeres, Mikkael A., See, Wendy L., Tsai, Kevin, Risueño, Alberto, Ma, Jianglin, Schwickart, Martin, Rampersad, Anita, Zhang, Jennie, Laadem, Abderrahmane, Menezes, Daniel, MacBeth, Kyle, Linde, Peter G., Reynolds, Joseph G., List, Alan F., Fenaux, Pierre
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Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 (IDH2) Mutations: Interim Phase II Results from an Ongoing, Randomized Study
DiNardo, Courtney D., Schuh, Andre C., Stein, Eytan M., Fernandez, Pau Montesinos, Wei, Andrew, De Botton, Stephane, Zeidan, Amer M., Fathi, Amir T., Quek, Lynn, Kantarjian, Hagop M., Frattini, Mark G., Lersch, Frederik, Gong, Jing, Franovic, Aleksandra, MacBeth, Kyle, Vyas, Paresh, Döhner, Hartmut
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The class‐I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6‐independent mechanism
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Impact of Somatic Gene Mutations on Response to Lenalidomide (LEN) in IPSS Lower-Risk Myelodysplastic Syndromes (MDS) Patients (Pts) without Del(5q) and Ineligible for or Refractory to Erythropoiesis-Stimulating Agents (ESAs)
Santini, Valeria, Fenaux, Pierre, Giagounidis, Aristoteles, Platzbecker, Uwe, List, Alan F, Zhong, Jianhua, Wu, Chengqing, Mavrommatis, Konstantinos, Beach, C.L., Hoenekopp, Albert, MacBeth, Kyle J.
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Impact of Gene Mutations on Overall Survival in Older Patients with Acute Myeloid Leukemia (AML) Treated with Azacitidine (AZA) or Conventional Care Regimens (CCR)
Tang, Lin, Dolnik, Anna, MacBeth, Kyle J., Dombret, Hervé, Seymour, John F., Minden, Mark D., Stone, Richard M., Beach, C.L., Döhner, Hartmut, Bullinger, Lars
Published in Blood (02.12.2016)
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