A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas
Zender, Steffen, Nickeleit, Irina, Wuestefeld, Torsten, Sörensen, Inga, Dauch, Daniel, Bozko, Przemyslaw, El-Khatib, Mona, Geffers, Robert, Bektas, Hueseyin, Manns, Michael P., Gossler, Achim, Wilkens, Ludwig, Plentz, Ruben, Zender, Lars, Malek, Nisar P.
Published in Cancer cell (10.06.2013)
Published in Cancer cell (10.06.2013)
Get full text
Journal Article
Hypoxia induced Sonic Hedgehog signaling regulates cancer stemness, epithelial-to-mesenchymal transition and invasion in cholangiocarcinoma
Bhuria, Vikas, Xing, Jun, Scholta, Tim, Bui, Khac Cuong, Nguyen, Mai Ly Thi, Malek, Nisar P., Bozko, Przemyslaw, Plentz, Ruben R.
Published in Experimental cell research (15.12.2019)
Published in Experimental cell research (15.12.2019)
Get full text
Journal Article
Severe SARS-CoV-2 Infection Inhibits Fibrinolysis Leading to Changes in Viscoelastic Properties of Blood Clot: A Descriptive Study of Fibrinolysis in COVID-19
Hammer, Stefanie, Häberle, Helene, Schlensak, Christian, Bitzer, Michael, Malek, Nisar P., Handgretinger, Rupert, Lang, Peter, Hörber, Sebastian, Peter, Andreas, Martus, Peter, Mirakaj, Valbona, Gawaz, Meinrad, Geisler, Tobias, Althaus, Karina, Rosenberger, Peter, Bakchoul, Tamam
Published in Thrombosis and haemostasis (01.11.2021)
Published in Thrombosis and haemostasis (01.11.2021)
Get full text
Journal Article
A researcher's guide to preclinical mouse NASH models
Gallage, Suchira, Avila, Jose Efren Barragan, Ramadori, Pierluigi, Focaccia, Enrico, Rahbari, Mohammad, Ali, Adnan, Malek, Nisar P, Anstee, Quentin M, Heikenwalder, Mathias
Published in Nature metabolism (01.12.2022)
Published in Nature metabolism (01.12.2022)
Get more information
Journal Article
A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration
Wuestefeld, Torsten, Pesic, Marina, Rudalska, Ramona, Dauch, Daniel, Longerich, Thomas, Kang, Tae-Won, Yevsa, Tetyana, Heinzmann, Florian, Hoenicke, Lisa, Hohmeyer, Anja, Potapova, Anna, Rittelmeier, Ina, Jarek, Michael, Geffers, Robert, Scharfe, Maren, Klawonn, Frank, Schirmacher, Peter, Malek, Nisar P., Ott, Michael, Nordheim, Alfred, Vogel, Arndt, Manns, Michael P., Zender, Lars
Published in Cell (11.04.2013)
Published in Cell (11.04.2013)
Get full text
Journal Article
Ubiquitously expressed Human Beta Defensin 1 (hBD1) forms bacteria-entrapping nets in a redox dependent mode of action
Raschig, Judith, Mailänder-Sánchez, Daniela, Berscheid, Anne, Berger, Jürgen, Strömstedt, Adam A, Courth, Lioba F, Malek, Nisar P, Brötz-Oesterhelt, Heike, Wehkamp, Jan
Published in PLoS pathogens (01.03.2017)
Published in PLoS pathogens (01.03.2017)
Get full text
Journal Article
Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma – The SHELTER study
Bitzer, Michael, Horger, Marius, Giannini, Edoardo G, Ganten, Tom M, Wörns, Marcus A, Siveke, Jens T, Dollinger, Matthias M, Gerken, Guido, Scheulen, Max E, Wege, Henning, Zagonel, Vittorina, Cillo, Umberto, Trevisani, Franco, Santoro, Armando, Montesarchio, Vincenzo, Malek, Nisar P, Holzapfel, Julia, Herz, Thomas, Ammendola, Astrid S, Pegoraro, Stefano, Hauns, Bernhard, Mais, Anna, Lauer, Ulrich M, Henning, Stefan W, Hentsch, Bernd
Published in Journal of hepatology (01.08.2016)
Published in Journal of hepatology (01.08.2016)
Get full text
Journal Article
Quality of life in inflammatory bowel diseases: it is not all about the bowel
Keller, Ronald, Mazurak, Nazar, Fantasia, Laura, Fusco, Stefano, Malek, Nisar P, Wehkamp, Jan, Enck, Paul, Klag, Thomas
Published in Intestinal research (01.01.2021)
Published in Intestinal research (01.01.2021)
Get full text
Journal Article
Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis
Koeninger, Louis, Armbruster, Nicole S, Brinch, Karoline Sidelmann, Kjaerulf, Søren, Andersen, Birgitte, Langnau, Carolin, Autenrieth, Stella E, Schneidawind, Dominik, Stange, Eduard F, Malek, Nisar P, Nordkild, Peter, Jensen, Benjamin A H, Wehkamp, Jan
Published in Frontiers in immunology (31.01.2020)
Published in Frontiers in immunology (31.01.2020)
Get full text
Journal Article
Dysregulation of Carnosine Metabolism in Progression of Diseases
Bozko, Maria, Drozak, Jakub, Malek, Nisar P, Bozko, Przemyslaw
Published in Current medicinal chemistry (01.01.2020)
Published in Current medicinal chemistry (01.01.2020)
Get more information
Journal Article
The molecular interaction pattern of lenvatinib enables inhibition of wild-type or kinase-mutated FGFR2-driven cholangiocarcinoma
Spahn, Stephan, Kleinhenz, Fabian, Shevchenko, Ekaterina, Stahl, Aaron, Rasen, Yvonne, Geisler, Christine, Ruhm, Kristina, Klaumuenzer, Marion, Kronenberger, Thales, Laufer, Stefan A., Sundberg-Malek, Holly, Bui, Khac Cuong, Horger, Marius, Biskup, Saskia, Schulze-Osthoff, Klaus, Templin, Markus, Malek, Nisar P., Poso, Antti, Bitzer, Michael
Published in Nature communications (12.02.2024)
Published in Nature communications (12.02.2024)
Get full text
Journal Article
The German Network for Personalized Medicine to enhance patient care and translational research
Illert, A. L., Stenzinger, A., Bitzer, M., Horak, P., Gaidzik, V. I., Möller, Y., Beha, J., Öner, Ö., Schmitt, F., Laßmann, S., Ossowski, S., Schaaf, C. P., Hallek, M., Brümmendorf, T. H., Albers, P., Fehm, T., Brossart, P., Glimm, H., Schadendorf, D., Bleckmann, A., Brandts, C. H., Esposito, I., Mack, E., Peters, C., Bokemeyer, C., Fröhling, S., Kindler, T., Algül, H., Heinemann, V., Döhner, H., Bargou, R., Ellenrieder, V., Hillemanns, P., Lordick, F., Hochhaus, A., Beckmann, M. W., Pukrop, T., Trepel, M., Sundmacher, L., Wesselmann, S., Nettekoven, G., Kohlhuber, F., Heinze, O., Budczies, J., Werner, M., Nikolaou, K., Beer, A. J., Tabatabai, G., Weichert, W., Keilholz, U., Boerries, M., Kohlbacher, O., Duyster, J., Thimme, R., Seufferlein, T., Schirmacher, P., Malek, N. P.
Published in Nature medicine (01.06.2023)
Published in Nature medicine (01.06.2023)
Get full text
Journal Article
Clinical and Genetic Tumor Characteristics of Responding and Non-Responding Patients to PD-1 Inhibition in Hepatocellular Carcinoma
Spahn, Stephan, Roessler, Daniel, Pompilia, Radu, Gabernet, Gisela, Gladstone, Beryl Primrose, Horger, Marius, Biskup, Saskia, Feldhahn, Magdalena, Nahnsen, Sven, Hilke, Franz J, Scheiner, Bernhard, Dufour, Jean-François, De Toni, Enrico N, Pinter, Matthias, Malek, Nisar P, Bitzer, Michael
Published in Cancers (18.12.2020)
Published in Cancers (18.12.2020)
Get full text
Journal Article
The SCF-Fbxw5 E3-ubiquitin ligase is regulated by Plk4 and targets HsSAS-6 to control centrosome duplication
Malek, Nisar P, Puklowski, Anja, Homsi, Yahya, Keller, Debora, May, Martin, Chauhan, Sangeeta, Kossatz, Uta, Grünwald, Viktor, Kubicka, Stefan, Pich, Andreas, Manns, Michael P, Hoffmann, Ingrid, Gönczy, Pierre
Published in Nature cell biology (01.08.2011)
Published in Nature cell biology (01.08.2011)
Get full text
Journal Article
Second-generation direct-acting-antiviral hepatitis C virus treatment: Efficacy, safety, and predictors of SVR12
Werner, Christoph R, Schwarz, Julia M, Egetemeyr, Daniel P, Beck, Robert, Malek, Nisar P, Lauer, Ulrich M, Berg, Christoph P
Published in World journal of gastroenterology : WJG (21.09.2016)
Published in World journal of gastroenterology : WJG (21.09.2016)
Get full text
Journal Article