A prolyl oligopeptidase inhibitor, KYP‐2047, reduces α‐synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease
Myöhänen, TT, Hannula, MJ, Van Elzen, R, Gerard, M, Van Der Veken, P, García‐Horsman, JA, Baekelandt, V, Männistö, PT, Lambeir, AM
Published in British journal of pharmacology (01.06.2012)
Published in British journal of pharmacology (01.06.2012)
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Prolyl oligopeptidase colocalizes with α-synuclein, β-amyloid, tau protein and astroglia in the post-mortem brain samples with Parkinson’s and Alzheimer’s diseases
Hannula, M.J, Myöhänen, T.T, Tenorio-Laranga, J, Männistö, P.T, Garcia-Horsman, J.A
Published in Neuroscience (09.07.2013)
Published in Neuroscience (09.07.2013)
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Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner
Myöhänen, TT, Tenorio‐Laranga, J, Jokinen, B, Vázquez‐Sánchez, R, Moreno‐Baylach, MJ, García‐Horsman, JA, Männistö, PT
Published in British journal of pharmacology (01.08.2011)
Published in British journal of pharmacology (01.08.2011)
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Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis
Boku, S, Izumi, T, Abe, S, Takahashi, T, Nishi, A, Nomaru, H, Naka, Y, Kang, G, Nagashima, M, Hishimoto, A, Enomoto, S, Duran-Torres, G, Tanigaki, K, Zhang, J, Ye, K, Kato, S, Männistö, P T, Kobayashi, K, Hiroi, N
Published in Molecular psychiatry (01.04.2018)
Published in Molecular psychiatry (01.04.2018)
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On the role of prolyl oligopeptidase in health and disease
Garcia-Horsman, JA, Maennistoe, P T, Venaelaeinen, JI
Published in Neuropeptides (Edinburgh) (01.02.2007)
Published in Neuropeptides (Edinburgh) (01.02.2007)
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Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A
Rauhavirta, T, Qiao, S.-W, Jiang, Z, Myrsky, E, Loponen, J, Korponay-Szabó, I.R, Salovaara, H, Garcia-Horsman, J.A, Venäläinen, J, Männistö, P.T, Collighan, R, Mongeot, A, Griffin, M, Mäki, M, Kaukinen, K, Lindfors, K
Published in Clinical and experimental immunology (01.04.2011)
Published in Clinical and experimental immunology (01.04.2011)
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Inhibitors of catechol‐O‐methyltransferase sensitize mice to pain
Kambur, O, Talka, R, Ansah, OB, Kontinen, VK, Pertovaara, A, Kalso, E, Männistö, PT
Published in British journal of pharmacology (01.12.2010)
Published in British journal of pharmacology (01.12.2010)
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Vascular endothelial growth factor C acts as a neurotrophic factor for dopamine neurons in vitro and in vivo
Piltonen, M, Planken, A, Leskelä, O, Myöhänen, T.T, Hänninen, A.-L, Auvinen, P, Alitalo, K, Andressoo, J.-O, Saarma, M, Männistö, P.T
Published in Neuroscience (29.09.2011)
Published in Neuroscience (29.09.2011)
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Degradation of coeliac disease-inducing rye secalin by germinating cereal enzymes: diminishing toxic effects in intestinal epithelial cells
Stenman, S.M, Lindfors, K, Venäläinen, J.I, Hautala, A, Männistö, P.T, Garcia-Horsman, J.A, Kaukovirta-Norja, A, Auriola, S, Mauriala, T, Mäki, M, Kaukinen, K
Published in Clinical and experimental immunology (01.08.2010)
Published in Clinical and experimental immunology (01.08.2010)
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Comparison of motor performance, brain biochemistry and histology of two A30P α-synuclein transgenic mouse strains
Piltonen, M, Savolainen, M, Patrikainen, S, Baekelandt, V, Myöhänen, T.T, Männistö, P.T
Published in Neuroscience (12.02.2013)
Published in Neuroscience (12.02.2013)
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Importance of membrane‐bound catechol‐O‐methyltransferase in L‐DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice
Käenmäki, M, Tammimäki, A, Garcia‐Horsman, JA, Myöhänen, T, Schendzielorz, N, Karayiorgou, M, Gogos, JA, Männistö, PT
Published in British journal of pharmacology (01.12.2009)
Published in British journal of pharmacology (01.12.2009)
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Spatial association of prolyl oligopeptidase, inositol 1,4,5-triphosphate type 1 receptor, substance P and its neurokinin-1 receptor in the rat brain: An immunohistochemical colocalization study
Myohanen, T T, Venalainen, JI, Garcia-Horsman, JA, Mannisto, P T
Published in Neuroscience (02.06.2008)
Published in Neuroscience (02.06.2008)
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Effects of aqueous extracts of Halimeda incrassata (Ellis) Lamouroux and Bryothamnion triquetrum (S.G.Gmelim) Howe on hydrogen peroxide and methyl mercury-induced oxidative stress in GT1-7 mouse hypothalamic immortalized cells
Fallarero, A., Loikkanen, J.J., Männistö, P.T., Castañeda, O., Vidal, A.
Published in Phytomedicine (Stuttgart) (2003)
Published in Phytomedicine (Stuttgart) (2003)
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Molecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity
Kaszuba, K., Róg, T., St. Pierre, J.-F., Männistö, P.T., Karttunen, M., Bunker, A.
Published in SAR and QSAR in environmental research (01.10.2009)
Published in SAR and QSAR in environmental research (01.10.2009)
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Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task
KOSKINEN, T, RUOTSALAINEN, S, PUUMALA, T, LAPPALAINEN, R, KOIVISTO, E, MÄNNISTÖ, P. T, SIRVIÖ, J
Published in Neuropharmacology (28.01.2000)
Published in Neuropharmacology (28.01.2000)
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Elimination of extracellular dopamine in the medial prefrontal cortex of conscious mice analysed using selective enzyme and uptake inhibitors
Tammimaki, A, Aonurm-Helm, A, Kaenmaki, M, Mannisto, P T
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01.04.2016)
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Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01.04.2016)
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