Unimolecular Polypharmacy for Treatment of Diabetes and Obesity
Tschöp, Matthias H., Finan, Brian, Clemmensen, Christoffer, Gelfanov, Vasily, Perez-Tilve, Diego, Müller, Timo D., DiMarchi, Richard D.
Published in Cell metabolism (12.07.2016)
Published in Cell metabolism (12.07.2016)
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Glucagon Regulation of Energy Expenditure
Kleinert, Maximilian, Sachs, Stephan, Habegger, Kirk M, Hofmann, Susanna M, Müller, Timo D
Published in International journal of molecular sciences (30.10.2019)
Published in International journal of molecular sciences (30.10.2019)
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Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
Niu, Lili, Geyer, Philipp E, Wewer Albrechtsen, Nicolai J, Gluud, Lise L, Santos, Alberto, Doll, Sophia, Treit, Peter V, Holst, Jens J, Knop, Filip K, Vilsbøll, Tina, Junker, Anders, Sachs, Stephan, Stemmer, Kerstin, Müller, Timo D, Tschöp, Matthias H, Hofmann, Susanna M, Mann, Matthias
Published in Molecular systems biology (01.03.2019)
Published in Molecular systems biology (01.03.2019)
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Reappraisal of GIP Pharmacology for Metabolic Diseases
Finan, Brian, Müller, Timo D, Clemmensen, Christoffer, Perez-Tilve, Diego, DiMarchi, Richard D, Tschöp, Matthias H
Published in Trends in molecular medicine (01.05.2016)
Published in Trends in molecular medicine (01.05.2016)
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Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency
Sundaram, Sivaraj M, Arrulo Pereira, Adriana, Müller-Fielitz, Helge, Köpke, Hannes, De Angelis, Meri, Müller, Timo D, Heuer, Heike, Körbelin, Jakob, Krohn, Markus, Mittag, Jens, Nogueiras, Ruben, Prevot, Vincent, Schwaninger, Markus
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Recent Advances in Incretin-Based Pharmacotherapies for the Treatment of Obesity and Diabetes
Tan, Qiming, Akindehin, Seun E, Orsso, Camila E, Waldner, Richelle C, DiMarchi, Richard D, Müller, Timo D, Haqq, Andrea M
Published in Frontiers in endocrinology (Lausanne) (01.03.2022)
Published in Frontiers in endocrinology (Lausanne) (01.03.2022)
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Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo
Kulaj, Konxhe, Harger, Alexandra, Bauer, Michaela, Caliskan, Özüm S., Gupta, Tilak Kumar, Chiang, Dapi Menglin, Milbank, Edward, Reber, Josefine, Karlas, Angelos, Kotzbeck, Petra, Sailer, David N., Volta, Francesco, Lutter, Dominik, Prakash, Sneha, Merl-Pham, Juliane, Ntziachristos, Vasilis, Hauner, Hans, Pfaffl, Michael W., Tschöp, Matthias H., Müller, Timo D., Hauck, Stefanie M., Engel, Benjamin D., Gerdes, Jantje M., Pfluger, Paul T., Krahmer, Natalie, Stemmer, Kerstin
Published in Nature communications (09.02.2023)
Published in Nature communications (09.02.2023)
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Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis
Yu, Qiang, Gamayun, Igor, Wartenberg, Philipp, Zhang, Qian, Qiao, Sen, Kusumakshi, Soumya, Candlish, Sarah, Götz, Viktoria, Wen, Shuping, Das, Debajyoti, Wyatt, Amanda, Wahl, Vanessa, Ectors, Fabien, Kattler, Kathrin, Yildiz, Daniela, Prevot, Vincent, Schwaninger, Markus, Ternier, Gaetan, Giacobini, Paolo, Ciofi, Philippe, Müller, Timo D., Boehm, Ulrich
Published in Nature communications (22.03.2023)
Published in Nature communications (22.03.2023)
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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
Huang, Jianfeng, Linares, Juan F., Duran, Angeles, Xia, Wenmin, Saltiel, Alan R., Müller, Timo D., Diaz-Meco, Maria T., Moscat, Jorge
Published in Nature communications (17.05.2021)
Published in Nature communications (17.05.2021)
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Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists
Novikoff, Aaron, O'Brien, Shannon L., Bernecker, Miriam, Grandl, Gerald, Kleinert, Maximilian, Knerr, Patrick J., Stemmer, Kerstin, Klingenspor, Martin, Zeigerer, Anja, DiMarchi, Richard, Tschöp, Matthias H., Finan, Brian, Calebiro, Davide, Müller, Timo D.
Published in Molecular metabolism (Germany) (01.07.2021)
Published in Molecular metabolism (Germany) (01.07.2021)
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Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition
Mueller, Kristina M, Hartmann, Kerstin, Kaltenecker, Doris, Vettorazzi, Sabine, Bauer, Mandy, Mauser, Lea, Amann, Sabine, Jall, Sigrid, Fischer, Katrin, Esterbauer, Harald, Müller, Timo D, Tschöp, Matthias H, Magnes, Christoph, Haybaeck, Johannes, Scherer, Thomas, Bordag, Natalie, Tuckermann, Jan P, Moriggl, Richard
Published in Diabetes (New York, N.Y.) (01.02.2017)
Published in Diabetes (New York, N.Y.) (01.02.2017)
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Targeted pharmacological therapy restores β-cell function for diabetes remission
Sachs, Stephan, Bastidas-Ponce, Aimée, Tritschler, Sophie, Bakhti, Mostafa, Böttcher, Anika, Sánchez-Garrido, Miguel A, Tarquis-Medina, Marta, Kleinert, Maximilian, Fischer, Katrin, Jall, Sigrid, Harger, Alexandra, Bader, Erik, Roscioni, Sara, Ussar, Siegfried, Feuchtinger, Annette, Yesildag, Burcak, Neelakandhan, Aparna, Jensen, Christine B, Cornu, Marion, Yang, Bin, Finan, Brian, DiMarchi, Richard D, Tschöp, Matthias H, Theis, Fabian J, Hofmann, Susanna M, Müller, Timo D, Lickert, Heiko
Published in Nature metabolism (01.02.2020)
Published in Nature metabolism (01.02.2020)
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Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice
Jall, Sigrid, Sachs, Stephan, Clemmensen, Christoffer, Finan, Brian, Neff, Frauke, DiMarchi, Richard D, Tschöp, Matthias H, Müller, Timo D, Hofmann, Susanna M
Published in Molecular metabolism (Germany) (01.05.2017)
Published in Molecular metabolism (Germany) (01.05.2017)
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Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy
Sánchez-Garrido, Miguel A., Serrano-López, Víctor, Ruiz-Pino, Francisco, Vázquez, María Jesús, Rodríguez-Martín, Andrea, Torres, Encarnación, Velasco, Inmaculada, Rodríguez, Ana Belén, Chicano-Gálvez, Eduardo, Mora-Ortiz, Marina, Ohlsson, Claes, Poutanen, Matti, Pinilla, Leonor, Gaytán, Francisco, Douros, Jonathan D., Yang, Bin, Müller, Timo D., DiMarchi, Richard D., Tschöp, Matthias H., Finan, Brian, Tena-Sempere, Manuel
Published in Nature communications (01.10.2024)
Published in Nature communications (01.10.2024)
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Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
Clemmensen, Christoffer, Jall, Sigrid, Kleinert, Maximilian, Quarta, Carmelo, Gruber, Tim, Reber, Josefine, Sachs, Stephan, Fischer, Katrin, Feuchtinger, Annette, Karlas, Angelos, Simonds, Stephanie E., Grandl, Gerald, Loher, Daniela, Sanchez-Quant, Eva, Keipert, Susanne, Jastroch, Martin, Hofmann, Susanna M., Nascimento, Emmani B. M., Schrauwen, Patrick, Ntziachristos, Vasilis, Cowley, Michael A., Finan, Brian, Müller, Timo D., Tschöp, Matthias H.
Published in Nature communications (23.10.2018)
Published in Nature communications (23.10.2018)
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