Structure-based design of a phosphotyrosine-masked covalent ligand targeting the E3 ligase SOCS2
Ramachandran, Sarath, Makukhin, Nikolai, Haubrich, Kevin, Nagala, Manjula, Forrester, Beth, Lynch, Dylan M., Casement, Ryan, Testa, Andrea, Bruno, Elvira, Gitto, Rosaria, Ciulli, Alessio
Published in Nature communications (10.10.2023)
Published in Nature communications (10.10.2023)
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Journal Article
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
Kroupova, Alena, Spiteri, Valentina A., Rutter, Zoe J., Furihata, Hirotake, Darren, Darren, Ramachandran, Sarath, Chakraborti, Sohini, Haubrich, Kevin, Pethe, Julie, Gonzales, Denzel, Wijaya, Andre J., Rodriguez-Rios, Maria, Sturbaut, Manon, Lynch, Dylan M., Farnaby, William, Nakasone, Mark A., Zollman, David, Ciulli, Alessio
Published in Nature communications (15.10.2024)
Published in Nature communications (15.10.2024)
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Journal Article
The pro-drug C13 activates AMPK by two distinct mechanisms
Freemantle, Jordana B, Shah, Dinesh, Lynch, Dylan M, Ciulli, Alessio, Hundal, Harinder S, Hardie, D Grahame
Published in Biochemical journal (18.09.2024)
Published in Biochemical journal (18.09.2024)
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Journal Article
Traceless Thioacid-Mediated Radical Cyclization of 1,6-Dienes
Lynch, Dylan M., Nolan, Mark D., Williams, Conor, Van Dalsen, Leendert, Calvert, Susannah H., Dénès, Fabrice, Trujillo, Cristina, Scanlan, Eoin M.
Published in Journal of organic chemistry (21.07.2023)
Published in Journal of organic chemistry (21.07.2023)
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Journal Article
Glycosylated quantum dots as fluorometric nanoprobes for trehalase
Barnes, Danielle D, Kuznetsova, Vera, Visheratina, Anastasia, Purcell-Milton, Finn, Baranov, Mikhail A, Lynch, Dylan M, Martin, Harlei, Gun'ko, Yurii K, Scanlan, Eoin M
Published in Organic & biomolecular chemistry (05.04.2023)
Published in Organic & biomolecular chemistry (05.04.2023)
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Journal Article
Real‐Time Multi‐Photon Tracking and Bioimaging of Glycosylated Theranostic Prodrugs upon Specific Enzyme Triggered Release
Calatrava‐Pérez, Elena, Marchetti, Luke A., McManus, Gavin J., Lynch, Dylan M., Elmes, Robert B. P., Williams, D. Clive, Gunnlaugsson, Thorfinnur, Scanlan, Eoin M.
Published in Chemistry : a European journal (13.01.2022)
Published in Chemistry : a European journal (13.01.2022)
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Journal Article
Unravelling the druggability and immunological roles of the SOCS-family proteins
Lynch, Dylan M, Forrester, Beth, Webb, Thomas, Ciulli, Alessio
Published in Frontiers in immunology (01.11.2024)
Published in Frontiers in immunology (01.11.2024)
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Journal Article
Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory
Lundahl, Mimmi, Lynch, Dylan M, Barnes, Danielle, McSweeney, Lauren, Gorman, Aoife, Lebre, Filipa, Gordon, Stephen V, Lavelle, Ed C, Scanlan, Eoin M
Published in ACS chemical biology (18.09.2020)
Published in ACS chemical biology (18.09.2020)
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Journal Article
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
Kroupova, Alena, Spiteri, Valentina A, Furihata, Hirotake, Darren, Darren, Ramachandran, Sarath, Rutter, Zoe, Chakraborti, Sohini, Haubrich, Kevin, Pethe, Julie, Gonzales, Denzel, Wijaya, Andre, Rodriguez-Rios, Maria, Lynch, Dylan M, Farnaby, William, Nakasone, Mark, Zollman, David, Ciulli, Alessio
Published in bioRxiv (20.01.2024)
Published in bioRxiv (20.01.2024)
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