Identification of suitable reference genes for normalization of reverse transcription quantitative real-time PCR (RT-qPCR) in the fibrotic phase of the bleomycin mouse model of pulmonary fibrosis
Norman, Oula, Koivunen, Jarkko, Mäki, Joni M, Pihlajaniemi, Taina, Heikkinen, Anne
Published in PloS one (17.10.2022)
Published in PloS one (17.10.2022)
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Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
Rachman-Tzemah, Chen, Zaffryar-Eilot, Shelly, Grossman, Moran, Ribero, Dario, Timaner, Michael, Mäki, Joni M., Myllyharju, Johanna, Bertolini, Francesco, Hershkovitz, Dov, Sagi, Irit, Hasson, Peleg, Shaked, Yuval
Published in Cell reports (Cambridge) (25.04.2017)
Published in Cell reports (Cambridge) (25.04.2017)
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Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
Rosendahl, Ann-Helen, Monnius, Mia, Laitala, Anu, Railo, Antti, Miinalainen, Ilkka, Heljasvaara, Ritva, Mäki, Joni M., Myllyharju, Johanna
Published in The Journal of biological chemistry (01.04.2022)
Published in The Journal of biological chemistry (01.04.2022)
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Muscle composition is regulated by a Lox-TGFβ feedback loop
Kutchuk, Liora, Laitala, Anu, Soueid-Bomgarten, Sharon, Shentzer, Pessia, Rosendahl, Ann-Helen, Eilot, Shelly, Grossman, Moran, Sagi, Irit, Sormunen, Raija, Myllyharju, Johanna, Mäki, Joni M, Hasson, Peleg
Published in Development (Cambridge) (01.03.2015)
Published in Development (Cambridge) (01.03.2015)
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Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism
Tapio, Joona, Halmetoja, Riikka, Dimova, Elitsa Y., Mäki, Joni M., Laitala, Anu, Walkinshaw, Gail, Myllyharju, Johanna, Serpi, Raisa, Koivunen, Peppi
Published in The Journal of biological chemistry (01.08.2022)
Published in The Journal of biological chemistry (01.08.2022)
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Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways
Ullah, Karim, Rosendahl, Ann-Helen, Izzi, Valerio, Bergmann, Ulrich, Pihlajaniemi, Taina, Mäki, Joni M, Myllyharju, Johanna
Published in Scientific reports (08.12.2017)
Published in Scientific reports (08.12.2017)
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Journal Article
Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium
Dengler, Franziska, Sova, Sofia, Salo, Antti M, Mäki, Joni M, Koivunen, Peppi, Myllyharju, Johanna
Published in International journal of molecular sciences (14.04.2021)
Published in International journal of molecular sciences (14.04.2021)
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Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families
Aviram, Rohtem, Zaffryar-Eilot, Shelly, Hubmacher, Dirk, Grunwald, Hagar, Mäki, Joni M., Myllyharju, Johanna, Apte, Suneel S., Hasson, Peleg
Published in Matrix biology (01.01.2019)
Published in Matrix biology (01.01.2019)
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PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis
Elamaa, Harri, Kaakinen, Mika, Nätynki, Marjut, Szabo, Zoltan, Ronkainen, Veli-Pekka, Äijälä, Ville, Mäki, Joni M., Kerkelä, Risto, Myllyharju, Johanna, Eklund, Lauri
Published in Angiogenesis (London) (01.05.2022)
Published in Angiogenesis (London) (01.05.2022)
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Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury
Hyvärinen, Jaana, Hassinen, Ilmo E., Sormunen, Raija, Mäki, Joni M., Kivirikko, Kari I., Koivunen, Peppi, Myllyharju, Johanna
Published in The Journal of biological chemistry (30.04.2010)
Published in The Journal of biological chemistry (30.04.2010)
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Journal Article
Lysyl Oxidase Is Essential for Normal Development and Function of the Respiratory System and for the Integrity of Elastic and Collagen Fibers in Various Tissues
Mäki, Joni M., Sormunen, Raija, Lippo, Sari, Kaarteenaho-Wiik, Riitta, Soininen, Raija, Myllyharju, Johanna
Published in The American journal of pathology (01.10.2005)
Published in The American journal of pathology (01.10.2005)
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Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis
Laitala, Anu, Aro, Ellinoora, Walkinshaw, Gail, Mäki, Joni M., Rossi, Maarit, Heikkilä, Minna, Savolainen, Eeva-Riitta, Arend, Michael, Kivirikko, Kari I., Koivunen, Peppi, Myllyharju, Johanna
Published in Blood (18.10.2012)
Published in Blood (18.10.2012)
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Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice
MÄKI, Joni M, RÄSÄNEN, Juha, TIKKANEN, Hilkka, SORMUNEN, Raija, MÄKIKALLIO, Kaarin, KIVIRIKKO, Kari I, SOININEN, Raija
Published in Circulation (New York, N.Y.) (05.11.2002)
Published in Circulation (New York, N.Y.) (05.11.2002)
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Contribution of collagen XIII to lung function and development of pulmonary fibrosis
Norman, Oula, Koivunen, Jarkko, Kaarteenaho, Riitta, Salo, Antti M, Mäki, Joni M, Myllyharju, Johanna, Pihlajaniemi, Taina, Heikkinen, Anne
Published in BMJ open respiratory research (12.12.2023)
Published in BMJ open respiratory research (12.12.2023)
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The Ras Signaling Inhibitor LOX-PP Interacts with Hsp70 and c-Raf To Reduce Erk Activation and Transformed Phenotype of Breast Cancer Cells
Sato, Seiichi, Trackman, Philip C., Mäki, Joni M., Myllyharju, Johanna, Kirsch, Kathrin H., Sonenshein, Gail E.
Published in Molecular and Cellular Biology (01.07.2011)
Published in Molecular and Cellular Biology (01.07.2011)
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Lysyl Oxidase Oxidizes Cell Membrane Proteins and Enhances the Chemotactic Response of Vascular Smooth Muscle Cells
Lucero, Héctor A., Ravid, Katya, Grimsby, Jessica L., Rich, Celeste B., DiCamillo, Sandra J., Mäki, Joni M., Myllyharju, Johanna, Kagan, Herbert M.
Published in The Journal of biological chemistry (29.08.2008)
Published in The Journal of biological chemistry (29.08.2008)
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LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer
GUOJUN WU, ZHONGMIN GUO, SIDRANSKY, David, XIAOFEI CHANG, MYOUNG SOOK KIM, NAGPAL, Jatin K, JUNWEI LIU, MAKI, Joni M, KIVIRIKKO, Kari I, ETHIER, Stephen P, TRINK, Barry
Published in Cancer research (Chicago, Ill.) (01.05.2007)
Published in Cancer research (Chicago, Ill.) (01.05.2007)
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Journal Article
Identification of suitable reference genes for normalization of reverse transcription quantitative real-time PCR
Norman, Oula, Koivunen, Jarkko, Mäki, Joni M, Pihlajaniemi, Taina, Heikkinen, Anne
Published in PloS one (17.10.2022)
Published in PloS one (17.10.2022)
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Journal Article