Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
Tombor, Lukas S., John, David, Glaser, Simone F., Luxán, Guillermo, Forte, Elvira, Furtado, Milena, Rosenthal, Nadia, Baumgarten, Nina, Schulz, Marcel H., Wittig, Janina, Rogg, Eva-Maria, Manavski, Yosif, Fischer, Ariane, Muhly-Reinholz, Marion, Klee, Kathrin, Looso, Mario, Selignow, Carmen, Acker, Till, Bibli, Sofia-Iris, Fleming, Ingrid, Patrick, Ralph, Harvey, Richard P., Abplanalp, Wesley T., Dimmeler, Stefanie
Published in Nature communications (29.01.2021)
Published in Nature communications (29.01.2021)
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Journal Article
Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis
MacGrogan, Donal, D’Amato, Gaetano, Travisano, Stanislao, Martinez-Poveda, Beatriz, Luxán, Guillermo, del Monte-Nieto, Gonzalo, Papoutsi, Tania, Sbroggio, Mauro, Bou, Vanesa, Gomez-del Arco, Pablo, Gómez, Manuel Jose, Zhou, Bin, Redondo, Juan Miguel, Jiménez-Borreguero, Luis J, de la Pompa, José Luis
Published in Circulation research (13.05.2016)
Published in Circulation research (13.05.2016)
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Journal Article
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants
Wagner, Julian U. G., Bojkova, Denisa, Shumliakivska, Mariana, Luxán, Guillermo, Nicin, Luka, Aslan, Galip S., Milting, Hendrik, Kandler, Joshua D., Dendorfer, Andreas, Heumueller, Andreas W., Fleming, Ingrid, Bibli, Sofia-Iris, Jakobi, Tobias, Dieterich, Christoph, Zeiher, Andreas M., Ciesek, Sandra, Cinatl, Jindrich, Dimmeler, Stefanie
Published in Basic research in cardiology (05.07.2021)
Published in Basic research in cardiology (05.07.2021)
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Journal Article
Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy
Luxán, Guillermo, Casanova, Jesús C, Martínez-Poveda, Beatriz, Prados, Belén, D'Amato, Gaetano, MacGrogan, Donal, Gonzalez-Rajal, Alvaro, Dobarro, David, Torroja, Carlos, Martinez, Fernando, Izquierdo-García, José Luis, Fernández-Friera, Leticia, Sabater-Molina, María, Kong, Young-Y, Pizarro, Gonzalo, Ibañez, Borja, Medrano, Constancio, García-Pavía, Pablo, Gimeno, Juan R, Monserrat, Lorenzo, Jiménez-Borreguero, Luis J, de la Pompa, José Luis
Published in Nature medicine (01.02.2013)
Published in Nature medicine (01.02.2013)
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Journal Article
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Bojkova, Denisa, Wagner, Julian U G, Shumliakivska, Mariana, Aslan, Galip S, Saleem, Umber, Hansen, Arne, Luxán, Guillermo, Günther, Stefan, Pham, Minh Duc, Krishnan, Jaya, Harter, Patrick N, Ermel, Utz H, Frangakis, Achilleas S, Milting, Hendrik, Zeiher, Andreas M, Klingel, Karin, Cinatl, Jindrich, Dendorfer, Andreas, Eschenhagen, Thomas, Tschöpe, Carsten, Ciesek, Sandra, Dimmeler, Stefanie
Published in Cardiovascular Research (01.12.2020)
Published in Cardiovascular Research (01.12.2020)
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Journal Article
Web Resource
Endothelial EphB4 maintains vascular integrity and transport function in adult heart
Luxán, Guillermo, Stewen, Jonas, Díaz, Noelia, Kato, Katsuhiro, Maney, Sathish K, Aravamudhan, Anusha, Berkenfeld, Frank, Nagelmann, Nina, Drexler, Hannes Ca, Zeuschner, Dagmar, Faber, Cornelius, Schillers, Hermann, Hermann, Sven, Wiseman, John, Vaquerizas, Juan M, Pitulescu, Mara E, Adams, Ralf H
Published in eLife (29.11.2019)
Published in eLife (29.11.2019)
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Journal Article
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts
Shumliakivska, Mariana, Luxán, Guillermo, Hemmerling, Inga, Scheller, Marina, Li, Xue, Müller-Tidow, Carsten, Schuhmacher, Bianca, Sun, Zhengwu, Dendorfer, Andreas, Debes, Alisa, Glaser, Simone-Franziska, Muhly-Reinholz, Marion, Kirschbaum, Klara, Hoffmann, Jedrzej, Nagel, Eike, Puntmann, Valentina O., Cremer, Sebastian, Leuschner, Florian, Abplanalp, Wesley Tyler, John, David, Zeiher, Andreas M., Dimmeler, Stefanie
Published in Nature communications (19.01.2024)
Published in Nature communications (19.01.2024)
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Journal Article
Morphogenesis of myocardial trabeculae in the mouse embryo
Captur, Gabriella, Wilson, Robert, Bennett, Michael F, Luxán, Guillermo, Nasis, Arthur, la Pompa, José Luis, Moon, James C, Mohun, Timothy J
Published in Journal of anatomy (01.08.2016)
Published in Journal of anatomy (01.08.2016)
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Journal Article
Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease
Cremer, Sebastian, Pilgram, Lisa, Berkowitsch, Alexander, Stecher, Melanie, Rieg, Siegbert, Shumliakivska, Mariana, Bojkova, Denisa, Wagner, Julian Uwe Gabriel, Aslan, Galip Servet, Spinner, Christoph, Luxán, Guillermo, Hanses, Frank, Dolff, Sebastian, Piepel, Christiane, Ruppert, Clemens, Guenther, Andreas, Rüthrich, Maria Madeleine, Vehreschild, Jörg Janne, Wille, Kai, Haselberger, Martina, Heuzeroth, Hanno, Hansen, Arne, Eschenhagen, Thomas, Cinatl, Jindrich, Ciesek, Sandra, Dimmeler, Stefanie, Borgmann, Stefan, Zeiher, Andreas
Published in PloS one (21.10.2021)
Published in PloS one (21.10.2021)
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Journal Article
Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease
Sebastian Cremer, Lisa Pilgram, Alexander Berkowitsch, Melanie Stecher, Siegbert Rieg, Mariana Shumliakivska, Denisa Bojkova, Julian Uwe Gabriel Wagner, Galip Servet Aslan, Christoph Spinner, Guillermo Luxán, Frank Hanses, Sebastian Dolff, Christiane Piepel, Clemens Ruppert, Andreas Guenther, Maria Madeleine Rüthrich, Jörg Janne Vehreschild, Kai Wille, Martina Haselberger, Hanno Heuzeroth, Arne Hansen, Thomas Eschenhagen, Jindrich Cinatl, Sandra Ciesek, Stefanie Dimmeler, Stefan Borgmann, Andreas Zeiher, on behalf of the LEOSS study group
Published in PloS one (21.10.2021)
Published in PloS one (21.10.2021)
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Journal Article
Endocardial Notch Signaling in Cardiac Development and Disease
Luxán, Guillermo, D’Amato, Gaetano, MacGrogan, Donal, de la Pompa, José Luis
Published in Circulation research (08.01.2016)
Published in Circulation research (08.01.2016)
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Journal Article
Fibroblast‐mediated intercellular crosstalk in the healthy and diseased heart
Nicin, Luka, Wagner, Julian U. G., Luxán, Guillermo, Dimmeler, Stefanie
Published in FEBS letters (01.03.2022)
Published in FEBS letters (01.03.2022)
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Journal Article
Post-myocardial infarction heart failure dysregulates the bone vascular niche
Hoffmann, Jedrzej, Luxán, Guillermo, Abplanalp, Wesley Tyler, Glaser, Simone-Franziska, Rasper, Tina, Fischer, Ariane, Muhly-Reinholz, Marion, Potente, Michael, Assmus, Birgit, John, David, Zeiher, Andreas Michael, Dimmeler, Stefanie
Published in Nature communications (25.06.2021)
Published in Nature communications (25.06.2021)
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Journal Article
Sequential Notch activation regulates ventricular chamber development
D’Amato, Gaetano, Luxán, Guillermo, del Monte-Nieto, Gonzalo, Martínez-Poveda, Beatriz, Torroja, Carlos, Walter, Wencke, Bochter, Matthew S., Benedito, Rui, Cole, Susan, Martinez, Fernando, Hadjantonakis, Anna-Katerina, Uemura, Akiyoshi, Jiménez-Borreguero, Luis J., de la Pompa, José Luis
Published in Nature cell biology (01.01.2016)
Published in Nature cell biology (01.01.2016)
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Journal Article
Notch activation stimulates migration of breast cancer cells and promotes tumor growth
Bolós, Victoria, Mira, Emilia, Martínez-Poveda, Beatriz, Luxán, Guillermo, Cañamero, Marta, Martínez-A, Carlos, Mañes, Santos, de la Pompa, José Luis
Published in Breast cancer research : BCR (04.07.2013)
Published in Breast cancer research : BCR (04.07.2013)
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Journal Article
Aging impairs the neurovascular interface in the heart
Wagner, Julian U G, Tombor, Lukas S, Malacarne, Pedro Felipe, Kettenhausen, Lisa-Maria, Panthel, Josefine, Kujundzic, Haris, Manickam, Nivethitha, Schmitz, Katja, Cipca, Maria, Stilz, Kathrin A, Fischer, Ariane, Muhly-Reinholz, Marion, Abplanalp, Wesley T, John, David, Mohanta, Sarajo K, Weber, Christian, Habenicht, Andreas J R, Buchmann, Giulia K, Angendohr, Stephan, Amin, Ehsan, Scherschel, Katharina, Klöcker, Nikolaj, Kelm, Malte, Schüttler, Dominik, Clauss, Sebastian, Günther, Stefan, Boettger, Thomas, Braun, Thomas, Bär, Christian, Pham, Minh-Duc, Krishnan, Jaya, Hille, Susanne, Müller, Oliver J, Bozoglu, Tarik, Kupatt, Christian, Nardini, Eleonora, Osmanagic-Myers, Selma, Meyer, Christian, Zeiher, Andreas M, Brandes, Ralf P, Luxán, Guillermo, Dimmeler, Stefanie
Published in Science (American Association for the Advancement of Science) (25.08.2023)
Published in Science (American Association for the Advancement of Science) (25.08.2023)
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Journal Article