Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells
Lynch, Katherine D, Iverson, Dayne T, Bachhav, Namrata K, Call, Michael Ridge, Yue, Guihua Eileen, Prasad, Bhagwat, Clarke, John D
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Journal Article
Sub-Chronic Microcystin-LR Liver Toxicity in Preexisting Diet-Induced Nonalcoholic Steatohepatitis in Rats
Arman, Tarana, Lynch, Katherine D, Montonye, Michelle L, Goedken, Michael, Clarke, John D
Published in Toxins (09.07.2019)
Published in Toxins (09.07.2019)
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Journal Article
Recurrent die-offs of adult coho salmon returning to spawn in Puget Sound lowland urban streams
Scholz, Nathaniel L, Myers, Mark S, McCarthy, Sarah G, Labenia, Jana S, McIntyre, Jenifer K, Ylitalo, Gina M, Rhodes, Linda D, Laetz, Cathy A, Stehr, Carla M, French, Barbara L, McMillan, Bill, Wilson, Dean, Reed, Laura, Lynch, Katherine D, Damm, Steve, Davis, Jay W, Collier, Tracy K
Published in PloS one (14.12.2011)
Published in PloS one (14.12.2011)
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Journal Article
Invertebrate and Microbial Response to Hyporheic Restoration of an Urban Stream
Morley, Sarah A, Rhodes, Linda D, Baxter, Anne E, Goetz, Giles W, Wells, Abigail H, Lynch, Katherine D
Published in Water (Basel) (01.02.2021)
Published in Water (Basel) (01.02.2021)
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Journal Article
Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet
Arman, Tarana, Lynch, Katherine D., Goedken, Michael, Clarke, John D.
Published in Chemosphere (Oxford) (01.04.2021)
Published in Chemosphere (Oxford) (01.04.2021)
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Journal Article
MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-induced nonalcoholic steatohepatitis through a 4-week recovery period
Arman, Tarana, Baron, J. Allen, Lynch, Katherine D., White, Laura A., Aldan, Johnny, Clarke, John D.
Published in Toxicology (Amsterdam) (01.12.2021)
Published in Toxicology (Amsterdam) (01.12.2021)
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Journal Article
Microcystin-LR activates serine/threonine kinases and alters the phosphoproteome in human HepaRG cells
Ikumawoyi, Victor O., Lynch, Katherine D., Iverson, Dayne T., Call, M. Ridge, Yue, Guihua Eileen, Prasad, Bhagwat, Clarke, John D.
Published in Toxicon (Oxford) (01.10.2024)
Published in Toxicon (Oxford) (01.10.2024)
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Journal Article
Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice
Oyanna, Victoria O., Bechtold, Baron J., Lynch, Katherine D., Ridge Call, M., Graf, Tyler N., Oberlies, Nicholas H., Clarke, John D.
Published in Pharmaceutical research (01.03.2024)
Published in Pharmaceutical research (01.03.2024)
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Journal Article
Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice
Bechtold, Baron J, Lynch, Katherine D, Oyanna, Victoria O, Call, M Ridge, White, Laura A, Graf, Tyler N, Oberlies, Nicholas H, Clarke, John D
Published in Drug metabolism and disposition (01.05.2024)
Published in Drug metabolism and disposition (01.05.2024)
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Journal Article
Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model
Bechtold, Baron J., Lynch, Katherine D., Oyanna, Victoria O., Call, M. Ridge, Graf, Tyler N., Oberlies, Nicholas H., Clarke, John D.
Published in Molecular pharmaceutics (06.05.2024)
Published in Molecular pharmaceutics (06.05.2024)
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Journal Article
A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model
Montonye, Michelle L, Tian, Dan-Dan, Arman, Tarana, Lynch, Katherine D, Hagenbuch, Bruno, Paine, Mary F, Clarke, John D
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
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Journal Article
Goldenseal-mediated inhibition of intestinal uptake transporters decreases metformin systemic exposure in mice
Oyanna, Victoria O, Garcia-Torres, Kenisha Y, Bechtold, Baron J, Lynch, Katherine D, Call, M Ridge, Horváth, Miklós, Manwill, Preston K, Graf, Tyler N, Cech, Nadja B, Oberlies, Nicholas H, Paine, Mary F, Clarke, John D
Published in Drug metabolism and disposition (01.11.2023)
Published in Drug metabolism and disposition (01.11.2023)
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Journal Article
Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity
Clarke, John D., Dzierlenga, Anika, Arman, Tarana, Toth, Erica, Li, Hui, Lynch, Katherine D., Tian, Dan-Dan, Goedken, Michael, Paine, Mary F., Cherrington, Nathan
Published in Toxicon (Oxford) (15.04.2019)
Published in Toxicon (Oxford) (15.04.2019)
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Journal Article
Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions
Lynch, Katherine D., Montonye, Michelle L., Tian, Dan‐Dan, Arman, Tarana, Oyanna, Victoria O., Bechtold, Baron J., Graf, Tyler N., Oberlies, Nicholas H., Paine, Mary F., Clarke, John D.
Published in Phytotherapy research (01.06.2021)
Published in Phytotherapy research (01.06.2021)
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Journal Article
Effectiveness monitoring of juvenile Chinook salmon restoration projects in south Lake Washington, Washington State
Tabor, Roger A., Liermann, Martin C., Gearns, Howard A., Moore, Zachary J., Lynch, Katherine D., Kurko, Keith, Crittenden, Julie, Shoemaker, Monica E.
Published in Lake and reservoir management (09.06.2022)
Published in Lake and reservoir management (09.06.2022)
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Journal Article
Characterization of Mesoamerican Nephropathy in a Kidney Failure Hotspot in Nicaragua
Kupferman, Joseph, MD, Amador, Juan José, MD, MPH, Lynch, Katherine E., MD, SM, Laws, Rebecca L., PhD, MPH, López-Pilarte, Damaris, MPH, Ramírez-Rubio, Oriana, MD, MPH, PhD, Kaufman, James S., MD, Lau, Jorge Luis, MD, Weiner, Daniel E., MD, MS, Robles, Ninoska Violeta, BS, Verma, Karina P., BA, Scammell, Madeleine K., DSc, McClean, Michael D., ScD, Brooks, Daniel R., DSc, Friedman, David J., MD
Published in American journal of kidney diseases (01.11.2016)
Published in American journal of kidney diseases (01.11.2016)
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Journal Article
Altered taste perception and nutritional status among hemodialysis patients
Lynch, Katherine E, Lynch, Rebecca, Curhan, Gary C, Brunelli, Steven M
Published in Journal of renal nutrition (01.07.2013)
Published in Journal of renal nutrition (01.07.2013)
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Journal Article