Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia
Rupert, Joseph E, Narasimhan, Ashok, Jengelley, Daenique H A, Jiang, Yanlin, Liu, Jianguo, Au, Ernie, Silverman, Libbie M, Sandusky, George, Bonetto, Andrea, Cao, Sha, Lu, Xiaoyu, O'Connell, Thomas M, Liu, Yunlong, Koniaris, Leonidas G, Zimmers, Teresa A
Published in The Journal of experimental medicine (07.06.2021)
Published in The Journal of experimental medicine (07.06.2021)
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A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation
Wagner, Gregory R, Bhatt, Dhaval P, O'Connell, Thomas M, Thompson, J Will, Dubois, Laura G, Backos, Donald S, Yang, Hao, Mitchell, Grant A, Ilkayeva, Olga R, Stevens, Robert D, Grimsrud, Paul A, Hirschey, Matthew D
Published in Cell metabolism (04.04.2017)
Published in Cell metabolism (04.04.2017)
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Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut
Reese, Aspen T, Cho, Eugenia H, Klitzman, Bruce, Nichols, Scott P, Wisniewski, Natalie A, Villa, Max M, Durand, Heather K, Jiang, Sharon, Midani, Firas S, Nimmagadda, Sai N, O'Connell, Thomas M, Wright, Justin P, Deshusses, Marc A, David, Lawrence A
Published in eLife (19.06.2018)
Published in eLife (19.06.2018)
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AMP deamination is sufficient to replicate an atrophy-like metabolic phenotype in skeletal muscle
Miller, Spencer G., Hafen, Paul S., Law, Andrew S., Springer, Catherine B., Logsdon, David L., O'Connell, Thomas M., Witczak, Carol A., Brault, Jeffrey J.
Published in Metabolism, clinical and experimental (01.10.2021)
Published in Metabolism, clinical and experimental (01.10.2021)
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Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study
Pourafshar, Shirin, Nicchitta, Mira, Tyson, Crystal C, Svetkey, Laura P, Corcoran, David L, Bain, James R, Muehlbauer, Michael J, Ilkayeva, Olga, O’Connell, Thomas M, Lin, Pao-Hwa, Scialla, Julia J
Published in Nutrients (22.05.2021)
Published in Nutrients (22.05.2021)
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Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia
Ballarò, Riccardo, Lopalco, Patrizia, Audrito, Valentina, Beltrà, Marc, Pin, Fabrizio, Angelini, Roberto, Costelli, Paola, Corcelli, Angela, Bonetto, Andrea, Szeto, Hazel H, O'Connell, Thomas M, Penna, Fabio
Published in Cancers (18.02.2021)
Published in Cancers (18.02.2021)
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Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation
Sampey, Brante P, Freemerman, Alex J, Zhang, Jimmy, Kuan, Pei-Fen, Galanko, Joseph A, O'Connell, Thomas M, Ilkayeva, Olga R, Muehlbauer, Michael J, Stevens, Robert D, Newgard, Christopher B, Brauer, Heather A, Troester, Melissa A, Makowski, Liza
Published in PloS one (12.06.2012)
Published in PloS one (12.06.2012)
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Feeding strategy shapes gut metagenomic enrichment and functional specialization in captive lemurs
McKenney, E. A., O'Connell, Thomas M., Rodrigo, Allen, Yoder, Anne D.
Published in Gut microbes (04.05.2018)
Published in Gut microbes (04.05.2018)
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Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation
Fannin, Rick D., Russo, Mark, O'Connell, Thomas M., Gerrish, Kevin, Winnike, Jason H., Macdonald, Jeffrey, Newton, Jack, Malik, Shahid, Sieber, Stella O., Parker, Joel, Shah, Ruchir, Zhou, Tong, Watkins, Paul B., Paules, Richard S.
Published in Hepatology (Baltimore, Md.) (01.01.2010)
Published in Hepatology (Baltimore, Md.) (01.01.2010)
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A role for gut microbiota in host niche differentiation
Greene, Lydia K., Williams, Cathy V., Junge, Randall E., Mahefarisoa, Karine L., Rajaonarivelo, Tsiky, Rakotondrainibe, Hajanirina, O’Connell, Thomas M., Drea, Christine M.
Published in The ISME Journal (01.07.2020)
Published in The ISME Journal (01.07.2020)
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A Comparison of Transcriptomic and Metabonomic Technologies for Identifying Biomarkers Predictive of Two-Year Rodent Cancer Bioassays
Thomas, Russell S., O'Connell, Thomas M., Pluta, Linda, Wolfinger, Russell D., Yang, Longlong, Page, Todd J.
Published in Toxicological sciences (01.03.2007)
Published in Toxicological sciences (01.03.2007)
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Metabolomics analysis reveals dysregulation in one carbon metabolism in Friedreich Ataxia
O'Connell, Thomas M, Logsdon, David L, Payne, R Mark
Published in Molecular genetics and metabolism (01.08.2022)
Published in Molecular genetics and metabolism (01.08.2022)
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Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure
Younge, Noelle E., Newgard, Christopher B., Cotten, C. Michael, Goldberg, Ronald N., Muehlbauer, Michael J., Bain, James R., Stevens, Robert D., O’Connell, Thomas M., Rawls, John F., Seed, Patrick C., Ashley, Patricia L.
Published in Scientific reports (03.06.2019)
Published in Scientific reports (03.06.2019)
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PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia
Pin, Fabrizio, Novinger, Leah J, Huot, Joshua R, Harris, Robert A, Couch, Marion E, O'Connell, Thomas M, Bonetto, Andrea
Published in The FASEB journal (01.06.2019)
Published in The FASEB journal (01.06.2019)
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