Five-Year Efficacy and Safety of Ustekinumab Treatment in Crohn’s Disease: The IM-UNITI Trial
Sandborn, William J., Rebuck, Rory, Wang, Yuhua, Zou, Bin, Adedokun, Omoniyi J., Gasink, Christopher, Sands, Bruce E., Hanauer, Stephen B., Targan, Stephan, Ghosh, Subrata, de Villiers, Willem J.S., Colombel, Jean-Frederic, Feagan, Brian G., Lynch, John P.
Published in Clinical gastroenterology and hepatology (01.03.2022)
Published in Clinical gastroenterology and hepatology (01.03.2022)
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Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
McAfee, Quentin, Zhang, Zhihui, Samanta, Arabinda, Levi, Samuel M, Ma, Xiao-Hong, Piao, Shengfu, Lynch, John P, Uehara, Takeshi, Sepulveda, Antonia R, Davis, Lisa E, Winkler, Jeffrey D, Amaravadi, Ravi K
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2012)
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KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF
Shaverdashvili, Khvaramze, Padlo, Jennie, Weinblatt, Daniel, Jia, Yang, Jiang, Wenpeng, Rao, Divya, Laczkó, Dorottya, Whelan, Kelly A, Lynch, John P, Muir, Amanda B, Katz, Jonathan P
Published in PloS one (18.04.2019)
Published in PloS one (18.04.2019)
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Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche
Yang, Ting-Lin B, Chen, Qijun, Deng, Jennifer T, Jagannathan, Geetha, Tobias, John W, Schultz, David C, Wang, Shan, Lengner, Christopher J, Rustgi, Anil K, Lynch, John P, Johnson, F Brad
Published in Nature communications (17.03.2017)
Published in Nature communications (17.03.2017)
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Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus
Stairs, Douglas B, Nakagawa, Hiroshi, Klein-Szanto, Andres, Mitchell, Shukriyyah D, Silberg, Debra G, Tobias, John W, Lynch, John P, Rustgi, Anil K
Published in PloS one (27.10.2008)
Published in PloS one (27.10.2008)
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Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4
Vega, Maria E, Giroux, Véronique, Natsuizaka, Mitsuteru, Liu, Mingen, Klein-Szanto, Andres J, Stairs, Douglas B, Nakagawa, Hiroshi, Wang, Kenneth K, Wang, Timothy C, Lynch, John P, Rustgi, Anil K
Published in Cell cycle (Georgetown, Tex.) (15.12.2014)
Published in Cell cycle (Georgetown, Tex.) (15.12.2014)
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Increasing the Complexity of Organoid Cultures: Current Status and Future Challenges
Lynch, John P., MD, PhD
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions
Verzi, Michael P., Hatzis, Pantelis, Sulahian, Rita, Philips, Juliet, Schuijers, Jurian, Shin, Hyunjin, Freed, Ellen, Lynch, John P., Dang, Duyen T., Brown, Myles, Clevers, Hans, Liu, X. Shirley, Shivdasan, Ramesh A., Olson, Eric N.
Published in Proceedings of the National Academy of Sciences - PNAS (24.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (24.08.2010)
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A Randomized Controlled Trial of Tacrolimus Versus Cyclosporine After Lung Transplantation
Hachem, Ramsey R., MD, Yusen, Roger D., MD, MPH, Chakinala, Murali M., MD, Meyers, Bryan F., MD, MPH, Lynch, John P., MD, Aloush, Aviva A., RN, Patterson, G. Alexander, MD, Trulock, Elbert P., MD
Published in The Journal of heart and lung transplantation (01.10.2007)
Published in The Journal of heart and lung transplantation (01.10.2007)
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Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress
Kong, Jianping, Whelan, Kelly A., Laczkó, Dorottya, Dang, Brendan, Caro Monroig, Angeliz, Soroush, Ali, Falcone, John, Amaravadi, Ravi K., Rustgi, Anil K., Ginsberg, Gregory G., Falk, Gary W., Nakagawa, Hiroshi, Lynch, John P.
Published in Molecular carcinogenesis (01.11.2016)
Published in Molecular carcinogenesis (01.11.2016)
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Organoids and Engineered Organ Systems
Samuelson, Linda C., PhD, Lynch, John P., MD
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Repression of the Desmocollin 2 Gene Expression in Human Colon Cancer Cells Is Relieved by the Homeodomain Transcription Factors Cdx1 and Cdx2
Funakoshi, Shinsuke, Ezaki, Toshihiko, Kong, Jianping, Guo, Rong Jun, Lynch, John P
Published in Molecular cancer research (01.09.2008)
Published in Molecular cancer research (01.09.2008)
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Cox2 and β-Catenin/T-cell Factor Signaling Intestinalize Human Esophageal Keratinocytes When Cultured under Organotypic Conditions
Kong, Jianping, Crissey, Mary Ann S, Stairs, Douglas B, Sepulveda, Antonia R, Lynch, John P
Published in Neoplasia (New York, N.Y.) (01.09.2011)
Published in Neoplasia (New York, N.Y.) (01.09.2011)
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Modelling Barrett's oesophagus
Kong, Jianping, Stairs, Douglas B, Lynch, John P
Published in Biochemical Society transactions (01.04.2010)
Published in Biochemical Society transactions (01.04.2010)
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Right and Left Ventricular Dysfunction in Patients With Severe Pulmonary Disease
Vizza, Carmine Dario, Lynch, John P., Ochoa, Laura L., Richardson, Gregory, Trulock, Elbert P.
Published in Chest (01.03.1998)
Published in Chest (01.03.1998)
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A Comparison of Basiliximab and Anti-Thymocyte Globluin as Induction Agents After Lung Transplantation
Hachem, Ramsey R., Chakinala, Murali M., Yusen, Roger D., Lynch, John P., Aloush, Aviva A., Patterson, G. Alexander, Trulock, Elbert P.
Published in The Journal of heart and lung transplantation (01.09.2005)
Published in The Journal of heart and lung transplantation (01.09.2005)
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