The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter
Plenge, Per, Abramyan, Ara M., Sørensen, Gunnar, Mørk, Arne, Weikop, Pia, Gether, Ulrik, Bang-Andersen, Benny, Shi, Lei, Loland, Claus J.
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Published in Nature communications (20.03.2020)
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Discovery of 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A Novel Multimodal Compound for the Treatment of Major Depressive Disorder
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Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator
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Published in The Journal of pharmacology and experimental therapeutics (01.09.2014)
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Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats
Mørk, Arne, Montezinho, Liliana P., Miller, Silke, Trippodi-Murphy, Crista, Plath, Niels, Li, Yan, Gulinello, Maria, Sanchez, Connie
Published in Pharmacology, biochemistry and behavior (01.04.2013)
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Effects of the 5-HT6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex
Mørk, Arne, Russell, Rasmus Vinther, de Jong, Inge E.M., Smagin, Gennady
Published in European journal of pharmacology (15.03.2017)
Published in European journal of pharmacology (15.03.2017)
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The 5-HT6 receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus
Herrik, Kjartan F., Mørk, Arne, Richard, Nelly, Bundgaard, Christoffer, Bastlund, Jesper F., de Jong, Inge E.M.
Published in Neuropharmacology (01.08.2016)
Published in Neuropharmacology (01.08.2016)
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Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration
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Published in Brain research (16.01.2014)
Published in Brain research (16.01.2014)
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A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors
Jeon, Jongrye, Dencker, Ditte, Wortwein, Gitta, Woldbye, David P. D, Cui, Yinghong, Davis, Albert A, Levey, Allan I, Schutz, Gunther, Sager, Thomas N, Mork, Arne, Li, Cuiling, Deng, Chu-Xia, Fink-Jensen, Anders, Wess, Jurgen
Published in The Journal of neuroscience (10.02.2010)
Published in The Journal of neuroscience (10.02.2010)
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Combined In Vivo Microdialysis and PET Studies to Validate [ 11 C]Yohimbine Binding as a Marker of Noradrenaline Release
Landau, Anne Marlene, Jakobsen, Steen, Thomsen, Majken Borup, Alstrup, Aage Kristian Olsen, Orlowski, Dariusz, Jacobsen, Jan, Wegener, Gregers, Mørk, Arne, Sørensen, Jens Christian Hedemann, Doudet, Doris J
Published in Biomolecules (Basel, Switzerland) (14.04.2023)
Published in Biomolecules (Basel, Switzerland) (14.04.2023)
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A Subpopulation of Neuronal M 4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors
Jeon, Jongrye, Dencker, Ditte, Wörtwein, Gitta, Woldbye, David P. D., Cui, Yinghong, Davis, Albert A., Levey, Allan I., Schütz, Günther, Sager, Thomas N., Mørk, Arne, Li, Cuiling, Deng, Chu-Xia, Fink-Jensen, Anders, Wess, Jürgen
Published in The Journal of neuroscience (10.02.2010)
Published in The Journal of neuroscience (10.02.2010)
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A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission
Nielsen, Jacob, Fejgin, Kim, Sotty, Florence, Nielsen, Vibeke, Mørk, Arne, Christoffersen, Claus T., Yavich, Leonid, Lauridsen, Jes B., Clausen, Dorte, Larsen, Peter H., Egebjerg, Jan, Werge, Thomas M., Kallunki, Pekka, Christensen, Kenneth V., Didriksen, Michael
Published in Translational psychiatry (30.11.2017)
Published in Translational psychiatry (30.11.2017)
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The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice
Qvist, Per, Christensen, Jane Hvarregaard, Vardya, Irina, Rajkumar, Anto Praveen, Mørk, Arne, Paternoster, Veerle, Füchtbauer, Ernst-Martin, Pallesen, Jonatan, Fryland, Tue, Dyrvig, Mads, Hauberg, Mads Engel, Lundsberg, Birgitte, Fejgin, Kim, Nyegaard, Mette, Jensen, Kimmo, Nyengaard, Jens Randel, Mors, Ole, Didriksen, Michael, Børglum, Anders Dupont
Published in Biological psychiatry (1969) (01.07.2017)
Published in Biological psychiatry (1969) (01.07.2017)
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Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice
Rajkumar, Anto P., Qvist, Per, Donskov, Julie G., Lazarus, Ross, Pallesen, Jonatan, Nava, Nicoletta, Winther, Gudrun, Liebenberg, Nico, Cour, Sanne H. la, Paternoster, Veerle, Fryland, Tue, Palmfeldt, Johan, Fejgin, Kim, Mørk, Arne, Nyegaard, Mette, Pakkenberg, Bente, Didriksen, Michael, Nyengaard, Jens R., Wegener, Gregers, Mors, Ole, Christensen, Jane H., Børglum, Anders D.
Published in Translational psychiatry (17.07.2020)
Published in Translational psychiatry (17.07.2020)
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