Continuous countercurrent chromatographic twin‐column purification of oligonucleotides: The role of the displacement effect
Fioretti, Ismaele, Müller‐Späth, Thomas, Weldon, Richard, Vogg, Sebastian, Morbidelli, Massimo, Sponchioni, Mattia
Published in Biotechnology and bioengineering (01.07.2022)
Published in Biotechnology and bioengineering (01.07.2022)
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Journal Article
Model‐assisted process characterization and validation for a continuous two‐column protein A capture process
Baur, Daniel, Angelo, James, Chollangi, Srinivas, Müller‐Späth, Thomas, Xu, Xuankuo, Ghose, Sanchayita, Li, Zheng Jian, Morbidelli, Massimo
Published in Biotechnology and bioengineering (01.01.2019)
Published in Biotechnology and bioengineering (01.01.2019)
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Journal Article
Virus clearance validation across continuous capture chromatography
Angelo, James, Chollangi, Srinivas, Müller‐Späth, Thomas, Jusyte, Simona, Xu, Xuankuo, Ghose, Sanchayita, Li, Zhengjian
Published in Biotechnology and bioengineering (01.09.2019)
Published in Biotechnology and bioengineering (01.09.2019)
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Journal Article
Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification
Catani, Martina, De Luca, Chiara, Medeiros Garcia Alcântara, João, Manfredini, Nicolò, Perrone, Daniela, Marchesi, Elena, Weldon, Richard, Müller-Späth, Thomas, Cavazzini, Alberto, Morbidelli, Massimo, Sponchioni, Mattia
Published in Biotechnology journal (01.08.2020)
Published in Biotechnology journal (01.08.2020)
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Journal Article
Model assisted comparison of Protein A resins and multi-column chromatography for capture processes
Baur, Daniel, Angelo, James M., Chollangi, Srinivas, Xu, Xuankuo, Müller-Späth, Thomas, Zhang, Na, Ghose, Sanchayita, Li, Zheng Jian, Morbidelli, Massimo
Published in Journal of biotechnology (10.11.2018)
Published in Journal of biotechnology (10.11.2018)
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Journal Article
Optimal model-based design of the twin-column CaptureSMB process improves capacity utilization and productivity in protein A affinity capture
Baur, Daniel, Angarita, Monica, Müller-Späth, Thomas, Morbidelli, Massimo
Published in Biotechnology journal (01.01.2016)
Published in Biotechnology journal (01.01.2016)
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Journal Article
Aggregation Stability of a Monoclonal Antibody During Downstream Processing
Arosio, Paolo, Barolo, Giuliano, Müller-Späth, Thomas, Wu, Hua, Morbidelli, Massimo
Published in Pharmaceutical research (01.08.2011)
Published in Pharmaceutical research (01.08.2011)
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Journal Article
multifraction separation in countercurrent chromatography (MCSGP)
Krättli, Martin, Müller-Späth, Thomas, Morbidelli, Massimo
Published in Biotechnology and bioengineering (01.09.2013)
Published in Biotechnology and bioengineering (01.09.2013)
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Journal Article
Separation of Lanthanides by Continuous Chromatography
Krättli, Martin, Müller-Späth, Thomas, Ulmer, Nicole, Ströhlein, Guido, Morbidelli, Massimo
Published in Industrial & engineering chemistry research (03.07.2013)
Published in Industrial & engineering chemistry research (03.07.2013)
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Journal Article
In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells
Arosio, Paolo, Owczarz, Marta, Müller-Späth, Thomas, Rognoni, Paola, Beeg, Marten, Wu, Hua, Salmona, Mario, Morbidelli, Massimo
Published in PloS one (14.03.2012)
Published in PloS one (14.03.2012)
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Journal Article
Integrated multidimensional chromatography on preparative scale for oligonucleotides purification
Nosengo, Chiara, Bozza, Desiree, Lievore, Giulio, Vogg, Sebastian, Catani, Martina, Cavazzini, Alberto, Müller-Späth, Thomas, De Luca, Chiara, Felletti, Simona
Published in Journal of Chromatography A (22.11.2024)
Published in Journal of Chromatography A (22.11.2024)
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Journal Article