Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro
Taki, Aya C., Jabbar, Abdul, Kurz, Thomas, Lungerich, Beate, Ma, Guangxu, Byrne, Joseph J., Pflieger, Marc, Asfaha, Yodita, Fischer, Fabian, Chang, Bill C. H., Sleebs, Brad E., Gasser, Robin B.
Published in Molecules (Basel, Switzerland) (10.05.2021)
Published in Molecules (Basel, Switzerland) (10.05.2021)
Get full text
Journal Article
Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation
Berger, Alexander, Knak, Talea, Kiffe-Delf, Anna-Lene, Mudrovcic, Korana, Singh, Vinayak, Njoroge, Mathew, Burckhardt, Bjoern B., Gopalswamy, Mohanraj, Lungerich, Beate, Ackermann, Lutz, Gohlke, Holger, Chibale, Kelly, Kalscheuer, Rainer, Kurz, Thomas
Published in Pharmaceuticals (Basel, Switzerland) (10.08.2022)
Published in Pharmaceuticals (Basel, Switzerland) (10.08.2022)
Get full text
Journal Article
Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation
Zajíčková, Markéta, Prchal, Lukáš, Vokřál, Ivan, Nguyen, Linh Thuy, Kurz, Thomas, Gasser, Robin, Bednářová, Klára, Mičundová, Magdalena, Lungerich, Beate, Michel, Oliver, Skálová, Lenka
Published in Pharmaceutics (30.03.2022)
Published in Pharmaceutics (30.03.2022)
Get full text
Journal Article
Phenotypic screening of the 'Kurz-box' of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus
Nguyen, Linh Thuy, Kurz, Thomas, Preston, Sarah, Brueckmann, Hjoerdis, Lungerich, Beate, Herath, H M P Dilrukshi, Koehler, Anson V, Wang, Tao, Skálová, Lenka, Jabbar, Abdul, Gasser, Robin B
Published in Parasites & vectors (30.04.2019)
Published in Parasites & vectors (30.04.2019)
Get full text
Journal Article
Inhibition of the Yersinia pestis Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis by α‑Phenyl-Substituted Reverse Fosmidomycin Analogues
Ball, Haley S, Girma, Misgina, Zainab, Mosufa, Riley, Honoria, Behrendt, Christoph T, Lienau, Claudia, Konzuch, Sarah, Avelar, Leandro A. A, Lungerich, Beate, Soojhawon, Iswarduth, Noble, Schroeder M, Kurz, Thomas, Couch, Robin D
Published in ACS omega (17.03.2020)
Published in ACS omega (17.03.2020)
Get full text
Journal Article
3‑Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum
Knaab, Tanja C, Held, Jana, Burckhardt, Bjoern B, Rubiano, Kelly, Okombo, John, Yeo, Tomas, Mok, Sachel, Uhlemann, Anne-Catrin, Lungerich, Beate, Fischli, Christoph, Pessanha de Carvalho, Lais, Mordmüller, Benjamin, Wittlin, Sergio, Fidock, David A, Kurz, Thomas
Published in Journal of medicinal chemistry (25.03.2021)
Published in Journal of medicinal chemistry (25.03.2021)
Get full text
Journal Article
Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity
Lienau, Claudia, Gräwert, Tobias, Alves Avelar, Leandro A., Illarionov, Boris, Held, Jana, Knaab, Tanja C., Lungerich, Beate, van Geelen, Lasse, Meier, Dieter, Geissler, Stefanie, Cynis, Holger, Riederer, Ulrich, Buchholz, Mirko, Kalscheuer, Rainer, Bacher, Adelbert, Mordmüller, Benjamin, Fischer, Markus, Kurz, Thomas
Published in European journal of medicinal chemistry (01.11.2019)
Published in European journal of medicinal chemistry (01.11.2019)
Get full text
Journal Article
Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium-H-Hydroxylation
Berger, Alexander, Knak, Talea, Kiffe-Delf, Anna-Lene, Mudrovcic, Korana, Singh, Vinayak, Njoroge, Mathew, Burckhardt, Bjoern B, Gopalswamy, Mohanraj, Lungerich, Beate, Ackermann, Lutz, Gohlke, Holger, Chibale, Kelly, Kalscheuer, Rainer, Kurz, Thomas
Published in Pharmaceuticals (Basel, Switzerland) (01.08.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.08.2022)
Get full text
Journal Article
Synthesis of thiazolyl-based hydroxamic acids as histone deacetylase inhibitors
Asfaha, Yodita, Skerhut, Alexander Jan, Alves-Avelar, Leandro A., Horstick-Muche, Nadine, Lungerich, Beate, Klinken, Stefan, Kassack, Matthias U., Kurz, Thomas
Published in ARKIVOC free online journal of organic chemistry (01.01.2020)
Published in ARKIVOC free online journal of organic chemistry (01.01.2020)
Get full text
Journal Article
Development of a First-in-Class Small-Molecule Inhibitor of the C‑Terminal Hsp90 Dimerization
Bhatia, Sanil, Spanier, Lukas, Bickel, David, Dienstbier, Niklas, Woloschin, Vitalij, Vogt, Melina, Pols, Henrik, Lungerich, Beate, Reiners, Jens, Aghaallaei, Narges, Diedrich, Daniela, Frieg, Benedikt, Schliehe-Diecks, Julian, Bopp, Bertan, Lang, Franziska, Gopalswamy, Mohanraj, Loschwitz, Jennifer, Bajohgli, Baubak, Skokowa, Julia, Borkhardt, Arndt, Hauer, Julia, Hansen, Finn K., Smits, Sander H. J., Jose, Joachim, Gohlke, Holger, Kurz, Thomas
Published in ACS central science (25.05.2022)
Published in ACS central science (25.05.2022)
Get full text
Journal Article
3-Hydroxy-N '-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally
Leven, Michael, Knaab, Tanja C., Held, Jana, Duffy, Sandra, Meister, Stephan, Fischli, Christoph, Meitzner, Diane, Lehmann, Ursula, Lungerich, Beate, Kuna, Krystina, Stahlke, Petra, Delves, Michael, Buchholz, Mirko, Winzeler, Elizabeth A., Avery, Vicky M., Mordmueller, Benjamin, Wittlin, Sergio, Kurz, Thomas
Published in Journal of medicinal chemistry (27.07.2017)
Published in Journal of medicinal chemistry (27.07.2017)
Get full text
Journal Article
Isophthalic Acid‐Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni
Stenzel, Katharina, Chakrabarti, Alokta, Melesina, Jelena, Hansen, Finn K., Lancelot, Julien, Herkenhöhner, Simon, Lungerich, Beate, Marek, Martin, Romier, Christophe, Pierce, Raymond. J., Sippl, Wolfgang, Jung, Manfred, Kurz, Thomas
Published in Archiv der Pharmazie (Weinheim) (01.08.2017)
Published in Archiv der Pharmazie (Weinheim) (01.08.2017)
Get full text
Journal Article
3‑Hydroxy‑N′‑arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally
Leven, Michael, Knaab, Tanja C, Held, Jana, Duffy, Sandra, Meister, Stephan, Fischli, Christoph, Meitzner, Diane, Lehmann, Ursula, Lungerich, Beate, Kuna, Krystina, Stahlke, Petra, Delves, Michael J, Buchholz, Mirko, Winzeler, Elizabeth A, Avery, Vicky M, Mordmüller, Benjamin, Wittlin, Sergio, Kurz, Thomas
Published in Journal of medicinal chemistry (27.07.2017)
Published in Journal of medicinal chemistry (27.07.2017)
Get full text
Journal Article