Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium
Lyssenko, Nicholas N., Haider, Naqi, Picataggi, Antonino, Cipollari, Eleonora, Jiao, Wanzhen, Phillips, Michael C., Rader, Daniel J., Chavali, Venkata Ramana Murthy
Published in Journal of lipid research (01.10.2018)
Published in Journal of lipid research (01.10.2018)
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Journal Article
Down-Regulation of ABCA7 in Human Microglia, Astrocyte and THP-1 Cell Lines by Cholesterol Depletion, IL-1β and TNFα, or PMA
Wiener, Joel P, Desire, Sindy, Garliyev, Viktor, Lyssenko III, Nicholas, Praticò, Domenico, Lyssenko, Nicholas N
Published in Cells (Basel, Switzerland) (25.08.2023)
Published in Cells (Basel, Switzerland) (25.08.2023)
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Journal Article
Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein
Luthi, Andrea J., Lyssenko, Nicholas N., Quach, Duyen, McMahon, Kaylin M., Millar, John S., Vickers, Kasey C., Rader, Daniel J., Phillips, Michael C., Mirkin, Chad A., Thaxton, C.Shad
Published in Journal of lipid research (01.05.2015)
Published in Journal of lipid research (01.05.2015)
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Journal Article
Mechanisms Responsible for the Compositional Heterogeneity of Nascent High Density Lipoprotein
Lund-Katz, Sissel, Lyssenko, Nicholas N., Nickel, Margaret, Nguyen, David, Chetty, Palaniappan Sevugan, Weibel, Ginny, Phillips, Michael C.
Published in The Journal of biological chemistry (09.08.2013)
Published in The Journal of biological chemistry (09.08.2013)
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Journal Article
ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease
Ko, Yi-An, Billheimer, Jeffrey T, Lyssenko, Nicholas N, Kueider-Paisley, Alexandra, Wolk, David A, Arnold, Steven E, Leung, Yuk Yee, Shaw, Leslie M, Trojanowski, John Q, Kaddurah-Daouk, Rima F, Kling, Mitchel A, Rader, Daniel J
Published in Alzheimer's research & therapy (26.12.2022)
Published in Alzheimer's research & therapy (26.12.2022)
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Journal Article
Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport
Kuwano, Takashi, Bi, Xin, Cipollari, Eleonora, Yasuda, Tomoyuki, Lagor, William R., Szapary, Hannah J., Tohyama, Junichiro, Millar, John S., Billheimer, Jeffrey T., Lyssenko, Nicholas N., Rader, Daniel J.
Published in Journal of lipid research (01.04.2017)
Published in Journal of lipid research (01.04.2017)
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Journal Article
Aminophospholipid Translocase TAT-1 Promotes Phosphatidylserine Exposure during C. elegans Apoptosis
Züllig, Stephanie, Neukomm, Lukas J., Jovanovic, Marko, Charette, Steve J., Lyssenko, Nicholas N., Halleck, Margaret S., Reutelingsperger, Chris P.M., Schlegel, Robert A., Hengartner, Michael O.
Published in Current biology (05.06.2007)
Published in Current biology (05.06.2007)
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Journal Article
ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion
Bi, Xin, Pashos, Evanthia E., Cuchel, Marina, Lyssenko, Nicholas N., Hernandez, Mayda, Picataggi, Antonino, McParland, James, Yang, Wenli, Liu, Ying, Yan, Ruilan, Yu, Christopher, DerOhannessian, Stephanie L., Phillips, Michael C., Morrisey, Edward E., Duncan, Stephen A., Rader, Daniel J.
Published in EBioMedicine (01.04.2017)
Published in EBioMedicine (01.04.2017)
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Journal Article
The Alzheimer’s disease GWAS risk alleles in the ABCA7 promoter and 5’ region reduce ABCA7 expression
Lyssenko, Nicholas N., Shi, Xinghua, Praticò, Domenico
Published in Acta neuropathologica (01.09.2022)
Published in Acta neuropathologica (01.09.2022)
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Journal Article
Very low levels of ABCA7 in the cerebrum and Alzheimer’s disease onset between the ages of 60 and 80 independently of APOE
Garliyev, Viktor, Lyssenko, Catherine A, Wiener, Joel P, Praticò, Domenico, Lyssenko, Nicholas N
Published in Journal of neuropathology and experimental neurology (01.10.2024)
Published in Journal of neuropathology and experimental neurology (01.10.2024)
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Journal Article
Arabidopsis repressor of light signaling, COP1, is regulated by nuclear exclusion: mutational analysis by bioluminescence resonance energy transfer
Subramanian, C, Kim, B.H, Lyssenko, N.N, Xu, X, Johnson, C.H, Arnim, A.G. von
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2004)
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Journal Article
Specificity of ABCA7-mediated cell lipid efflux
Picataggi, Antonino, Rodrigues, Amrith, Cromley, Debra A., Wang, Hu, Wiener, Joel P., Garliyev, Viktor, Billheimer, Jeffrey T., Grabiner, Brian C., Hurt, Jessica A., Chen, Allen C., Han, Xianlin, Rader, Daniel J., Praticò, Domenico, Lyssenko, Nicholas N.
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.07.2022)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.07.2022)
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Journal Article
Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics
Khoshnejad, Makan, Patel, Ami, Wojtak, Krzysztof, Kudchodkar, Sagar B., Humeau, Laurent, Lyssenko, Nicholas N., Rader, Daniel J., Muthumani, Kar, Weiner, David B.
Published in Molecular therapy (02.01.2019)
Published in Molecular therapy (02.01.2019)
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Journal Article
An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases
Lyssenko, Nicholas N, Miteva, Yana, Gilroy, Simon, Hanna-Rose, Wendy, Schlegel, Robert A
Published in BMC developmental biology (02.10.2008)
Published in BMC developmental biology (02.10.2008)
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Journal Article
Factors controlling nascent high‐density lipoprotein particle heterogeneity: ATP‐binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability
Lyssenko, Nicholas N., Nickel, Margaret, Tang, Chongren, Phillips, Michael C.
Published in The FASEB journal (01.07.2013)
Published in The FASEB journal (01.07.2013)
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Journal Article
Functional Analysis of Regulatory Elements in the Gene Promoter for an Abscission-Specific Cellulase from Bean and Isolation, Expression, and Binding Affinity of Three TGA-Type Basic Leucine Zipper Transcription Factors
Mark L. Tucker, Whitelaw, Catherine A., Lyssenko, Nicholas N., Pravendra Nath
Published in Plant physiology (Bethesda) (01.11.2002)
Published in Plant physiology (Bethesda) (01.11.2002)
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Journal Article
Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease
Cipollari, Eleonora, Szapary, Hannah J, Picataggi, Antonino, Billheimer, Jeffrey T, Lyssenko, Catherine A, Ying, Gui-Shuang, Shaw, Leslie M, Kling, Mitchel A, Kaddurah-Daouk, Rima, Rader, Daniel J, Praticò, Domenico, Lyssenko, Nicholas N
Published in Journal of Alzheimer's disease (01.01.2020)
Published in Journal of Alzheimer's disease (01.01.2020)
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Journal Article
Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality
Lyssenko, Nicholas N., Hata, Mami, Dhanasekaran, Padmaja, Nickel, Margaret, Nguyen, David, Chetty, Palaniappan Sevugan, Saito, Hiroyuki, Lund-Katz, Sissel, Phillips, Michael C.
Published in Biochimica et biophysica acta (01.03.2012)
Published in Biochimica et biophysica acta (01.03.2012)
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Journal Article