Anti-obesity drug discovery: advances and challenges
Müller, Timo D., Blüher, Matthias, Tschöp, Matthias H., DiMarchi, Richard D.
Published in Nature reviews. Drug discovery (01.03.2022)
Published in Nature reviews. Drug discovery (01.03.2022)
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Journal Article
Unimolecular Polypharmacy for Treatment of Diabetes and Obesity
Tschöp, Matthias H., Finan, Brian, Clemmensen, Christoffer, Gelfanov, Vasily, Perez-Tilve, Diego, Müller, Timo D., DiMarchi, Richard D.
Published in Cell metabolism (12.07.2016)
Published in Cell metabolism (12.07.2016)
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Journal Article
Gut-Brain Cross-Talk in Metabolic Control
Clemmensen, Christoffer, Müller, Timo D., Woods, Stephen C., Berthoud, Hans-Rudolf, Seeley, Randy J., Tschöp, Matthias H.
Published in Cell (23.02.2017)
Published in Cell (23.02.2017)
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Journal Article
Glucagon Regulation of Energy Expenditure
Kleinert, Maximilian, Sachs, Stephan, Habegger, Kirk M, Hofmann, Susanna M, Müller, Timo D
Published in International journal of molecular sciences (30.10.2019)
Published in International journal of molecular sciences (30.10.2019)
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Journal Article
Ghrelin regulation of glucose metabolism
Poher, Anne-Laure, Tschöp, Matthias H., Müller, Timo D.
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
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Journal Article
Animal models of obesity and diabetes mellitus
Kleinert, Maximilian, Clemmensen, Christoffer, Hofmann, Susanna M., Moore, Mary C., Renner, Simone, Woods, Stephen C., Huypens, Peter, Beckers, Johannes, de Angelis, Martin Hrabe, Schürmann, Annette, Bakhti, Mostafa, Klingenspor, Martin, Heiman, Mark, Cherrington, Alan D., Ristow, Michael, Lickert, Heiko, Wolf, Eckhard, Havel, Peter J., Müller, Timo D., Tschöp, Matthias H.
Published in Nature reviews. Endocrinology (01.03.2018)
Published in Nature reviews. Endocrinology (01.03.2018)
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Journal Article
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency
Sundaram, Sivaraj M, Arrulo Pereira, Adriana, Müller-Fielitz, Helge, Köpke, Hannes, De Angelis, Meri, Müller, Timo D, Heuer, Heike, Körbelin, Jakob, Krohn, Markus, Mittag, Jens, Nogueiras, Ruben, Prevot, Vincent, Schwaninger, Markus
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Journal Article
Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
Niu, Lili, Geyer, Philipp E, Wewer Albrechtsen, Nicolai J, Gluud, Lise L, Santos, Alberto, Doll, Sophia, Treit, Peter V, Holst, Jens J, Knop, Filip K, Vilsbøll, Tina, Junker, Anders, Sachs, Stephan, Stemmer, Kerstin, Müller, Timo D, Tschöp, Matthias H, Hofmann, Susanna M, Mann, Matthias
Published in Molecular systems biology (01.03.2019)
Published in Molecular systems biology (01.03.2019)
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Journal Article
Gut hormone polyagonists for the treatment of type 2 diabetes
Brandt, Sara J., Götz, Anna, Tschöp, Matthias H., Müller, Timo D.
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
Published in Peptides (New York, N.Y. : 1980) (01.02.2018)
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Journal Article
Reappraisal of GIP Pharmacology for Metabolic Diseases
Finan, Brian, Müller, Timo D, Clemmensen, Christoffer, Perez-Tilve, Diego, DiMarchi, Richard D, Tschöp, Matthias H
Published in Trends in molecular medicine (01.05.2016)
Published in Trends in molecular medicine (01.05.2016)
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Journal Article
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease
Finan, Brian, Clemmensen, Christoffer, Zhu, Zhimeng, Stemmer, Kerstin, Gauthier, Karine, Müller, Luisa, De Angelis, Meri, Moreth, Kristin, Neff, Frauke, Perez-Tilve, Diego, Fischer, Katrin, Lutter, Dominik, Sánchez-Garrido, Miguel A., Liu, Peng, Tuckermann, Jan, Malehmir, Mohsen, Healy, Marc E., Weber, Achim, Heikenwalder, Mathias, Jastroch, Martin, Kleinert, Maximilian, Jall, Sigrid, Brandt, Sara, Flamant, Frédéric, Schramm, Karl-Werner, Biebermann, Heike, Döring, Yvonne, Weber, Christian, Habegger, Kirk M., Keuper, Michaela, Gelfanov, Vasily, Liu, Fa, Köhrle, Josef, Rozman, Jan, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Hofmann, Susanna M., Yang, Bin, Tschöp, Matthias H., DiMarchi, Richard, Müller, Timo D.
Published in Cell (20.10.2016)
Published in Cell (20.10.2016)
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Journal Article
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling
Zhang, Qian, Delessa, Challa Tenagne, Augustin, Robert, Bakhti, Mostafa, Colldén, Gustav, Drucker, Daniel J., Feuchtinger, Annette, Caceres, Cristina Garcia, Grandl, Gerald, Harger, Alexandra, Herzig, Stephan, Hofmann, Susanna, Holleman, Cassie Lynn, Jastroch, Martin, Keipert, Susanne, Kleinert, Maximilian, Knerr, Patrick J., Kulaj, Konxhe, Legutko, Beata, Lickert, Heiko, Liu, Xue, Luippold, Gerd, Lutter, Dominik, Malogajski, Emilija, Medina, Marta Tarquis, Mowery, Stephanie A., Blutke, Andreas, Perez-Tilve, Diego, Salinno, Ciro, Sehrer, Laura, DiMarchi, Richard D., Tschöp, Matthias H., Stemmer, Kerstin, Finan, Brian, Wolfrum, Christian, Müller, Timo D.
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
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Journal Article