Mutant ATRX: uncovering a new therapeutic target for glioma
Haase, Santiago, Garcia-Fabiani, María Belén, Carney, Stephen, Altshuler, David, Núñez, Felipe J, Méndez, Flor M, Núñez, Fernando, Lowenstein, Pedro R, Castro, Maria G
Published in Expert opinion on therapeutic targets (03.07.2018)
Published in Expert opinion on therapeutic targets (03.07.2018)
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Journal Article
Epigenetic reprogramming and chromatin accessibility in pediatric diffuse intrinsic pontine gliomas: a neural developmental disease
Mendez, Flor M, Núñez, Felipe J, Garcia-Fabiani, Maria B, Haase, Santiago, Carney, Stephen, Gauss, Jessica C, Becher, Oren J, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (20.02.2020)
Published in Neuro-oncology (Charlottesville, Va.) (20.02.2020)
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Journal Article
Genetically Engineered Mouse Model of Brainstem High-Grade Glioma
Nunez, Fernando M., Gauss, Jessica C., Mendez, Flor M., Haase, Santiago, Lowenstein, Pedro R., Castro, Maria G.
Published in STAR protocols (18.12.2020)
Published in STAR protocols (18.12.2020)
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Journal Article
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
Zhang, Yaqing, Velez-Delgado, Ashley, Mathew, Esha, Li, Dongjun, Mendez, Flor M, Flannagan, Kevin, Rhim, Andrew D, Simeone, Diane M, Beatty, Gregory L, Pasca di Magliano, Marina
Published in Gut (01.01.2017)
Published in Gut (01.01.2017)
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Journal Article
Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
Mendez, Flor M, Núñez, Felipe J, Zorrilla-Veloz, Rocío I, Lowenstein, Pedro R, Castro, Maria G
Published in Journal of visualized experiments (29.01.2018)
Published in Journal of visualized experiments (29.01.2018)
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Journal Article
Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Núñez, Felipe J, Mendez, Flor M, Garcia-Fabiani, Maria B, Pardo, Joaquín, Edwards, Marta, Lowenstein, Pedro R, Castro, Maria G
Published in Journal of visualized experiments (09.01.2019)
Published in Journal of visualized experiments (09.01.2019)
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Journal Article
Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma
Mendez, Flor, Kadiyala, Padma, Nunez, Felipe J, Carney, Stephen, Nunez, Fernando M, Gauss, Jessica C, Ravindran, Ramya, Pawar, Sheeba, Edwards, Marta, Garcia-Fabiani, Maria Belen, Haase, Santiago, Lowenstein, Pedro R, Castro, Maria G
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
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Journal Article
Abstract 5101: Characterization of a mouse model using the Sleeping Beauty transposon method to study diffuse intrinsic pontine glioma (DIPG)
Ravindran, Ramya, Mendez, Flor M., Nunez, Felipe J., Koschmann, Carl, Dzaman, Marta, Pawar, Sheeba, Lowenstein, Pedro R., Castro, Maria G.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 3033: Generation of a mouse model of young adult glioblatoma: In vivo expression of mutated IDH1-R132H gene using the sleeping beauty transposase system
Nunez, Felipe J., Mendez, Flor M., Koschmann, Carl, Calinescu, Alexandra, Lowenstein, Pedro R., Castro, Maria G.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Núñez, Felipe J., Mendez, Flor M., Garcia-Fabiani, Maria B., Pardo, Joaquín, Edwards, Marta, Lowenstein, Pedro R., Castro, Maria G.
Published in Journal of visualized experiments (09.01.2019)
Published in Journal of visualized experiments (09.01.2019)
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Journal Article
GENE-17. GENERATION OF A MOUSE MODEL OF DIFFUSE INTRINSIC PONTINE GLIOMA HARBORING ACVR1 G328V AND H3.1 K27M MUTATIONS
Mendez, Flor M, Nunez, Felipe J, Koschmann, Carl, Saxena, Meghna, Kamran, Neha, Dzaman, Marta, Pawar, Sheeba, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2017)
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Journal Article
Abstract IA21: Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immune-suppressive environment in pancreatic cancer
Zhang, Yaqing, Mathew, Esha, Velez-Delgado, Ashley, Long, Kristen B., Li, Dongjun, Mendez, Flor M., Flannagan, Kevin, Rhim, Andrew D., Simeone, Diane M., Beatty, Gregory L., Magliano, Marina Pasca di
Published in Cancer research (Chicago, Ill.) (15.12.2016)
Published in Cancer research (Chicago, Ill.) (15.12.2016)
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Journal Article
TMOD-11. USING THE SLEEPING BEAUTY TRANSPOSASE SYSTEM TO GENERATE MOUSE MODELS OF DIFFUSE INTRINSIC PONTINE GLIOMA HARBORING ACVR1 AND H3K27M MUTATIONS
Mendez, Flor M, Nunez, Felipe J, Koschmann, Carl, Calinescu, Alexandra, Saxena, Meghna, Kamran, Neha, Pawar, Sheeba, Dzaman, Marta, Lowenstein, Pedro R, Castro, Maria G.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
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Journal Article
HG-03A NOVEL MOUSE MODEL OF YOUNG ADULT GLIOBLASTOMA: IN VIVO EXPRESSION OF MUTATED IDH1 (R132H) GENE USING THE SLEEPING BEAUTY TRANSPOSASE SYSTEM
Nunez, Felipe J., Mendez, Flor M., Koschmann, Carl, Calinescu, Alexandra, Dzaman, Marta, Lowenstein, Pedro R., Castro, Maria G.
Published in Neuro-oncology (Charlottesville, Va.) (21.04.2015)
Published in Neuro-oncology (Charlottesville, Va.) (21.04.2015)
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Journal Article
GENT-06. IN VIVO EXPRESSION OF MUTATED IDH1 (R132H) GENE IN A MOUSE MODEL OF YOUNG ADULT GLIOBLASTOMA HAS IMPACT IN MEDIAN SURVIVAL, DNA-REPAIR PATHWAYS, AUTOPHAGY AND OLIGODENDROCYTE DIFFERENTIATION
Nunez, Felipe J, Mendez, Flor M, Koschmann, Carl, Calinescu, Alexandra, Saxena, Meghna, Kadiyala, Padma, Savelieff, Marsha, Patel, Rohin, Manawar, Shaan, Venneti, Sriram, Dzaman, Marta, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
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Journal Article
GENE-58. EPIGENETIC REPROGRAMMING IN MUTANT IDH1 GLIOMA IMPACTS MEDIAN SURVIVAL, ENHANCES DNA DAMAGE RESPONSE AND CONFERS RADIO-RESISTANCE
Nunez, Felipe J, Mendez, Flor M, Kadiyala, Padma, Savelieff, Masha, Koschmann, Carl, Carney, Stephen, Patel, Rohin, Manawar, Shaan, Kamran, Neha, Saxena, Meghna, Ljungman, Mats, Qin, Tingting, Maureen, Sator, Dzaman, Marta, Vennneti, Sriram, Hervey-Jumper, Shawn, Figueroa, Maria E, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
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Journal Article
GENE-17. GENERATION OF A MOUSE MODEL OF DIFFUSE INTRINSIC PONTINE GLIOMA HARBORING ACVR1 G328V AND H3.1 K27M MUTATIONS
Mendez, Flor M, Nunez, Felipe J, Koschmann, Carl, Saxena, Meghna, Kamran, Neha, Dzaman, Marta, Pawar, Sheeba, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
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Journal Article
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas
Garcia-Fabiani, Maria B, Haase, Santiago, Banerjee, Kaushik, McClellan, Brandon, Zhu, Ziwen, Mujeeb, Anzar, Li, Yingxiang, Yu, Jin, Kadiyala, Padma, Taher, Ayman, Núñez, Felipe J, Alghamri, Mahmoud S, Comba, Andrea, Mendez, Flor M, Nicola Candia, Alejandro J, Salazar, Brittany, Koschmann, Carl, Nunez, Fernando M, Edwards, Marta, Qin, Tingting, Sartor, Maureen A, Lowenstein, Pedro R, Castro, Maria G
Published in bioRxiv (13.06.2023)
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Published in bioRxiv (13.06.2023)
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