Thromboxane synthase inhibitors. Synthesis and pharmacological activity of (R)-, (S)-, and (.+-.)-2,2-dimethyl-6-[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)methoxy]methyl]ethoxy]hexanoic acids
Manley, Paul W, Tuffin, David P, Allanson, Nigel M, Buckle, Philip E, Lad, Nagin, Lai, Steve M. F, Lunt, David O, Porter, Roderick A, Wade, Patricia J
Published in Journal of medicinal chemistry (01.10.1987)
Published in Journal of medicinal chemistry (01.10.1987)
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A structurally novel inhibitor of cGMP phosphodiesterase with vasodilator activity
Booth, R F, Lunt, D O, Lad, N, Buckham, S P, Oswald, S, Clough, D P, Floyd, C D, Dickens, J
Published in Biochemical pharmacology (15.11.1990)
Published in Biochemical pharmacology (15.11.1990)
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Structure-activity relationships in an imidazole-based series of thromboxane synthase inhibitors
Manley, Paul W., Allanson, Nigel M., Booth, Robert F. G., Buckle, Philip E., Kuzniar, Edward J., Lad, Nagin, Lai, Steve M. F., Lunt, David O., Tuffin, David P.
Published in Journal of medicinal chemistry (01.09.1987)
Published in Journal of medicinal chemistry (01.09.1987)
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Dibenzoquinazoline diones as antihypertensive cyclic guanosine monophosphate phosphodiesterase inhibitors
Booth, R F, Buckham, S P, Lunt, D O, Manley, P W, Porter, R A
Published in Biochemical pharmacology (15.10.1987)
Published in Biochemical pharmacology (15.10.1987)
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