Advances in Acute Myeloid Leukemia: Recently Approved Therapies and Drugs in Development
Stanchina, Michele, Soong, Deborah, Zheng-Lin, Binbin, Watts, Justin M, Taylor, Justin
Published in Cancers (01.11.2020)
Published in Cancers (01.11.2020)
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A Phase 1B Clinical Study of Combretastatin A1 Diphosphate (OXi4503) and Cytarabine (ARA-C) in Combination (OXA) for Patients with Relapsed or Refractory Acute Myeloid Leukemia
Uckun, Fatih M, Cogle, Christopher R, Lin, Tara L, Qazi, Sanjive, Trieu, Vuong N, Schiller, Gary, Watts, Justin M
Published in Cancers (26.12.2019)
Published in Cancers (26.12.2019)
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KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study
Swords, Ronan T., MD, PhD, FRCPI, FRCPath, Greenberg, Peter L., MD, Wei, Andrew H., MBBS, PhD, Durrant, Simon, MBBS, MRCS, LRCP, FRCP, FRCPath, Advani, Anjali S., MD, Hertzberg, Mark S., MBBS, PhD, FRACP, FRCPA, Lewis, Ian D., MBBS, PhD, Rivera, Gabriel, MD, Gratzinger, Dita, MD, PhD, Fan, Alice C., MD, Felsher, Dean W., MD, PhD, Cortes, Jorge E., MD, Watts, Justin M., MD, Yarranton, Geoff T., PhD, Walling, Jackie M., MB, ChB, PhD, Lancet, Jeffrey E., MD
Published in Leukemia research (01.11.2016)
Published in Leukemia research (01.11.2016)
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A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy
Watts, Justin M, Perez, Aymee, Pereira, Lutecia, Fan, Yao-Shan, Brown, Geoffrey, Vega, Francisco, Petrie, Kevin, Swords, Ronan T, Zelent, Arthur
Published in International journal of molecular sciences (11.07.2017)
Published in International journal of molecular sciences (11.07.2017)
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Telomere Length and Associations with Somatic Mutations and Clinical Outcomes in Acute Myeloid Leukemia
Watts, Justin M., MD, Dumitriu, Bogdan, MD, Hilden, Patrick, MS, Kishtagari, Ashwin, MD, Rapaport, Franck, PhD, Chen, Christina, BS, Ahn, Jihae, Devlin, Sean M., PhD, Stein, Eytan M., MD, Rampal, Raajit, Levine, Ross L., MD, Young, Neal, MD, Tallman, Martin S., MD
Published in Leukemia research (01.10.2016)
Published in Leukemia research (01.10.2016)
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Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia
Roboz, Gail J., DiNardo, Courtney D., Stein, Eytan M., de Botton, Stéphane, Mims, Alice S., Prince, Gabrielle T., Altman, Jessica K., Arellano, Martha L., Donnellan, Will, Erba, Harry P., Mannis, Gabriel N., Pollyea, Daniel A., Stein, Anthony S., Uy, Geoffrey L., Watts, Justin M., Fathi, Amir T., Kantarjian, Hagop M., Tallman, Martin S., Choe, Sung, Dai, David, Fan, Bin, Wang, Hongfang, Zhang, Vickie, Yen, Katharine E., Kapsalis, Stephanie M., Hickman, Denice, Liu, Hua, Agresta, Samuel V., Wu, Bin, Attar, Eyal C., Stone, Richard M.
Published in Blood (13.02.2020)
Published in Blood (13.02.2020)
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Corrigendum to “KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study” [Leuk. Res. 50 (Nov) (2016) 123–131. PubMed PMID: 27736729]
Swords, Ronan T., MD, PhD, Greenberg, Peter L., MD, Wei, Andrew H., MBBS, PhD, Durrant, Simon, MBBS, Advani, Anjali S., MD, Hertzberg, Mark S., MBBS, PhD, Lewis, Ian D., MBBS, PhD, Rivera, Gabriel, MD, Gratzinger, Dita, MD, PhD, Fan, Alice C., MD, Felsher, Dean W., MD, PhD, Cortes, Jorge E., MD, Watts, Justin M., MD, Yarranton, Geoff T., PhD, Walling, Jackie M., MB, ChB, PhD, Lancet, Jeffrey E., MD
Published in Leukemia research (01.08.2017)
Published in Leukemia research (01.08.2017)
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Clinical Responsiveness to All-trans Retinoic Acid Is Potentiated by LSD1 Inhibition and Associated with a Quiescent Transcriptome in Myeloid Malignancies
Tayari, Mina M, Santos, Helena G Dos, Kwon, Deukwoo, Bradley, Terrence J, Thomassen, Amber, Chen, Charles, Dinh, Yvonne, Perez, Aymee, Zelent, Arthur, Morey, Lluis, Cimmino, Luisa, Shiekhattar, Ramin, Swords, Ronan T, Watts, Justin M
Published in Clinical cancer research (01.04.2021)
Published in Clinical cancer research (01.04.2021)
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Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial
Gangat, Naseema, Marinaccio, Christian, Swords, Ronan, Watts, Justin M, Gurbuxani, Sandeep, Rademaker, Alfred, Fought, Angela J, Frankfurt, Olga, Altman, Jessica K, Wen, Qiang Jeremy, Farnoud, Noushin, Famulare, Christopher A, Patel, Akshar, Tapia, Roberto, Vallapureddy, Rangit R, Barath, Stephanie, Graf, Amy, Handlogten, Amy, Zblewski, Darci, Patnaik, Mrinal M, Al-Kali, Aref, Dinh, Yvonne Trang, Englund Prahl, Kristen, Patel, Shradha, Nobrega, Juan Carlos, Tejera, Dalissa, Thomassen, Amber, Gao, Juehua, Ji, Peng, Rampal, Raajit K, Giles, Francis J, Tefferi, Ayalew, Stein, Brady, Crispino, John D
Published in Clinical cancer research (15.08.2019)
Published in Clinical cancer research (15.08.2019)
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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML
Choe, Sung, Wang, Hongfang, DiNardo, Courtney D., Stein, Eytan M., de Botton, Stéphane, Roboz, Gail J., Altman, Jessica K., Mims, Alice S., Watts, Justin M., Pollyea, Daniel A., Fathi, Amir T., Tallman, Martin S., Kantarjian, Hagop M., Stone, Richard M., Quek, Lynn, Konteatis, Zenon, Dang, Lenny, Nicolay, Brandon, Nejad, Parham, Liu, Guowen, Zhang, Vickie, Liu, Hua, Goldwasser, Meredith, Liu, Wei, Marks, Kevin, Bowden, Chris, Biller, Scott A., Attar, Eyal C., Wu, Bin
Published in Blood advances (12.05.2020)
Published in Blood advances (12.05.2020)
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Molecular annotation of extramedullary acute myeloid leukemia identifies high prevalence of targetable mutations
Ball, Somedeb, Knepper, Todd C., Deutsch, Yehuda E., Samra, Wassim, Watts, Justin M., Bradley, Terrence J., Chan, Onyee, Hussaini, Mohammad Omar, Zhang, Ling, Sweet, Kendra L., Kuykendall, Andrew T., Talati, Chetasi, Padron, Eric, Komrokji, Rami S., Lancet, Jeffrey E., Sallman, David A.
Published in Cancer (01.11.2022)
Published in Cancer (01.11.2022)
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Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies
Taylor, Justin, Pavlick, Dean, Yoshimi, Akihide, Marcelus, Christina, Chung, Stephen S, Hechtman, Jaclyn F, Benayed, Ryma, Cocco, Emiliano, Durham, Benjamin H, Bitner, Lillian, Inoue, Daichi, Chung, Young Rock, Mullaney, Kerry, Watts, Justin M, Diamond, Eli L, Albacker, Lee A, Mughal, Tariq I, Ebata, Kevin, Tuch, Brian B, Ku, Nora, Scaltriti, Maurizio, Roshal, Mikhail, Arcila, Maria, Ali, Siraj, Hyman, David M, Park, Jae H, Abdel-Wahab, Omar
Published in The Journal of clinical investigation (01.09.2018)
Published in The Journal of clinical investigation (01.09.2018)
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Olutasidenib alone or with azacitidine in IDH1-mutated acute myeloid leukaemia and myelodysplastic syndrome: phase 1 results of a phase 1/2 trial
Watts, Justin M, Baer, Maria R, Yang, Jay, Prebet, Thomas, Lee, Sangmin, Schiller, Gary J, Dinner, Shira N, Pigneux, Arnaud, Montesinos, Pau, Wang, Eunice S, Seiter, Karen P, Wei, Andrew H, De Botton, Stephane, Arnan, Montserrat, Donnellan, Will, Schwarer, Anthony P, Récher, Christian, Jonas, Brian A, Ferrell, Jr, P Brent, Marzac, Christophe, Kelly, Patrick, Sweeney, Jennifer, Forsyth, Sanjeev, Guichard, Sylvie M, Brevard, Julie, Henrick, Patrick, Mohamed, Hesham, Cortes, Jorge E
Published in The Lancet. Haematology (01.01.2023)
Published in The Lancet. Haematology (01.01.2023)
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Olutasidenib in post-venetoclax patients with mutant isocitrate dehydrogenase 1 (m IDH1 ) acute myeloid leukemia (AML)
Cortes, Jorge, Jonas, Brian A, Schiller, Gary, Mims, Alice, Roboz, Gail J, Wei, Andrew H, Montesinos, Pau, Ferrell, P Brent, Yee, Karen Wl, Fenaux, Pierre, Schwarer, Anthony, Watts, Justin M
Published in Leukemia & lymphoma (01.08.2024)
Published in Leukemia & lymphoma (01.08.2024)
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Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant
DiNardo, Courtney D., Stein, Eytan M., Pigneux, Arnaud, Altman, Jessica K., Collins, Robert, Erba, Harry P., Watts, Justin M., Uy, Geoffrey L., Winkler, Thomas, Wang, Hongfang, Choe, Sung, Liu, Hua, Wu, Bin, Kapsalis, Stephanie M., Roboz, Gail J., de Botton, Stéphane
Published in Leukemia (01.11.2021)
Published in Leukemia (01.11.2021)
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Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study
Swords, Ronan T., Azzam, Diana, Al-Ali, Hassan, Lohse, Ines, Volmar, Claude-Henry, Watts, Justin M., Perez, Aymee, Rodriguez, Ana, Vargas, Fernando, Elias, Roy, Vega, Francisco, Zelent, Arthur, Brothers, Shaun P., Abbasi, Taher, Trent, Jonathan, Rangwala, Shaukat, Deutsch, Yehuda, Conneally, Eibhlin, Drusbosky, Leylah, Cogle, Christopher R., Wahlestedt, Claes
Published in Leukemia research (01.01.2018)
Published in Leukemia research (01.01.2018)
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Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML
de Botton, Stéphane, Fenaux, Pierre, Yee, Karen, Récher, Christian, Wei, Andrew H., Montesinos, Pau, Taussig, David C., Pigneux, Arnaud, Braun, Thorsten, Curti, Antonio, Grove, Carolyn, Jonas, Brian A., Khwaja, Asim, Legrand, Ollivier, Peterlin, Pierre, Arnan, Montserrat, Blum, William, Cilloni, Daniela, Hiwase, Devendra K., Jurcic, Joseph G., Krauter, Jürgen, Thomas, Xavier, Watts, Justin M., Yang, Jay, Polyanskaya, Olga, Brevard, Julie, Sweeney, Jennifer, Barrett, Emma, Cortes, Jorge
Published in Blood advances (11.07.2023)
Published in Blood advances (11.07.2023)
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