Usnic acid and its derivatives for pharmaceutical use: a patent review (2000-2017)
Luzina, Olga A, Salakhutdinov, Nariman F
Published in Expert opinion on therapeutic patents (03.06.2018)
Published in Expert opinion on therapeutic patents (03.06.2018)
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Journal Article
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1
Zakharenko, Alexandra L, Luzina, Olga A, Chepanova, Arina A, Dyrkheeva, Nadezhda S, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Carbonylation of Polyfluorinated 1-Arylalkan-1-ols and Diols in Superacids
Wang, Siqi, Zonov, Yaroslav V, Karpov, Victor M, Luzina, Olga A, Mezhenkova, Tatyana V
Published in Molecules (Basel, Switzerland) (01.12.2022)
Published in Molecules (Basel, Switzerland) (01.12.2022)
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Journal Article
Triterpenic Acid Amides as Potential Inhibitors of the SARS-CoV-2 Main Protease
Baev, Dmitry S, Blokhin, Mikhail E, Chirkova, Varvara Yu, Belenkaya, Svetlana V, Luzina, Olga A, Yarovaya, Olga I, Salakhutdinov, Nariman F, Shcherbakov, Dmitry N
Published in Molecules (Basel, Switzerland) (30.12.2022)
Published in Molecules (Basel, Switzerland) (30.12.2022)
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Journal Article
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
Filimonov, Aleksander S, Chepanova, Arina A, Luzina, Olga A, Zakharenko, Alexandra L, Zakharova, Olga D, Ilina, Ekaterina S, Dyrkheeva, Nadezhda S, Kuprushkin, Maxim S, Kolotaev, Anton V, Khachatryan, Derenik S, Patel, Jinal, Leung, Ivanhoe K H, Chand, Raina, Ayine-Tora, Daniel M, Reynisson, Johannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (15.10.2019)
Published in Molecules (Basel, Switzerland) (15.10.2019)
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Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives
Kornienko, Tatyana E, Chepanova, Arina A, Zakharenko, Alexandra L, Filimonov, Aleksandr S, Luzina, Olga A, Dyrkheeva, Nadezhda S, Nikolin, Valeriy P, Popova, Nelly A, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.01.2024)
Published in International journal of molecular sciences (01.01.2024)
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Journal Article
Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety
Kuranov, Sergey O, Pon Kina, Darya A, Meshkova, Yulia V, Marenina, Mariya K, Khvostov, Mikhail V, Luzina, Olga A, Tolstikova, Tatiana G, Salakhutdinov, Nariman F
Published in International journal of molecular sciences (28.04.2023)
Published in International journal of molecular sciences (28.04.2023)
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Journal Article
Regioselectivity Amination of Usnic Acid by Ammonia in Water
Filimonov, Aleksandr, Luzina, Olga, Gatilov, Yuri, Salakhutdinov, Nariman
Published in MolBank (01.06.2023)
Published in MolBank (01.06.2023)
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Journal Article
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties
Ivankin, Dmitry I, Kornienko, Tatyana E, Mikhailova, Marina A, Dyrkheeva, Nadezhda S, Zakharenko, Alexandra L, Achara, Chigozie, Reynisson, Jóhannes, Golyshev, Victor M, Luzina, Olga A, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Journal Article
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors
Gladkova, Elizaveta D, Chepanova, Arina A, Ilina, Ekaterina S, Zakharenko, Alexandra L, Reynisson, Jóhannes, Luzina, Olga A, Volcho, Konstantin P, Lavrik, Olga I, Salakhutdinov, Nariman F
Published in Molecules (Basel, Switzerland) (30.03.2021)
Published in Molecules (Basel, Switzerland) (30.03.2021)
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Journal Article
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
Dyrkheeva, Nadezhda S, Filimonov, Aleksandr S, Luzina, Olga A, Orlova, Kristina A, Chernyshova, Irina A, Kornienko, Tatyana E, Malakhova, Anastasia A, Medvedev, Sergey P, Zakharenko, Alexandra L, Ilina, Ekaterina S, Anarbaev, Rashid O, Naumenko, Konstantin N, Klabenkova, Kristina V, Burakova, Ekaterina A, Stetsenko, Dmitry A, Zakian, Suren M, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (20.10.2021)
Published in International journal of molecular sciences (20.10.2021)
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Journal Article
Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and docking
Ivankin, Dmitry I., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Ilina, Ekaterina S., Zarkov, Timofey O., Reynisson, Jóhannes, Luzina, Olga A., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Bioorganic & medicinal chemistry letters (01.10.2022)
Published in Bioorganic & medicinal chemistry letters (01.10.2022)
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Journal Article
Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan
Okhina, Alina A., Kornienko, Tatyana E., Rogachev, Artem D., Luzina, Olga A., Popova, Nelly A., Nikolin, Valery P., Zakharenko, Alexandra L., Dyrkheeva, Nadezhda S., Pokrovsky, Andrey G., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Journal of pharmaceutical and biomedical analysis (30.11.2023)
Published in Journal of pharmaceutical and biomedical analysis (30.11.2023)
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Journal Article
(+)-Usnic Acid and Its Derivatives as Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses
Filimonov, Aleksandr S, Yarovaya, Olga I, Zaykovskaya, Anna V, Rudometova, Nadezda B, Shcherbakov, Dmitriy N, Chirkova, Varvara Yu, Baev, Dmitry S, Borisevich, Sophia S, Luzina, Olga A, Pyankov, Oleg V, Maksyutov, Rinat A, Salakhutdinov, Nariman F
Published in Viruses (29.09.2022)
Published in Viruses (29.09.2022)
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Journal Article
Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives
Khvostov, Mikhail V, Gladkova, Elizaveta D, Borisov, Sergey A, Fedotova, Marina S, Zhukova, Nataliya A, Marenina, Mariya K, Meshkova, Yuliya V, Luzina, Olga A, Tolstikova, Tatiana G, Salakhutdinov, Nariman F
Published in International journal of molecular sciences (16.11.2022)
Published in International journal of molecular sciences (16.11.2022)
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Journal Article
Usnic acid based thiazole-hydrazones as multi-targeting inhibitors of a wide spectrum of SARS-CoV-2 viruses
Yarovaya, Olga I, Filimonov, Aleksandr S, Baev, Dmitriy S, Borisevich, Sophia S, Chirkova, Varvara Yu, Zaykovskaya, Anna V, Mordvinova, Ekaterina D, Belenkaya, Svetlana V, Shcherbakov, Dmitriy N, Luzina, Olga A, Pyankov, Oleg V, Salakhutdinov, Nariman F
Published in New journal of chemistry (06.11.2023)
Published in New journal of chemistry (06.11.2023)
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Journal Article
Hepatoprotective Effect of a New FFAR1 Agonist-N-Alkylated Isobornylamine
Pon Kina, Darya, Kuranov, Sergey, Khvostov, Mikhail, Zhukova, Nataliya, Meshkova, Yulia, Marenina, Mariya, Luzina, Olga, Tolstikova, Tatyana, Salakhutdinov, Nariman
Published in Molecules (Basel, Switzerland) (01.01.2023)
Published in Molecules (Basel, Switzerland) (01.01.2023)
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Journal Article
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor
Dyrkheeva, Nadezhda S, Malakhova, Anastasia A, Zakharenko, Aleksandra L, Okorokova, Larisa S, Shtokalo, Dmitriy N, Pavlova, Sophia V, Medvedev, Sergey P, Zakian, Suren M, Nushtaeva, Anna A, Tupikin, Alexey E, Kabilov, Marsel R, Khodyreva, Svetlana N, Luzina, Olga A, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
The Study of Hypoglycemic Activity of 7-Terpenylcoumarins
Kuranov, Sergey, Marenina, Mariya, Ivankin, Dmitriy, Blokhin, Mikhail, Borisov, Sergey, Khomenko, Tatyana, Luzina, Olga, Khvostov, Mikhail, Volcho, Konstantin, Tolstikova, Tatyana, Salakhutdinov, Nariman
Published in Molecules (Basel, Switzerland) (07.12.2022)
Published in Molecules (Basel, Switzerland) (07.12.2022)
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Journal Article
Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40)
Kuranov, Sergey O., Luzina, Olga A., Onopchenko, Oleksandra, Pishel, Iryna, Zozulya, Sergey, Gureev, Maxim, Salakhutdinov, Nariman F., Krasavin, Mikhail
Published in Bioorganic chemistry (01.06.2020)
Published in Bioorganic chemistry (01.06.2020)
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