Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
Chuah, Marinee K L, Ma, Ling, VandenDriessche, Thierry, Manoj, Namitha, Samara-Kuko, Ermira, Grzela, Dawid P, Schmitt, Andrea, Pryputniewicz, Diana, Fletcher, Bradley, Jerchow, Boris, Mátés, Lajos, Matrai, Janka, Gysemans, Conny, Becker, Katja, Miskey, Csaba, Belay, Eyayu, Acosta-Sanchez, Abel, Ivics, Zoltán, Izsvák, Zsuzsanna
Published in Nature genetics (01.06.2009)
Published in Nature genetics (01.06.2009)
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Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering
Voigt, Franka, Wiedemann, Lisa, Zuliani, Cecilia, Querques, Irma, Sebe, Attila, Mátés, Lajos, Izsvák, Zsuzsanna, Ivics, Zoltán, Barabas, Orsolya
Published in Nature communications (30.03.2016)
Published in Nature communications (30.03.2016)
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Germline transgenic pigs by Sleeping Beauty transposition in porcine zygotes and targeted integration in the pig genome
Garrels, Wiebke, Mátés, Lajos, Holler, Stephanie, Dalda, Anna, Taylor, Ulrike, Petersen, Björn, Niemann, Heiner, Izsvák, Zsuzsanna, Ivics, Zoltán, Kues, Wilfried A
Published in PloS one (29.08.2011)
Published in PloS one (29.08.2011)
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Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons
Ivics, Zoltán, Garrels, Wiebke, Mátés, Lajos, Yau, Tien Yin, Bashir, Sanum, Zidek, Vaclav, Landa, Vladimír, Geurts, Aron, Pravenec, Michal, Rülicke, Thomas, Kues, Wilfried A, Izsvák, Zsuzsanna
Published in Nature protocols (01.04.2014)
Published in Nature protocols (01.04.2014)
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Comparative Analysis of Transposable Element Vector Systems in Human Cells
Grabundzija, Ivana, Irgang, Markus, Mátés, Lajos, Belay, Eyayu, Matrai, Janka, Gogol-Döring, Andreas, Kawakami, Koichi, Chen, Wei, Ruiz, Patricia, Chuah, Marinee K.L., VandenDriessche, Thierry, Izsvák, Zsuzsanna, Ivics, Zoltán
Published in Molecular therapy (01.06.2010)
Published in Molecular therapy (01.06.2010)
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The Ancient mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends
Miskey, Csaba, Papp, Balázs, Mátés, Lajos, Sinzelle, Ludivine, Keller, Heiko, Izsvák, Zsuzsanna, Ivics, Zoltán
Published in Molecular and Cellular Biology (01.06.2007)
Published in Molecular and Cellular Biology (01.06.2007)
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Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits
Katter, Katharina, Geurts, Aron M, Hoffmann, Orsolya, Mátés, Lajos, Landa, Vladimir, Hiripi, László, Moreno, Carol, Lazar, Jozef, Bashir, Sanum, Zidek, Vaclav, Popova, Elena, Jerchow, Boris, Becker, Katja, Devaraj, Anantharam, Walter, Ingrid, Grzybowksi, Michael, Corbett, Molly, Filho, Artur Rangel, Hodges, Matthew R, Bader, Michael, Ivics, Zoltán, Jacob, Howard J, Pravenec, Michal, Bosze, Zsuzsanna, Rülicke, Thomas, Izsvák, Zsuzsanna
Published in The FASEB journal (01.03.2013)
Published in The FASEB journal (01.03.2013)
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Stable gene transfer and expression in cord blood–derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system
Xue, Xingkui, Huang, Xin, Nodland, Sonja E., Mátés, Lajos, Ma, Linan, Izsvák, Zsuzsanna, Ivics, Zoltán, LeBien, Tucker W., McIvor, R. Scott, Wagner, John E., Zhou, Xianzheng
Published in Blood (13.08.2009)
Published in Blood (13.08.2009)
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A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver
Kopasz, Anna Georgina, Pusztai, Dávid Zsolt, Karkas, Réka, Hudoba, Liza, Abdullah, Khaldoon Sadiq Ahmed, Imre, Gergely, Pankotai-Bodó, Gabriella, Migh, Ede, Nagy, Andrea, Kriston, András, Germán, Péter, Drubi, Andrea Bakné, Molnár, Anna, Fekete, Ildikó, Dani, Virág Éva, Ocsovszki, Imre, Puskás, László Géza, Horváth, Péter, Sükösd, Farkas, Mátés, Lajos
Published in BMC biology (01.04.2022)
Published in BMC biology (01.04.2022)
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Combination of Alanine and Glutathione as Targeting Ligands of Nanoparticles Enhances Cargo Delivery into the Cells of the Neurovascular Unit
Porkoláb, Gergő, Mészáros, Mária, Tóth, András, Szecskó, Anikó, Harazin, András, Szegletes, Zsolt, Ferenc, Györgyi, Blastyák, András, Mátés, Lajos, Rákhely, Gábor, Deli, Mária A., Veszelka, Szilvia
Published in Pharmaceutics (07.07.2020)
Published in Pharmaceutics (07.07.2020)
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Comparative Genomic Integration Profiling of Sleeping Beauty Transposons Mobilized With High Efficacy From Integrase-defective Lentiviral Vectors in Primary Human Cells
Moldt, Brian, Miskey, Csaba, Staunstrup, Nicklas Heine, Gogol-Döring, Andreas, Bak, Rasmus O, Sharma, Nynne, Mátés, Lajos, Izsvák, Zsuzsanna, Chen, Wei, Ivics, Zoltán, Mikkelsen, Jacob Giehm
Published in Molecular therapy (01.08.2011)
Published in Molecular therapy (01.08.2011)
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Journal Article
Structural Determinants of Sleeping Beauty Transposase Activity
Abrusán, György, Yant, Stephen R, Szilágyi, András, Marsh, Joseph A, Mátés, Lajos, Izsvák, Zsuzsanna, Barabás, Orsolya, Ivics, Zoltán
Published in Molecular therapy (01.08.2016)
Published in Molecular therapy (01.08.2016)
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Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration
Deák, Ferenc, Mátés, Lajos, Korpos, Eva, Zvara, Agnes, Szénási, Tibor, Kiricsi, Mónika, Mendler, Luca, Keller-Pintér, Anikó, Ozsvári, Béla, Juhász, Hajnalka, Sorokin, Lydia, Dux, László, Mermod, Nicolas, Puskás, László G, Kiss, Ibolya
Published in Journal of cell science (01.08.2014)
Published in Journal of cell science (01.08.2014)
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Novel Hyperactive Transposons for Genetic Modification of Induced Pluripotent and Adult Stem Cells: A Nonviral Paradigm for Coaxed Differentiation
Belay, Eyayu, Mátrai, Janka, Acosta‐Sanchez, Abel, Ma, Ling, Quattrocelli, Mattia, Mátés, Lajos, Sancho‐Bru, Pau, Geraerts, Martine, Yan, Bing, Vermeesch, Joris, Rincón, Melvin Yesid, Samara‐Kuko, Ermira, Ivics, Zoltán, Verfaillie, Catherine, Sampaolesi, Maurilio, Izsvák, Zsuzsanna, VandenDriessche, Thierry, Chuah, Marinee K. L.
Published in Stem cells (Dayton, Ohio) (01.10.2010)
Published in Stem cells (Dayton, Ohio) (01.10.2010)
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Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis
Szénási, Tibor, Kénesi, Erzsébet, Nagy, Andrea, Molnár, Annamária, Bálint, Bálint László, Zvara, Ágnes, Csabai, Zsolt, Deák, Ferenc, Boros Oláh, Beáta, Mátés, Lajos, Nagy, László, Puskás, László G., Kiss, Ibolya
Published in Biochimica et biophysica acta (01.10.2013)
Published in Biochimica et biophysica acta (01.10.2013)
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Applying a “Double‐Feature” Promoter to Identify Cardiomyocytes Differentiated from Human Embryonic Stem Cells Following Transposon‐Based Gene Delivery
Orbán, Tamás I., Apáti, Ágota, Németh, Andrea, Varga, Nóra, Krizsik, Virág, Schamberger, Anita, Szebényi, Kornélia, Erdei, Zsuzsa, Várady, György, Karászi, Éva, Homolya, László, Német, Katalin, Gócza, Elen, Miskey, Csaba, Mátés, Lajos, Ivics, Zoltán, Izsvák, Zsuzsanna, Sarkadi, Balázs
Published in Stem cells (Dayton, Ohio) (01.05.2009)
Published in Stem cells (Dayton, Ohio) (01.05.2009)
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Journal Article
Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons
Ivics, Zoltán, Mátés, Lajos, Yau, Tien Yin, Landa, Vladimír, Zidek, Vaclav, Bashir, Sanum, Hoffmann, Orsolya I, Hiripi, László, Garrels, Wiebke, Kues, Wilfried A, Bösze, Zsuzsanna, Geurts, Aron, Pravenec, Michal, Rülicke, Thomas, Izsvák, Zsuzsanna
Published in Nature protocols (01.04.2014)
Published in Nature protocols (01.04.2014)
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Journal Article
Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons
Ivics, Zoltán, Hiripi, László, Hoffmann, Orsolya I, Mátés, Lajos, Yau, Tien Yin, Bashir, Sanum, Zidek, Vaclav, Landa, Vladimír, Geurts, Aron, Pravenec, Michal, Rülicke, Thomas, Bösze, Zsuzsanna, Izsvák, Zsuzsanna
Published in Nature protocols (01.04.2014)
Published in Nature protocols (01.04.2014)
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Journal Article
Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers
Kolacsek, Orsolya, Krízsik, Virág, Schamberger, Anita, Erdei, Zsuzsa, Apáti, Agota, Várady, György, Mátés, Lajos, Izsvák, Zsuzsanna, Ivics, Zoltán, Sarkadi, Balázs, Orbán, Tamás I
Published in Mobile DNA (03.03.2011)
Published in Mobile DNA (03.03.2011)
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Transposon-mediated genome manipulation in vertebrates
Ivics, Zoltán, Li, Meng Amy, Mátés, Lajos, Boeke, Jef D, Nagy, Andras, Bradley, Allan, Izsvák, Zsuzsanna
Published in Nature methods (01.06.2009)
Published in Nature methods (01.06.2009)
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