Iridium-Catalyzed Enantioselective Synthesis of Allylic Alcohols: Silanolates as Hydroxide Equivalents
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Published in Angewandte Chemie (18.09.2006)
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Design of Dual EP2/EP4 Antagonists through Scaffold Merging of Selective Inhibitors
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Published in ChemMedChem (15.01.2024)
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Abstract 1809: ACT-1002-4391 - A novel potent antagonist of the prostaglandin E2 receptors EP2 and EP4 with excellent duality
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Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Corrigendum to “Syntheses of disaccharide- and nucleoside-substituted cyclopentadienyl and indenyl ligands” [Inorg. Chim. Acta 350 (2003) 568–576]
Laï, Richard, Berthome, Jean-Francois, Lyothier, Isabelle, Scheidecker, Celine, Martin, Sandrine
Published in Inorganica Chimica Acta (01.09.2014)
Published in Inorganica Chimica Acta (01.09.2014)
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N-치환된 인돌 유도체
LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, POTHIER JULIEN, SIFFERLEN THIERRY
Year of Publication 20.01.2020
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Year of Publication 20.01.2020
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The Tubulin-Bound Conformation of Discodermolide Derived by NMR Studies in Solution Supports a Common Pharmacophore Model for Epothilone and Discodermolide
Sánchez-Pedregal, Víctor M., Kubicek, Karel, Meiler, Jens, Lyothier, Isabelle, Paterson, Ian, Carlomagno, Teresa
Published in Angewandte Chemie (International ed.) (13.11.2006)
Published in Angewandte Chemie (International ed.) (13.11.2006)
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PGE2 수용체 조절제로서의 페닐 유도체
CORMINBOEUF OLIVIER, POZZI DAVIDE, LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, SIFFERLEN THIERRY, BOSS CHRISTOPH, SIENDT HERVE
Year of Publication 30.01.2020
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Year of Publication 30.01.2020
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PGE2 수용체 조절제로서의 피리미딘 유도체
CORMINBOEUF OLIVIER, POZZI DAVIDE, LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, SIFFERLEN THIERRY, BOSS CHRISTOPH, SIENDT HERVE
Year of Publication 22.01.2020
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Year of Publication 22.01.2020
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피리미딘 유도체
CORMINBOEUF OLIVIER, POZZI DAVIDE, LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, SIFFERLEN THIERRY, BOSS CHRISTOPH, SIENDT HERVE
Year of Publication 21.01.2020
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Year of Publication 21.01.2020
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PGE2 수용체 조절제로서의 벤조푸란 및 벤조티오페논 유도체
CORMINBOEUF OLIVIER, POZZI DAVIDE, LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, SIFFERLEN THIERRY, BOSS CHRISTOPH, SIENDT HERVE
Year of Publication 21.01.2020
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Year of Publication 21.01.2020
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Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: A Potent, Orally Bioavailable Human CB1/CB2 Dual Agonist with Antihyperalgesic Properties and Restricted Central Nervous System Penetration
Dziadulewicz, Edward K, Bevan, Stuart J, Brain, Christopher T, Coote, Paul R, Culshaw, Andrew J, Davis, Andrew J, Edwards, Lee J, Fisher, Adrian J, Fox, Alyson J, Gentry, Clive, Groarke, Alex, Hart, Terance W, Huber, Werner, James, Iain F, Kesingland, Adam, La Vecchia, Luigi, Loong, Yvonne, Lyothier, Isabelle, McNair, Kara, O'Farrell, Cathal, Peacock, Marcus, Portmann, Robert, Schopfer, Ulrich, Yaqoob, Mohammed, Zadrobilek, Jiri
Published in Journal of medicinal chemistry (09.08.2007)
Published in Journal of medicinal chemistry (09.08.2007)
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A Second-Generation Total Synthesis of (+)-Discodermolide: The Development of a Practical Route Using Solely Substrate-Based Stereocontrol
Paterson, Ian, Delgado, Oscar, Florence, Gordon J, Lyothier, Isabelle, O'Brien, Matthew, Scott, Jeremy P, Sereinig, Natascha
Published in Journal of organic chemistry (07.01.2005)
Published in Journal of organic chemistry (07.01.2005)
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PGE2 수용체 조절제로서의 N-치환된 인돌 유도체
CORMINBOEUF OLIVIER, POZZI DAVIDE, LYOTHIER ISABELLE, RICHARD BILDSTEIN SYLVIA, FRETZ HEINZ, WYDER PETERS LORENZA, POTHIER JULIEN, SIFFERLEN THIERRY
Year of Publication 17.07.2018
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Year of Publication 17.07.2018
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1,6-Asymmetric Induction in Boron-Mediated Aldol Reactions: Application to a Practical Total Synthesis of (+)-Discodermolide
Paterson, Ian, Delgado, Oscar, Florence, Gordon J., Lyothier, Isabelle, Scott, Jeremy P., Sereinig, Natascha
Published in Organic letters (09.01.2003)
Published in Organic letters (09.01.2003)
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Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 5: Linkage of Fragments C1 - 6 and C7 - 24 and Finale
Mickel, Stuart J, Niederer, Daniel, Daeffler, Robert, Osmani, Adnan, Kuesters, Ernst, Schmid, Emil, Schaer, Karl, Gamboni, Remo, Chen, Weichun, Loeser, Eric, Kinder, Frederick R, Konigsberger, Kurt, Prasad, Kapa, Ramsey, Timothy M, Repič, Oljan, Wang, Run-Ming, Florence, Gordon, Lyothier, Isabelle, Paterson, Ian
Published in Organic process research & development (16.01.2004)
Published in Organic process research & development (16.01.2004)
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Identification and Biological Characterization of 6-Aryl-7-isopropylquinazolinones as Novel TRPV1 Antagonists that Are Effective in Models of Chronic Pain
Culshaw, Andrew J, Bevan, Stuart, Christiansen, Martin, Copp, Prafula, Davis, Andrew, Davis, Clare, Dyson, Alex, Dziadulewicz, Edward K, Edwards, Lee, Eggelte, Hendrikus, Fox, Alyson, Gentry, Clive, Groarke, Alex, Hallett, Allan, Hart, Terance W, Hughes, Glyn A, Knights, Sally, Kotsonis, Peter, Lee, Wai, Lyothier, Isabelle, McBryde, Andrew, McIntyre, Peter, Paloumbis, George, Panesar, Moh, Patel, Sadhana, Seiler, Max-Peter, Yaqoob, Mohammed, Zimmermann, Kaspar
Published in Journal of medicinal chemistry (26.01.2006)
Published in Journal of medicinal chemistry (26.01.2006)
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4,4-DISUBSTITUTED PIPERIDINES
JOTTERAND NATHALIE, MAH ROBERT, LYOTHIER ISABELLE, TSCHINKE VINCENZO, STUTZ STEFAN, HEROLD PETER, JELAKOVIC STJEPAN, BEHNKE DIRK
Year of Publication 28.07.2010
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Year of Publication 28.07.2010
Patent