A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis
OSTENDORF, Tammo, VAN ROEYEN, Claudia R. C, KEYT, Bruce A, LICHENSTEIN, Henri S, LAROCHELLE, William J, FLOEGE, Jürgen, PETERSON, Jeffrey D, KUNTER, Uta, EITNER, Frank, HAMAD, Avin J, CHAN, Gerlinde, JIA, Xiao-Chi, MACALUSO, Jennifer, GAZIT-BORNSTEIN, Gadi
Published in Journal of the American Society of Nephrology (01.09.2003)
Published in Journal of the American Society of Nephrology (01.09.2003)
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Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase
Currie, Kevin S, Kropf, Jeffrey E, Lee, Tony, Blomgren, Peter, Xu, Jianjun, Zhao, Zhongdong, Gallion, Steve, Whitney, J. Andrew, Maclin, Deborah, Lansdon, Eric B, Maciejewski, Patricia, Rossi, Ann Marie, Rong, Hong, Macaluso, Jennifer, Barbosa, James, Di Paolo, Julie A, Mitchell, Scott A
Published in Journal of medicinal chemistry (08.05.2014)
Published in Journal of medicinal chemistry (08.05.2014)
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Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models
Gough, Sheryl M, Flanagan, John J, Teh, Jessica, Andreoli, Monica, Rousseau, Emma, Pannone, Melissa, Bookbinder, Mark, Willard, Ryan, Davenport, Kim, Bortolon, Elizabeth, Cadelina, Gregory, Gordon, Debbie, Pizzano, Jennifer, Macaluso, Jennifer, Soto, Leofal, Corradi, John, Digianantonio, Katherine, Drulyte, Ieva, Morgan, Alicia, Quinn, Connor, Békés, Miklós, Ferraro, Caterina, Chen, Xin, Wang, Gan, Dong, Hanqing, Wang, Jing, Langley, David R, Houston, John, Gedrich, Richard, Taylor, Ian C
Published in Clinical cancer research (15.08.2024)
Published in Clinical cancer research (15.08.2024)
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Abstract 43: Discovery of ARV-110, a first in class androgen receptor degrading PROTAC for the treatment of men with metastatic castration resistant prostate cancer
Snyder, Lawrence B., Neklesa, Taavi K., Chen, Xin, Dong, Hanqing, Ferraro, Caterina, Gordon, Deborah A., Macaluso, Jennifer, Pizzano, Jennifer, Wang, Jing, Willard, Ryan R., Vitale, Nicholas, Peck, Ron, Moore, Marcia Dougan, Crews, Craig M., Houston, John, Crew, Andrew P., Taylor, Ian
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
Raina, Kanak, Forbes, Chris D., Stronk, Rebecca, Rappi, Jonathan P., Eastman, Kyle J., Zaware, Nilesh, Yu, Xinheng, Li, Hao, Bhardwaj, Amit, Gerritz, Samuel W., Forgione, Mia, Hundt, Abigail, King, Madeline P., Posner, Zoe M., Correia, Allison D., McGovern, Andrew, Puleo, David E., Chenard, Rebekka, Mousseau, James J., Vergara, J. Ignacio, Garvin, Ethan, Macaluso, Jennifer, Martin, Michael, Bassoli, Kyle, Jones, Kelli, Garcia, Marco, Howard, Katia, Yaggi, Madeleine, Smith, Levi M., Chen, Jinshan M., Mayfield, Andrew B., De Leon, Cesar A., Hines, John, Kayser-Bricker, Katherine J., Crews, Craig M.
Published in Cell chemical biology (15.08.2024)
Published in Cell chemical biology (15.08.2024)
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ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer
Neklesa, Taavi, Snyder, Lawrence B, Willard, Ryan R, Vitale, Nicholas, Pizzano, Jennifer, Gordon, Deborah A, Bookbinder, Mark, Macaluso, Jennifer, Dong, Hanqing, Ferraro, Caterina, Wang, Gan, Wang, Jing, Crews, Craig M, Houston, John, Crew, Andrew P, Taylor, Ian
Published in Journal of clinical oncology (01.03.2019)
Published in Journal of clinical oncology (01.03.2019)
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Abstract 5236: ARV-110: An androgen receptor PROTAC degrader for prostate cancer
Neklesa, Taavi, Snyder, Lawrence B., Willard, Ryan R., Vitale, Nicholas, Raina, Kanak, Pizzano, Jennifer, Gordon, Deborah, Bookbinder, Mark, Macaluso, Jennifer, Dong, Hanqing, Liu, Zheng, Ferraro, Caterina, Wang, Gan, Wang, Jing, Crews, Craig M., Houston, John, Crew, Andrew P., Taylor, Ian
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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An oral androgen receptor PROTAC degrader for prostate cancer
Neklesa, Taavi, Snyder, Lawrence B, Willard, Ryan R, Vitale, Nicholas, Raina, Kanak, Pizzano, Jennifer, Gordon, Deborah A, Bookbinder, Mark, Macaluso, Jennifer, Dong, Hanqing, Liu, Zheng, Ferraro, Caterina, Wang, Gan, Wang, Jing, Crews, Craig M, Houston, John, Crew, Andrew P, Taylor, Ian
Published in Journal of clinical oncology (20.02.2018)
Published in Journal of clinical oncology (20.02.2018)
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Abstract 5637: An oral Androgen Receptor PROTAC degrader for prostate cancer
Neklesa, Taavi K., Snyder, Lawrence B., Bookbinder, Mark, Chen, Xin, Crew, Andrew P., Crews, Craig M., Dong, Hanqing, Gordon, Deborah, Macaluso, Jennifer, Raina, Kanak, Rossi, AnnMarie, Taylor, Ian, Vitale, Nicholas, Wang, Jing, Willard, Ryan R., Zimmermann, Kurt
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Platelet-derived growth factor D: Tumorigenicity in mice and dysregulated expression in human cancer
LAROCHELLE, William J, JEFFERS, Michael, MAYOTTE, Jane, MACALUSO, Jennifer, RITTMAN, Beth, WU, Frank, DHANABAL, Mohan, HERRMANN, John, LICHENSTEIN, Henri S, CORVALAN, Jose R. F, JIA, Xiao-Chi, XIAO FENG, VANEGAS, Sandra, VICKROY, Justin D, YANG, Xiao-Dong, CHEN, Francine, GAZIT, Gadi
Published in Cancer research (Chicago, Ill.) (01.05.2002)
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Published in Cancer research (Chicago, Ill.) (01.05.2002)
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Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively
Raina, Kanak, Forbes, Chris D, Stronk, Rebecca, Rappi, Jr, Jonathan P, Eastman, Kyle J, Gerritz, Samuel W, Yu, Xinheng, Li, Hao, Bhardwaj, Amit, Forgione, Mia, Hundt, Abigail, King, Madeline P, Posner, Zoe M, Denny, Allison, McGovern, Andrew, Puleo, David E, Garvin, Ethan, Chenard, Rebekka, Zaware, Nilesh, Mousseau, James J, Macaluso, Jennifer, Martin, Michael, Bassoli, Kyle, Jones, Kelli, Garcia, Marco, Howard, Katia, Smith, Levi M, Chen, Jinshan M, De Leon, Cesar A, Hines, John, Kayser-Bricker, Katherine J, Crews, Craig M
Published in bioRxiv (02.01.2023)
Published in bioRxiv (02.01.2023)
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