Dengue vaccine breakthrough infections reveal properties of neutralizing antibodies linked to protection
Henein, Sandra, Adams, Cameron, Bonaparte, Matthew, Moser, Janice M, Munteanu, Alina, Baric, Ralph, Desilva, Aravinda M
Published in The Journal of clinical investigation (01.07.2021)
Published in The Journal of clinical investigation (01.07.2021)
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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
Grifoni, Alba, Weiskopf, Daniela, Ramirez, Sydney I., Mateus, Jose, Dan, Jennifer M., Moderbacher, Carolyn Rydyznski, Rawlings, Stephen A., Sutherland, Aaron, Premkumar, Lakshmanane, Jadi, Ramesh S., Marrama, Daniel, de Silva, Aravinda M., Frazier, April, Carlin, Aaron F., Greenbaum, Jason A., Peters, Bjoern, Krammer, Florian, Smith, Davey M., Crotty, Shane, Sette, Alessandro
Published in Cell (25.06.2020)
Published in Cell (25.06.2020)
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Dengue virus infection elicits highly polarized CX3CR1⁺ cytotoxic CD4⁺ T cells associated with protective immunity
Weiskopf, Daniela, Bangs, Derek J., Sidney, John, Kolla, Ravi V., De Silva, Aruna D., de Silva, Aravinda M., Crotty, Shane, Peters, Bjoern, Sette, Alessandro
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2015)
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Zika virus infection enhances future risk of severe dengue disease
Katzelnick, Leah C, Narvaez, César, Arguello, Sonia, Lopez Mercado, Brenda, Collado, Damaris, Ampie, Oscarlett, Elizondo, Douglas, Miranda, Tatiana, Bustos Carillo, Fausto, Mercado, Juan Carlos, Latta, Krista, Schiller, Amy, Segovia-Chumbez, Bruno, Ojeda, Sergio, Sanchez, Nery, Plazaola, Miguel, Coloma, Josefina, Halloran, M Elizabeth, Premkumar, Lakshmanane, Gordon, Aubree, Narvaez, Federico, de Silva, Aravinda M, Kuan, Guillermina, Balmaseda, Angel, Harris, Eva
Published in Science (American Association for the Advancement of Science) (28.08.2020)
Published in Science (American Association for the Advancement of Science) (28.08.2020)
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Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection
Collins, Matthew H, McGowan, Eileen, Jadi, Ramesh, Young, Ellen, Lopez, Cesar A, Baric, Ralph S, Lazear, Helen M, de Silva, Aravinda M
Published in Emerging infectious diseases (01.05.2017)
Published in Emerging infectious diseases (01.05.2017)
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A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans
Nivarthi, Usha K., Swanstrom, Jesica, Delacruz, Matthew J., Patel, Bhumi, Durbin, Anna P., Whitehead, Steve S., Kirkpatrick, Beth D., Pierce, Kristen K., Diehl, Sean A., Katzelnick, Leah, Baric, Ralph S., de Silva, Aravinda M.
Published in Nature communications (17.02.2021)
Published in Nature communications (17.02.2021)
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The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
Premkumar, Lakshmanane, Segovia-Chumbez, Bruno, Jadi, Ramesh, Martinez, David R, Raut, Rajendra, Markmann, Alena, Cornaby, Caleb, Bartelt, Luther, Weiss, Susan, Park, Yara, Edwards, Caitlin E, Weimer, Eric, Scherer, Erin M, Rouphael, Nadine, Edupuganti, Srilatha, Weiskopf, Daniela, Tse, Longping V, Hou, Yixuan J, Margolis, David, Sette, Alessandro, Collins, Matthew H, Schmitz, John, Baric, Ralph S, de Silva, Aravinda M
Published in Science Immunology (11.06.2020)
Published in Science Immunology (11.06.2020)
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Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera
de Alwis, Ruklanthi, Williams, Katherine L, Schmid, Michael A, Lai, Chih-Yun, Patel, Bhumi, Smith, Scott A, Crowe, James E, Wang, Wei-Kung, Harris, Eva, de Silva, Aravinda M
Published in PLoS pathogens (01.10.2014)
Published in PLoS pathogens (01.10.2014)
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Longitudinal Analysis of Antibody Cross-neutralization Following Zika Virus and Dengue Virus Infection in Asia and the Americas
Montoya, Magelda, Collins, Matthew, Dejnirattisai, Wanwisa, Katzelnick, Leah C, Puerta-Guardo, Henry, Jadi, Ramesh, Schildhauer, Samuel, Supasa, Piyada, Vasanawathana, Sirijitt, Malasit, Prida, Mongkolsapaya, Juthathip, de Silva, Aruna D, Tissera, Hasitha, Balmaseda, Angel, Screaton, Gavin, de Silva, Aravinda M, Harris, Eva
Published in The Journal of infectious diseases (13.07.2018)
Published in The Journal of infectious diseases (13.07.2018)
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Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? The Path to a Dengue Vaccine: Learning from Human Natural Dengue Infection Studies and Vaccine Trials
de Silva, Aravinda M, Harris, Eva
Published in Cold Spring Harbor perspectives in biology (01.06.2018)
Published in Cold Spring Harbor perspectives in biology (01.06.2018)
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Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika
Andrade, Paulina, Gimblet-Ochieng, Ciara, Modirian, Faraz, Collins, Matthew, Cárdenas, Maritza, Katzelnick, Leah C., Montoya, Magelda, Michlmayr, Daniela, Kuan, Guillermina, Balmaseda, Angel, Coloma, Josefina, de Silva, Aravinda M., Harris, Eva
Published in Nature communications (26.02.2019)
Published in Nature communications (26.02.2019)
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Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus
Adams, Cameron, Carbaugh, Derek L, Shu, Bo, Ng, Thiam-Seng, Castillo, Izabella N, Bhowmik, Ryan, Segovia-Chumbez, Bruno, Puhl, Ana C, Graham, Stephen, Diehl, Sean A, Lazear, Helen M, Lok, Shee-Mei, de Silva, Aravinda M, Premkumar, Lakshmanane
Published in PLoS pathogens (01.01.2023)
Published in PLoS pathogens (01.01.2023)
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Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8⁺ T cells
Weiskopf, Daniela, Angelo, Michael A, de Azeredo, Elzinandes L, Sidney, John, Greenbaum, Jason A, Fernando, Anira N, Broadwater, Anne, Kolla, Ravi V, De Silva, Aruna D, de Silva, Aravinda M, Mattia, Kimberly A, Doranz, Benjamin J, Grey, Howard M, Shresta, Sujan, Peters, Bjoern, Sette, Alessandro
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.2013)
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A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins
Fibriansah, Guntur, Tan, Joanne L., Smith, Scott A., de Alwis, Ruklanthi, Ng, Thiam-Seng, Kostyuchenko, Victor A., Jadi, Ramesh S., Kukkaro, Petra, de Silva, Aravinda M., Crowe, James E., Lok, Shee-Mei
Published in Nature communications (20.02.2015)
Published in Nature communications (20.02.2015)
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Dengue type 1 viruses circulating in humans are highly infectious and poorly neutralized by human antibodies
Raut, Rajendra, Corbett, Kizzmekia S., Tennekoon, Rashika N., Premawansa, Sunil, Wijewickrama, Ananda, Premawansa, Gayani, Mieczkowski, Piotr, Rückert, Claudia, Ebel, Gregory D., De Silva, Aruna D., de Silva, Aravinda M.
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2019)
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Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions
de Alwis, Ruklanthi, Smith, Scott A, Olivarez, Nicholas P, Messer, William B, Huynh, Jeremy P, Wahala, Wahala M. P. B, White, Laura J, Diamond, Michael S, Baric, Ralph S, Crowe, James E., Jr, de Silva, Aravinda M
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (08.05.2012)
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Maternal Height and Child Growth Patterns
Addo, O. Yaw, PhD, Stein, Aryeh D., PhD, Fall, Caroline H., DM, Gigante, Denise P., PhD, Guntupalli, Aravinda M., PhD, Horta, Bernardo L., PhD, Kuzawa, Christopher W., PhD, Lee, Nanette, PhD, Norris, Shane A., PhD, Prabhakaran, Poornima, MBBS, Richter, Linda M., PhD, Sachdev, Harshpal S., MD, Martorell, Reynaldo, PhD
Published in The Journal of pediatrics (01.08.2013)
Published in The Journal of pediatrics (01.08.2013)
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Dissecting Antibodies Induced by a Chimeric Yellow Fever–Dengue, Live-Attenuated, Tetravalent Dengue Vaccine (CYD-TDV) in Naive and Dengue-Exposed Individuals
Henein, Sandra, Swanstrom, Jesica, Byers, Anthony M., Moser, Janice M., Shaik, S. Farzana, Bonaparte, Matthew, Jackson, Nicholas, Guy, Bruno, Baric, Ralph, de Silva, Aravinda M.
Published in The Journal of infectious diseases (01.02.2017)
Published in The Journal of infectious diseases (01.02.2017)
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Antigenic Variation of the Dengue Virus 2 Genotypes Impacts the Neutralization Activity of Human Antibodies in Vaccinees
Martinez, David R., Yount, Boyd, Nivarthi, Usha, Munt, Jennifer E., Delacruz, Matthew J., Whitehead, Stephen S., Durbin, Anna P., de Silva, Aravinda M., Baric, Ralph S.
Published in Cell reports (Cambridge) (06.10.2020)
Published in Cell reports (Cambridge) (06.10.2020)
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