Antarctic ice-sheet sensitivity to obliquity forcing enhanced through ocean connections
Levy, R. H., Meyers, S. R., Naish, T. R., Golledge, N. R., McKay, R. M., Crampton, J. S., DeConto, R. M., De Santis, L., Florindo, F., Gasson, E. G. W., Harwood, D. M., Luyendyk, B. P., Powell, R. D., Clowes, C., Kulhanek, D. K.
Published in Nature geoscience (01.02.2019)
Published in Nature geoscience (01.02.2019)
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Journal Article
Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption
Harwood, M. D., Neuhoff, S., Carlson, G. L., Warhurst, G., Rostami-Hodjegan, A.
Published in Biopharmaceutics & drug disposition (01.01.2013)
Published in Biopharmaceutics & drug disposition (01.01.2013)
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Journal Article
Antarctic records of precession-paced insolation-driven warming during early Pleistocene Marine Isotope Stage 31
Scherer, R. P., Bohaty, S. M., Dunbar, R. B., Esper, O., Flores, J.-A., Gersonde, R., Harwood, D. M., Roberts, A. P., Taviani, M.
Published in Geophysical research letters (01.02.2008)
Published in Geophysical research letters (01.02.2008)
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Journal Article
Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions
Burt, H.J., Neuhoff, S., Almond, L., Gaohua, L., Harwood, M.D., Jamei, M., Rostami-Hodjegan, A., Tucker, G.T., Rowland-Yeo, K.
Published in European journal of pharmaceutical sciences (10.06.2016)
Published in European journal of pharmaceutical sciences (10.06.2016)
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Journal Article
Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
Burt, Howard J, Riedmaier, Arian Emami, Harwood, Matthew D, Crewe, H Kim, Gill, Katherine L, Neuhoff, Sibylle
Published in Drug metabolism and disposition (01.10.2016)
Published in Drug metabolism and disposition (01.10.2016)
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Journal Article
In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
Harwood, Matthew D, Achour, Brahim, Neuhoff, Sibylle, Russell, Matthew R, Carlson, Gordon, Warhurst, Geoffrey
Published in Drug metabolism and disposition (01.03.2016)
Published in Drug metabolism and disposition (01.03.2016)
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Journal Article
Investigation of Regional Mechanisms Responsible for Poor Oral Absorption in Humans of a Modified Release Preparation of the α-Adrenoreceptor Antagonist, 4-Amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003) : The Rational Use of ex Vivo Intestine to Predict in Vivo Absorption
COLLETT, A, STEPHENS, R. H, HARWOOD, M. D, HUMPHREY, M, DALLMAN, L, BENNETT, J, DAVIS, J, CARLSON, G. L, WARHURST, G
Published in Drug metabolism and disposition (2008)
Published in Drug metabolism and disposition (2008)
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Journal Article
Application of an LC–MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique
Harwood, M.D., Achour, B., Russell, M.R., Carlson, G.L., Warhurst, G., Rostami-Hodjegan, A.
Published in Journal of pharmaceutical and biomedical analysis (10.06.2015)
Published in Journal of pharmaceutical and biomedical analysis (10.06.2015)
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Journal Article
In Vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
Harwood, Matthew D, Achour, Brahim, Neuhoff, Sibylle, Russell, Matthew R, Carlson, Gordon, Warhurst, Geoffrey, Rostami-Hodjegan, Amin
Published in Drug metabolism and disposition (01.03.2016)
Published in Drug metabolism and disposition (01.03.2016)
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Journal Article
A sedimentological record of early Miocene ice advance and retreat, AND-2A drill hole, McMurdo Sound, Antarctica
Field, B. D, Browne, G. H, Fielding, C. R, Florindo, F, Harwood, D. M, Judge, S. A, Krissek, L. A, Panter, K. S, Passchier, S, Pekar, S. F, Sandroni, S, Talarico, F. M
Published in Geosphere (Boulder, Colo.) (01.08.2018)
Published in Geosphere (Boulder, Colo.) (01.08.2018)
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Journal Article
Suicide in older people: mode of death, demographic factors, and medical contact before death
Harwood, Daniel Michael James, Hawton, Keith, Hope, Tony, Jacoby, Robin
Published in International journal of geriatric psychiatry (01.08.2000)
Published in International journal of geriatric psychiatry (01.08.2000)
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Journal Article
Conference Proceeding
Glaciation across the Oligocene–Miocene boundary in southern McMurdo Sound, Antarctica: new chronology from the CIROS-1 drill hole
Roberts, Andrew P., Wilson, Gary S., Harwood, David M., Verosub, Kenneth L.
Published in Palaeogeography, palaeoclimatology, palaeoecology (15.09.2003)
Published in Palaeogeography, palaeoclimatology, palaeoecology (15.09.2003)
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Journal Article
New Seismic Methods to Support Sea-Ice Platform Drilling
Speece, M. A., Levy, R. H., Harwood, D. M., Pekar, S. F., Powell, R. D.
Published in Scientific drilling (Hokkaido, Japan) (01.03.2009)
Published in Scientific drilling (Hokkaido, Japan) (01.03.2009)
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Journal Article
Predicting the outcome of acute stroke: prospective evaluation of five multivariate models and comparison with simple methods
Gladman, J R, Harwood, D M, Barer, D H
Published in Journal of neurology, neurosurgery and psychiatry (01.05.1992)
Published in Journal of neurology, neurosurgery and psychiatry (01.05.1992)
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Journal Article
Conference Proceeding