Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H F, Nasteska, Daniela, Ashford, Fiona B, Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J, Lucey, Maria A, Sasaki, Shugo, Brierley, Daniel I, Hastoy, Benoit, Tomas, Alejandra, D'Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C, Reissaus, Christopher A, Linnemann, Amelia K, D'Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J
Published in Nature communications (24.01.2020)
Published in Nature communications (24.01.2020)
Get full text
Journal Article
Friend and foe: β-cell Ca2+ signaling and the development of diabetes
Sabatini, Paul V., Speckmann, Thilo, Lynn, Francis C.
Published in Molecular metabolism (Germany) (01.03.2019)
Published in Molecular metabolism (Germany) (01.03.2019)
Get full text
Journal Article
Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation
Szabat, Marta, Page, Melissa M., Panzhinskiy, Evgeniy, Skovsø, Søs, Mojibian, Majid, Fernandez-Tajes, Juan, Bruin, Jennifer E., Bround, Michael J., Lee, Jason T.C., Xu, Eric E., Taghizadeh, Farnaz, O’Dwyer, Shannon, van de Bunt, Martijn, Moon, Kyung-Mee, Sinha, Sunita, Han, Jun, Fan, Yong, Lynn, Francis C., Trucco, Massimo, Borchers, Christoph H., Foster, Leonard J., Nislow, Corey, Kieffer, Timothy J., Johnson, James D.
Published in Cell metabolism (12.01.2016)
Published in Cell metabolism (12.01.2016)
Get full text
Journal Article
PDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system
Zhao, Jia, Liang, Shenghui, Cen, Haoning Howard, Li, Yanjun, Baker, Robert K, Ruprai, Balwinder, Gao, Guang, Zhang, Chloe, Ren, Huixia, Tang, Chao, Chen, Liangyi, Liu, Yanmei, Lynn, Francis C, Johnson, James D, Kieffer, Timothy J
Published in Nature communications (13.07.2024)
Published in Nature communications (13.07.2024)
Get full text
Journal Article
MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse
LYNN, Francis C, SKEWES-COX, Peter, KOSAKA, Yasuhiro, MCMANUS, Michael T, HARFE, Brian D, GERMAN, Michael S
Published in Diabetes (New York, N.Y.) (01.12.2007)
Published in Diabetes (New York, N.Y.) (01.12.2007)
Get full text
Journal Article
Recapitulating pancreatic cell–cell interactions through bioengineering approaches: the momentous role of non-epithelial cells for diabetes cell therapy
Ghezelayagh, Zahra, Zabihi, Mahsa, Kazemi Ashtiani, Mohammad, Ghezelayagh, Zeinab, Lynn, Francis C., Tahamtani, Yaser
Published in Cellular and molecular life sciences : CMLS (01.12.2021)
Published in Cellular and molecular life sciences : CMLS (01.12.2021)
Get full text
Journal Article
RETRACTED ARTICLE: Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes
Yoon, Ji Soo, Sasaki, Shugo, Velghe, Jane, Lee, Michelle Y. Y., Winata, Helena, Nian, Cuilan, Lynn, Francis C.
Published in Diabetologia (01.09.2022)
Published in Diabetologia (01.09.2022)
Get full text
Journal Article
Rfx6 directs islet formation and insulin production in mice and humans
Polychronakos, Constantin, German, Michael S, Smith, Stuart B, Qu, Hui-Qi, Taleb, Nadine, Kishimoto, Nina Y, Scheel, David W, Lu, Yang, Patch, Ann-Marie, Grabs, Rosemary, Wang, Juehu, Lynn, Francis C, Miyatsuka, Takeshi, Mitchell, John, Seerke, Rina, Désir, Julie, Eijnden, Serge Vanden, Abramowicz, Marc, Kacet, Nadine, Weill, Jacques, Renard, Marie-Ève, Gentile, Mattia, Hansen, Inger, Dewar, Ken, Hattersley, Andrew T, Wang, Rennian, Wilson, Maria E, Johnson, Jeffrey D
Published in Nature (London) (11.02.2010)
Published in Nature (London) (11.02.2010)
Get full text
Journal Article
Npas4 Transcription Factor Expression Is Regulated by Calcium Signaling Pathways and Prevents Tacrolimus-induced Cytotoxicity in Pancreatic Beta Cells
Speckmann, Thilo, Sabatini, Paul V., Nian, Cuilan, Smith, Riley G., Lynn, Francis C.
Published in The Journal of biological chemistry (05.02.2016)
Published in The Journal of biological chemistry (05.02.2016)
Get full text
Journal Article
Spatial and transcriptional heterogeneity of pancreatic beta cell neogenesis revealed by a time-resolved reporter system
Sasaki, Shugo, Lee, Michelle Y. Y., Wakabayashi, Yuka, Suzuki, Luka, Winata, Helena, Himuro, Miwa, Matsuoka, Taka-aki, Shimomura, Iichiro, Watada, Hirotaka, Lynn, Francis C., Miyatsuka, Takeshi
Published in Diabetologia (01.05.2022)
Published in Diabetologia (01.05.2022)
Get full text
Journal Article
Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization
Whitaker, Gina M, Lynn, Francis C, McIntosh, Christopher H S, Accili, Eric A
Published in PloS one (07.03.2012)
Published in PloS one (07.03.2012)
Get full text
Journal Article
An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells
Bayly, Carmen L., Dai, Xiao-Qing, Nian, Cuilan, Orban, Paul C., Verchere, C. Bruce, MacDonald, Patrick E., Lynn, Francis C.
Published in Molecular metabolism (Germany) (01.11.2024)
Published in Molecular metabolism (Germany) (01.11.2024)
Get full text
Journal Article
Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells
Bruin, Jennifer E., Erener, Suheda, Vela, Javier, Hu, Xiaoke, Johnson, James D., Kurata, Harley T., Lynn, Francis C., Piret, James M., Asadi, Ali, Rezania, Alireza, Kieffer, Timothy J.
Published in Stem cell research (01.01.2014)
Published in Stem cell research (01.01.2014)
Get full text
Journal Article
Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8)
Ejarque, Miriam, Mir-Coll, Joan, Gomis, Ramon, German, Michael S, Lynn, Francis C, Gasa, Rosa
Published in PloS one (11.01.2016)
Published in PloS one (11.01.2016)
Get full text
Journal Article
TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation
Campbell, Stephanie A., McDonald, Cassandra L., Krentz, Nicole A.J., Lynn, Francis C., Hoffman, Brad G.
Published in Cell reports (Cambridge) (13.08.2019)
Published in Cell reports (Cambridge) (13.08.2019)
Get full text
Journal Article
Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive optic atrophy
McMillan, Hugh J, Telegrafi, Aida, Singleton, Amanda, Cho, Megan T, Lelli, Daniel, Lynn, Francis C, Griffin, Julie, Asamoah, Alexander, Rinne, Tuula, Erasmus, Corrie E, Koolen, David A, Haaxma, Charlotte A, Keren, Boris, Doummar, Diane, Mignot, Cyril, Thompson, Islay, Velsher, Lea, Dehghani, Mohammadreza, Vahidi Mehrjardi, Mohammad Yahya, Maroofian, Reza, Tchan, Michel, Simons, Cas, Christodoulou, John, Martín-Hernández, Elena, Guillen Sacoto, Maria J, Henderson, Lindsay B, McLaughlin, Heather, Molday, Laurie L, Molday, Robert S, Yoon, Grace
Published in Orphanet journal of rare diseases (31.05.2018)
Published in Orphanet journal of rare diseases (31.05.2018)
Get full text
Journal Article